Results 81 to 90 of about 7,855 (207)

Anti-Ma-2 associated encephalitis presenting as slowly progressive dementia and cerebellar atrophy

open access: yesAnnals of Movement Disorders
Cognitive impairment can be a manifestation of a neurodegenerative disease or may have a reversible etiology. Among reversible causes, metabolic, nutritional and autoimmune conditions are commonly evaluated.
Somdattaa Ray   +2 more
doaj   +1 more source

Sleep-Wake Disorders and a Look at Insomnia through Biological and Behavioral Perspectives [PDF]

open access: yes, 2017
Insomnia is defined by difficulties in falling asleep, maintaining sleep, and problems with early morning awakenings. Unfortunately, due to these symptoms daytime fatigue often follows.
Fontanarosa, Mia
core   +1 more source

Choroid plexus alterations in long COVID and their associations with Alzheimer's disease risks

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Choroid plexus (ChP) enlargement is a neuroimaging biomarker of neuroinflammation and neurodegeneration. However, evidence of ChP structural and perfusion alterations in long coronavirus disease (COVID) and their clinical relevance remains limited.
Huize Pang   +11 more
wiley   +1 more source

Pharmacologic Treatments of Cocaine Dependence [PDF]

open access: yes, 2011
The rapid escalation of cocaine abuse in the United States in the 1980\u27s has generated a host of interesting hypotheses on various aspects of this problem.
Knable, D.O., Michael B.
core   +1 more source

Regulation of autophagy‐mediated pathways by diet, physical activity, and sleep in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Alzheimer's disease (AD) is a progressive, age‐related, neurodegenerative disorder marked by cognitive decline, memory loss, and accumulation of amyloid beta (Aβ) plaques and tau tangles. A key feature of AD is impaired protein homeostasis, often driven by autophagy dysfunction.
Ajish Ariyath   +9 more
wiley   +1 more source

Sleep, ageing and night work [PDF]

open access: yes, 2009
Studies have shown that the frequency or worsening of sleep disorders tends to increase with age and that the ability to perform circadian adjustments tends to decrease in individuals who work the night shift.
Bittencourt, Lia Rita Azeredo   +7 more
core   +1 more source

Epidemiology and Economic Burden of Sleep Disorders in Europe

open access: yesEuropean Journal of Neurology, Volume 33, Issue 2, February 2026.
We investigated the epidemiology and costs of five major sleep disorders in Europe using systematic literature reviews, data harmonization, and imputation. Estimated adult prevalence was 18% for OSA, 10% for insomnia, 3% for RLS, 0.03% for narcolepsy, and 0.009% for RBD. In 2019, OSA had the highest economic impact in high‐income Europe (€184 billion),
Claudio L. A. Bassetti   +14 more
wiley   +1 more source

Intensive Sleep Retraining and Total Sleep Deprivation for Treating Chronic Insomnia: A Randomised Controlled Trial

open access: yesJournal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT The aim of the study was to compare the efficacy of intensive sleep retraining (ISR) and total sleep deprivation (TSD) against a no‐treatment control condition for treating chronic insomnia and examine two potential mechanisms: the resolution of conditioned insomnia and the increase in homeostatic sleep drive produced by sleep deprivation ...
J. Le Bouthillier, H. Ivers, C. M. Morin
wiley   +1 more source

Exploring Outcome Measures for Mitochondrial Myopathies; Insights From a Longitudinal Study on TK2 Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Thymidine kinase 2 deficiency (TK2d) is an ultra‐rare autosomal recessive mitochondrial myopathy with variable presentations, including late‐onset forms beginning after age 12. Unlike early‐onset disease, the natural history of late‐onset TK2d remains poorly defined.
Paloma Martín‐Jimenez   +16 more
wiley   +1 more source

Diagnostics methods for sleep disorders [PDF]

open access: yes, 2005
The aim of this manuscript is to describe the procedures, recommendations, findings and value of the diagnostic methods used in Sleep Disorders including questionnaires, Actigraph, Polysomnography and Multiple sleep latency test.
Smith, Anna Karla, Togeiro, Sonia Maria
core   +4 more sources

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