Comparison of methods for in-house screening of HLA*B57:01 to prevent abacavir hypersensitivity in HIV-1 care [PDF]
, 2015 Abacavir is a nucleoside reverse transcriptase inhibitor used as part of combination antiretroviral therapy in HIV-1-infected patients. Because this drug can cause a hypersensitivity reaction that is correlated with the presence of the HLA-B*57:01 ...
Bonczkowski, Pawel +18 more
core +11 more sources
Revised scored sensory perception quotient reveals sensory hypersensitivity in women with autism [PDF]
, 2020 Previous research using the Sensory Perception Quotient (SPQ) has reported greater sensory hypersensitivity in people with autism spectrum condition (ASC) compared to controls, consistent with other research.
Ashwin, Chris +4 more
core +6 more sources
Progress in understanding hypersensitivity reactions to nonsteroidal anti‐inflammatory drugs
Allergy. European Journal of Allergy and Clinical Immunology, 2020 Nonsteroidal anti‐inflammatory drugs (NSAIDs), the medications most commonly used for treating pain and inflammation, are the main triggers of drug hypersensitivity reactions.
I. Doña +6 more
semanticscholar +1 more source
Quaternary ammonium compounds in hypersensitivity reactions
Frontiers in Toxicology, 2022 Quaternary ammonium compounds (QAC) are commonly used disinfectants, antiseptics, preservatives, and detergents due to their antibacterial property and represent the first used biocides before phenolic or nitrogen products.
Marine Peyneau +7 more
doaj +1 more source
Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication [PDF]
, 2013 Replication Protein A (RPA) is a heterotrimeric protein complex that binds single-stranded DNA. In plants, multiple genes encode the three RPA subunits (RPA1, RPA2 and RPA3), including five RPA1-like genes in Arabidopsis.
Aklilu, Behailu B. +2 more
core +5 more sources
Towards a more precise diagnosis of hypersensitivity to beta‐lactams — an EAACI position paper
Allergy. European Journal of Allergy and Clinical Immunology, 2019 A recent survey of the European Academy of Allergy and Clinical Immunology (EAACI) Drug Allergy Interest Group (DAIG) on how European allergy specialists deal with beta‐lactam (BL) hypersensitivity demonstrated a significant heterogeneity in current ...
A. Romano +14 more
semanticscholar +1 more source
siRNA knockdown of SPHK1 in vivo protects mice from systemic, type-I Allergy. [PDF]
, 2007 Systemic anaphylaxis is considered to be a typical immediate hypersensitivity response, determined by the activation of immune cells, via antigen-induced aggregation of IgE-sensitized FcεRI cells.
Alirio Jose A. J. Melendez +2 more
core +2 more sources
Update on pathobiology in Stevens-Johnson syndrome and toxic epidermal necrolysis
Dermatologica Sinica, 2013 Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) are rare but life-threatening severe cutaneous adverse reactions (SCARs), which are mainly induced by a variety of drugs. Once considered to be unpredictable, significant progress has been
Shih-Chi Su, Wen-Hung Chung
doaj +1 more source
Cytotoxic Proteins and Therapeutic Targets in Severe Cutaneous Adverse Reactions
Toxins, 2014 Severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN), are rare but life-threatening conditions induced mainly by a variety of drugs.
Shih-Chi Su, Wen-Hung Chung
doaj +1 more source
Acute generalized exanthematous pustulosis: A retrospective study of 51 cases in Taiwan
Dermatologica Sinica, 2014 Background/Objective: Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse drug reaction characterized by fever and numerous sterile non-follicular pustules.
Yung-Yi Lee, Wen-Hung Chung
doaj +1 more source