Results 81 to 90 of about 509,314 (341)

The Distribution of Complement Proteins in Soft and Hard Coronas Impacts Macrophage Uptake of Nanoparticles

Advanced Healthcare Materials, EarlyView.
Protein corona plays a critical role in the biological behavior of nanoparticles. This study investigates the distribution of complement proteins in soft corona and their impact on the macrophage uptake of polymer nanoparticles. It underlines the significance of soft corona investigation for understanding in vivo performance of nanomedicines.
Ying Qiu, Tianchang He, Chunjie Miao, Xinyang Shi, Yuanyuan Niu, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +8 more
wiley   +1 more source

Chlorhexidine Allergy: Current Challenges and Future Prospects

Journal of Asthma and Allergy, 2020
Chirawat Chiewchalermsri,1,2 Mongkhon Sompornrattanaphan,3 Chamard Wongsa,3 Torpong Thongngarm3 1Division of Allergy and Clinical Immunology, Department of Medicine, Phramongkutklao Hospital, Bangkok, Thailand; 2Department of Medicine, Panyananthaphikkhu
Chiewchalermsri C, Sompornrattanaphan M, Wongsa C, Thongngarm T   +3 more
doaj  

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Carboplatin hypersensitivity in relapsed ovarian carcinoma: A therapeutic challenge

Indian Journal of Medical and Paediatric Oncology, 2014
Carboplatin and paclitaxel as doublet are the standard therapeutic option for advanced stage ovarian carcinoma in the first line as well as relapse. Carboplatin with its better toxicity profile has replaced cisplatin as the first line drug.
Avinash Pandey, Bharat Bhosale, Vimal Pandita, Ashish Singh, Joydeep Ghosh, Jaya Ghosh, Jyoti Bajpai   +6 more
doaj   +1 more source

A new mathematical model for radiation cell killing mechanism: Target cumulating model [PDF]

, 2009
There are numerous mathematical or statistical models have been given out for radiation cell killing mechanism. Unfortunately, none of the model could explain the mechanism perfectly.
Wu Shixiu, Xie Congyin, Zhang Li, Zhao Liang   +3 more
core   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

The Three R\u27s of Delayed Hypersensitivity [PDF]

, 1974
Delayed hypersensitivity is one of several immune responses initiated by thymus-derived (T) lymphocytes. The mononuclear infiltrate of delayed hypersensitivity is a collaborative phenomenon between T lymphocytes and monocytes.
Horwitz, David
core   +1 more source

Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans [PDF]

, 2014
Parkinson's disease (PD), the second most prevalent neurodegenerative disease after Alzheimer's disease, is linked to the gradual loss of dopaminergic neurons in the substantia nigra.
A Garcia-Espana, A Moszczynska, A Priyadarshi, Alexander Holmes, Anton Gartner, AT Allen, B Giros, C Boucheix, C Boucheix, C Boucheix, C Klein, C Missale, CD Dunn, CH Lai, D Vallone, DB Calne, DL Chase, E Rubinstein, E Rubinstein, EA Bolan, ER Sawin, ES Calipari, FJ Lee, FJ Lee, GC Cotzias, GR Uhl, H Maharaj, H Moribe, H Moribe, HP Rang, J Bove, J Sulston, JE Galvin, JG White, JM Beaulieu, JW Langston, K Jellinger, K Strange, K Tieu, KF Tipton, Kim A. Caldwell, L Carvelli, LD Jayanthi, M Santiago, MJ Ferris, MJ LaVoie, MJ Zigmond, ML Toth, MS Szczypka, MW Davis, MY Chang, N Chen, Neda Masoudi, O Thompson, P Seeman, P Seeman, P Sokoloff, Pablo Ibanez-Cruceyra, PW McDonald, QY Zhou, R Andrew, R Nass, R Nass, RM Kostrzewa, RR Gainetdinov, S Brenner, S Cao, S Charrin, S Fahn, S Fahn, S Thaminy, Sarah-Lena Offenburger, TN Chase, W Birkmayer, WA Cass, Y Glinka   +75 more
core   +5 more sources

Restoration of Cingulate Long-Term Depression by Enhancing Non-apoptotic Caspase 3 Alleviates Peripheral Pain Hypersensitivity [PDF]

, 2020
Yongjie Wang, Ming‐Gang Liu, Jinghua Wang, Wei Cao, Cheng Wu, Ziyue Wang, Li Liu, Fan Yang, Zhihui Feng, Li Sun, Fu-Xing Zhang, Yi Shen, Yudong Zhou, Min Zhuo, Jianhong Luo, Tian‐Le Xu, Xiang‐Yao Li   +16 more
openalex   +1 more source

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

Advanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim, Seokheon Hong, Jae Hwi Lee, Jongmin Lee, Jae Jun Kang, Jiseon Bae, Jino Kim, Dong‐Hwee Kim, Jin Yoo, Mi Sun Cha, Su Hee Kim, Youngmee Jung   +11 more
wiley   +1 more source