Results 31 to 40 of about 521,930 (421)

siRNA knockdown of SPHK1 in vivo protects mice from systemic, type-I Allergy. [PDF]

open access: yes, 2007
Systemic anaphylaxis is considered to be a typical immediate hypersensitivity response, determined by the activation of immune cells, via antigen-induced aggregation of IgE-sensitized FcεRI cells.
Alirio Jose A. J. Melendez   +2 more
core   +2 more sources

HLA-B*5701 screening for hypersensitivity to abacavir.

open access: yesNew England Journal of Medicine, 2008
BACKGROUND Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to ...
S. Mallal   +17 more
semanticscholar   +1 more source

The effects of coloring therapy on patients with generalized anxiety disorder

open access: yesAnimal Models and Experimental Medicine, Volume 5, Issue 6, Page 502-512, December 2022., 2022
After the intervention, there were statistical differences intra‐and‐inter group comparisons of anxiety, depression, and positive and negative mood scales in the experimental and control groups (p < .05). The minus in anxiety/positive emotions pre‐and‐post intervention in the experimental group was statistically significant compared to the minus in ...
Bosomtwe Samuel   +6 more
wiley   +1 more source

In the hour of Sugammadex [PDF]

open access: yesKorean Journal of Anesthesiology, 2013
Sugammadex is a modified gamma-cyclodextrin which is showing favorable outcomes regarding reversal of neuromuscular blockade, especially by rocuronium.
Jin Young Chon
doaj   +1 more source

A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensivity in a patient with xeroderma pigmentosum [PDF]

open access: yes, 2010
Background: Radiotherapy-induced DNA double-strand breaks (DSBs) are critical cytotoxic lesions. Inherited defects in DNA DSB repair pathways lead to hypersensitivity to ionising radiation, immunodeficiency and increased cancer incidence.
Abbaszadeh, Fatemah   +9 more
core   +1 more source

HLA Association with Drug-Induced Adverse Reactions

open access: yesJournal of Immunology Research, 2017
Adverse drug reactions (ADRs) remain a common and major problem in healthcare. Severe cutaneous adverse drug reactions (SCARs), such as Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) with mortality rate ranges from 10% to more than 30 ...
Wen-Lang Fan   +6 more
doaj   +1 more source

Exposing Hypersensitivity in Quantum Chaotic Dynamics [PDF]

open access: yesarXiv, 2023
We demonstrate that the unitary dynamics of a multi-qubit system can display hypersensitivity to initial state perturbation. This contradicts the common belief that the classical approach based on the exponential divergence of initially neighboring trajectories cannot be applied to identify chaos in quantum systems.
arxiv  

A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy [PDF]

open access: yes, 2016
The research leading to these results is part of the EUROPAIN Collaboration, which has received support from the Innovative Medicines Initiative Joint Undertaking, under grant agreement no 115007, resources of which are composed of financial contribution
Banerjee   +50 more
core   +1 more source

Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice

open access: yesNature Communications, 2019
Spinal pain is a major clinical problem, however, its origins and underlying mechanisms remain unclear. Here we report that in mice, osteoclasts induce sensory innervation in the porous endplates which contributes to spinal hypersensitivity in mice ...
Shuangfei Ni   +24 more
semanticscholar   +1 more source

Hydrolyzed Protein Formula for Allergy Prevention in Preterm Infants: Follow-Up Analysis of a Randomized, Triple-Blind, Placebo-Controlled Study

open access: yesFrontiers in Pediatrics, 2020
Background: Allergic diseases are a major public health burden worldwide. Evidence suggests that early nutrition might play a key role in the future development of allergies and the use of hydrolyzed protein formulas have been proposed to prevent ...
Antonio Di Mauro   +11 more
doaj   +1 more source

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