Results 91 to 100 of about 8,412,631 (306)

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout, Joseph Sullivan, Stéphane Auvin, J. Helen Cross, Orrin Devinsky, Antonio Gil‐Nagel, Renzo Guerrini, Kelly G. Knupp, M. Scott Perry, Rocío Sánchez‐Carpintero, An‐Sofie Schoonjans, Ingrid E. Scheffer, Nicola Specchio, Adam Strzelczyk, James Wheless, Elaine C. Wirrell, Diego Morita, Patrick Healy, Mélanie Langlois, Amélie Lothe, Lieven Lagae   +20 more
wiley   +1 more source

Resolution of Severe Portopulmonary Hypertension With Inhaled Treprostinil and Liver Transplantation [PDF]

Texas Heart Institute Journal
Portopulmonary hypertension is a rare condition with a poor prognosis. Prompt management is essential for liver transplantation eligibility, a potentially curative option.
Alex J. Chang, MD, Choon Hwa Goh, MD
doaj   +1 more source

Pathophysiology of Portal Hypertension [PDF]

Clinics in Liver Disease, 1964
Portal hypertension is a major complication of liver disease that results from a variety of pathologic conditions that increase the resistance to the portal blood flow into the liver. As portal hypertension develops, the formation of collateral vessels and arterial vasodilation progresses, which results in increased blood flow to the portal circulation.
openaire   +2 more sources

Noncirrhotic Portal Hypertension [PDF]

Journal of Clinical and Experimental Hepatology, 2011
Portal hypertension is characterized by an increase in portal pressure (> 10 mmHg) and could be a result of cirrhosis of the liver or of noncirrhotic diseases. When portal hypertension occurs in the absence of liver cirrhosis, noncirrhotic portal hypertension (NCPH) must be considered. The prognosis of this disease is much better than that of cirrhosis.
Harshal, Rajekar, Rakesh K, Vasishta, Yogesh K, Chawla, Radha K, Dhiman   +3 more
openaire   +2 more sources

Engineered molecular diagnostic strategies for hepatocellular carcinoma: Integrating flexible photonic barcodes, liquid biopsies, and AI‐enhanced sensing platforms

FlexMat, EarlyView.
Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue, Wanqi Yang, Xiaoyu Liu, Xuehui Chu, Wei Li, Jinglin Wang   +5 more
wiley   +1 more source

Portal Hypertension in Children

, 2016
Portal hypertension is defined as an increase of blood pressure in the portal venous bed beyond the physiological values. In childhood it is usually caused by an increase of resistance to the blood flow from the mesenteric venous circulation through ...
Neil Di Salvo, Michela Maffi, Mario Lima, Di Salvo, Neil, Maffi, Michela, Lima, Mario   +5 more
core   +1 more source

Digital Healthy Aging in China: Current Landscape and the Way Forward

Health Care Science, EarlyView.
This review illustrates China's journey toward digital healthy aging, navigating the challenges of population aging through national strategies and innovative digital technologies to enable integrated, personalized care for older adults. ABSTRACT China is experiencing rapid population aging, which poses increasing challenges for healthcare and social ...
Yingpeng Qiu, Han Yao, Ping Ren, Xueqing Tian, Xuefei Gu   +4 more
wiley   +1 more source

Prediction of survival and analysis of prognostic factors for patients with AFP negative hepatocellular carcinoma: a population-based study

BMC Gastroenterology
Purpose Hepatocellular carcinoma (HCC) has a poor prognosis, and alpha-fetoprotein (AFP) is widely used to evaluate HCC. However, the proportion of AFP-negative individuals cannot be disregarded.
Chengyu Liu, Zikang Li, Zhilei Zhang, Jinlong Li, Congxi Xu, Yuming Jia, Chong Zhang, Wuhan Yang, Wenchuan Wang, Xiaojuan Wang, Kuopeng Liang, Li Peng, Jitao Wang   +12 more
doaj   +1 more source

Dual Portal Hypertension in Hepatic Tuberculosis: A Case Report

GE: Portuguese Journal of Gastroenterology
Background: Hepatic tuberculosis in itself is a rare condition, and that causing portal hypertension is even rarer. We present a unique clinical scenario of portal hypertension in a 64-year-old woman, with tuberculosis causing both sinusoidal ...
Amal Joseph, Prajob Geevarghese Prasad, Jeby Jacob, Harikumar Nair   +3 more
doaj   +1 more source

Portal hypertensive biliopathy [PDF]

Gut, 2006
Extrahepatic portal venous obstruction (EHPVO) is a common cause of portal hypertension in the developing countries, and constitutes up to 40% of all patients with portal hypertension.1,2 EHPVO is a common cause of major upper-gastrointestinal bleeding among children.2–4 The most common presentation in children is well-tolerated variceal bleeding and ...
Radha K, Dhiman, Arunanshu, Behera, Yogesh K, Chawla, Jang B, Dilawari, Sudha, Suri   +4 more
openaire   +2 more sources