Results 31 to 40 of about 275,364 (194)

Immune checkpoint inhibitor-induced severe epidermal necrolysis mediated by macrophage-derived CXCL10 and abated by TNF blockade

open access: yesNature Communications
Immune checkpoint inhibitors (ICI) represent new anticancer agents and have been used worldwide. However, ICI can potentially induce life-threatening severe cutaneous adverse reaction (SCAR), such as Stevens-Johnson syndrome/toxic epidermal necrolysis ...
Chun-Bing Chen   +31 more
doaj   +1 more source

Clinical Characteristics and Disease Burden of Patients with Moderate-to-Severe Generalized Pustular Psoriasis Flares in Taiwan

open access: yesDermatology and Therapy
Introduction Generalized pustular psoriasis (GPP) is a rare and severe psoriasis subtype characterized by the rapid onset of coalescing sterile pustules over broad body areas and systemic inflammation.
Chun-Wei Lu   +10 more
doaj   +1 more source

Allergic asthma and rhinitis comorbidity [PDF]

open access: yesVojnosanitetski Pregled, 2015
nema
Zvezdin Biljana   +6 more
doaj   +1 more source

Hydrolyzed Protein Formula for Allergy Prevention in Preterm Infants: Follow-Up Analysis of a Randomized, Triple-Blind, Placebo-Controlled Study

open access: yesFrontiers in Pediatrics, 2020
Background: Allergic diseases are a major public health burden worldwide. Evidence suggests that early nutrition might play a key role in the future development of allergies and the use of hydrolyzed protein formulas have been proposed to prevent ...
Antonio Di Mauro   +11 more
doaj   +1 more source

Mechanisms of Hypersensitivity [PDF]

open access: yes, 2013
Allergic reactions to drugs are not always the result of the drug’s protein-binding capacity, biotransformation, or degradation. Mediator release may occur via cross-linking of cell-bound IgE by di-(multi-) valent free drug. Physiological and pharmacological effects of histamine are mediated through four receptors, H(1), H(2), H(3), and H(4.) The H(3 ...
Brian A. Baldo, Nghia H. Pham
openaire   +2 more sources

Efficacy and safety of indigo naturalis oil extract (Lindioil ointment) for the treatment of atopic dermatitis: a randomized, crossover, evaluator-blinded, controlled trial

open access: yesFrontiers in Pharmacology
IntroductionLindioil ointment or its compound formulations are commonly used traditional Chinese medicine practitioners to treat adult eczema or localized dermatitis.
Chin-Yi Yang   +24 more
doaj   +1 more source

Hypersensitivity Angiitis

open access: yesJournal of Investigative Dermatology, 1989
Hypersensitivity angiitis is a disease in which patients present with palpable purpura dominant on the lower legs. As lesions evolve they become confluent, and sometimes hemorrhagic and ulcerate. Other organ systems may be involved, particularly the joints, gastrointestinal tract, and kidneys. Current evidence supports an immune complex pathogenesis in
openaire   +2 more sources

Perfuração dos lóbulos das orelhas como fator de risco para o desenvolvimento de alergia de contato ao níquel Ear piercing as a risk factor for contact allergy to nickel

open access: yesJornal de Pediatria, 2010
OBJETIVOS: Determinar a prevalência da alergia de contato aos metais em crianças que frequentam um centro de saúde e caracterizar o subgrupo com alergia em relação aos fatores de risco.
Marilda H. T. Brandão   +3 more
doaj   +1 more source

SoundFields: A Virtual Reality Home-Based Intervention for Auditory Hypersensitivity Experienced by Autistic Children

open access: yesApplied Sciences, 2023
Previous studies have shown that autistic people often display atypical responses when processing sensory information, with particular prevalence within the auditory domain.
Sarah Parkinson   +6 more
doaj   +1 more source

Regulatory T Cell-Targeted Immunomodulatory Therapy for Long-Term Clinical Improvement of Atopic Dermatitis: Hypotheses and Perspectives

open access: yesLife, 2023
Atopic dermatitis (AD) is a chronically relapsing inflammatory skin disorder characterized by itching and eczematous lesions. It is often associated with a personal or familial history of allergic diseases. Allergic inflammation induced by immunoglobulin
Dong-Ho Nahm
doaj   +1 more source

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