Results 21 to 30 of about 200,525 (304)

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania, Barni, Simona, Bottau, Paolo, Caffarelli, Carlo, Caimmi, Davide, Caimmi, Silvia, Cardinale, Fabio, Comberiati, Pasquale, Crisafulli, SEBASTIANO GIUSEPPE, Di Mauro, Dora, Diaferio, Lucia, Duse, Marzia, Franceschini, Fabrizio, Liotti, Lucia, Marseglia, Gianluigi, Mastrorilli, Carla, Mori, Francesca, Paravati, Francesco, Pelosi, Umberto, Saretta, Francesca   +19 more
core   +1 more source

An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity

Journal of Immunology Research, 2018
Drug hypersensitivity may manifest ranging from milder skin reactions (e.g., maculopapular exanthema and urticaria) to severe systemic reactions, such as anaphylaxis, drug reactions with eosinophilia and systemic symptoms (DRESS)/drug-induced ...
Chun-Bing Chen, Riichiro Abe, Ren-You Pan, Chuang-Wei Wang, Shuen-Iu Hung, Yi-Giien Tsai, Wen-Hung Chung   +6 more
doaj   +1 more source

siRNA knockdown of SPHK1 in vivo protects mice from systemic, type-I Allergy. [PDF]

, 2007
Systemic anaphylaxis is considered to be a typical immediate hypersensitivity response, determined by the activation of immune cells, via antigen-induced aggregation of IgE-sensitized FcεRI cells.
Alirio Jose A. J. Melendez, Jayapal J. Manikandan, Peter Natesan P. N. Pushparaj   +2 more
core   +2 more sources

In the hour of Sugammadex [PDF]

Korean Journal of Anesthesiology, 2013
Sugammadex is a modified gamma-cyclodextrin which is showing favorable outcomes regarding reversal of neuromuscular blockade, especially by rocuronium.
Jin Young Chon
doaj   +1 more source

A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensivity in a patient with xeroderma pigmentosum [PDF]

, 2010
Background: Radiotherapy-induced DNA double-strand breaks (DSBs) are critical cytotoxic lesions. Inherited defects in DNA DSB repair pathways lead to hypersensitivity to ionising radiation, immunodeficiency and increased cancer incidence.
Abbaszadeh, Fatemah, Arlett, Colin F., Bourton, E.C, Clingen, Peter H., Green, M H, Makarov, E.M., Newbold, R.F, Parris, C.N., Plowman, P.N, Themis, M.   +9 more
core   +1 more source

HLA Association with Drug-Induced Adverse Reactions

Journal of Immunology Research, 2017
Adverse drug reactions (ADRs) remain a common and major problem in healthcare. Severe cutaneous adverse drug reactions (SCARs), such as Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) with mortality rate ranges from 10% to more than 30 ...
Wen-Lang Fan, Meng-Shin Shiao, Rosaline Chung-Yee Hui, Shih-Chi Su, Chuang-Wei Wang, Ya-Ching Chang, Wen-Hung Chung   +6 more
doaj   +1 more source

Hypersensitivity and chaos signatures in the quantum baker's maps [PDF]

, 2006
Classical chaotic systems are distinguished by their sensitive dependence on initial conditions. The absence of this property in quantum systems has lead to a number of proposals for perturbation-based characterizations of quantum chaos, including linear
A J Scott, Abreu R F Vallejos R O, Anantharaman N Nonnenmacher S, Carlton M Caves, Caves C M, Eiben A E, Ermann L Saraceno M, Gorin T Prosen T Seligman T H Znidaric M, Haake F, Kraus K, Lichtenberg A J, Nielsen M A, Peres A, Peres A, Rüdiger Schack, Scott A J, Todd A Brun, Tracy M M   +17 more
core   +2 more sources

A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy [PDF]

, 2016
The research leading to these results is part of the EUROPAIN Collaboration, which has received support from the Innovative Medicines Initiative Joint Undertaking, under grant agreement no 115007, resources of which are composed of financial contribution
Banerjee, Beggs, Bhangoo, Blackbeard, Bridges, Calvo, Cheng, Cherry, Cherry, Distler, Ellis, Ellis, Evans, Gore, Hasnie, Herzberg, Huang, Joseph, Joseph, Joseph, Kamerman, Keswani, Keswani, Kilkenny, Lauria, Lauria, Lauria, Lichtenstein, Macleod, Maritz, Martin, McArthur, Meyer-Rosberg, Nicholson, Novak, Oh, Pettersen, Phillips, Phillips, Polydefkis, Rice, Simpson, Smyth, Verma, Wadley, Wallace, Wallace, Wallace, Wallace, Zheng, Zimmermann   +50 more
core   +1 more source

Hydrolyzed Protein Formula for Allergy Prevention in Preterm Infants: Follow-Up Analysis of a Randomized, Triple-Blind, Placebo-Controlled Study

Frontiers in Pediatrics, 2020
Background: Allergic diseases are a major public health burden worldwide. Evidence suggests that early nutrition might play a key role in the future development of allergies and the use of hydrolyzed protein formulas have been proposed to prevent ...
Antonio Di Mauro, Maria Elisabetta Baldassarre, Giulia Brindisi, Anna Maria Zicari, Martina Tarantini, Nicla Laera, Manuela Capozza, Raffaella Panza, Silvia Salvatore, Licia Pensabene, Margherita Fanelli, Nicola Laforgia   +11 more
doaj   +1 more source

Drug Allergy Profile From a National Drug Allergy Registry

Frontiers in Pharmacology, 2021
Background: Drug hypersensitivity reactions (DHRs) are among the most frequent reasons for consultation in allergy departments and are becoming more common due to increasing prevalence and case complexity.Objective: To describe the most common drugs ...
Mona Al-Ahmad, Mona Al-Ahmad, Jusufovic Edin, Fardous Musa, Tito Rodriguez-Bouza   +4 more
doaj   +1 more source