Results 111 to 120 of about 9,287,329 (300)

Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization

iMetaOmics, EarlyView.
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao, Hang You, Zongyi Liu, Yong Sun, Yu Zhang, Li Wei, Ning Ling, Hong Ren, Shiying Li, Peng Hu, Mingli Peng   +10 more
wiley   +1 more source

Portal Hypertension—Noninvasive Multiparametric Ultrasound‐Based Criteria and Measurements

Portal Hypertension & Cirrhosis
Portal hypertension, the most common complication in liver cirrhosis, is characterized by a pathologic increase in portal venous pressure. Portal hypertension is defined as a pressure gradient greater than 5 mmHg between the portal vein and the inferior ...
Kathleen Möller, Riyad Abu El Hija, Xiaolong Qi, Christian Jenssen, Sven Mutze, Burkhard Möller, Benjamin Misselwitz, Christoph F. Dietrich   +7 more
doaj   +1 more source

Ultrasound and Doppler examination capabilities in adult portal hypertension type definition

Patologìâ, 2015
Early portal hypertension type diagnostics is an ultimate factor concerning kind and tactics of treatment. Aim. To objectify ultrasound examination capabilities, portal hemodynamics were studied in 97 patients using impulse and color doppler ...
N. V. Tumanskaya, A. S. Tugushev, E. S. Barskaya, А. А. Fedusenko, E. G. Nordio   +4 more
doaj   +1 more source

Hepatic sinusoidal obstruction syndrome and the search for a modifiable endothelial state

iMeta, EarlyView.
Pyrrolizidine alkaloid (PA) exposure, haematopoietic stem cell transplantation (HSCT), and repeated oxaliplatin treatment provide distinct contexts for sinusoidal endothelial injury, with differing mechanisms and courses. Oxaliplatin‐associated abnormalities may resolve or persist. Illustrated features are conceptual, not validated clinical stages or a
Ziming Zhao, Zijun Zhang, Fengling Liu, Haolu Wang, Di Yu, Chuanrui Xu, Xin Chen, Yang Xiao, Qing Yu, Qianrong Xiong, Eric C.H. Lai, Qingyi Tong, Xiaoping Chen, Yonghui Zhang   +13 more
wiley   +1 more source

Clinical Manifestations of Portal Hypertension

International Journal of Hepatology, 2012
The portal hypertension is responsible for many of the manifestations of liver cirrhosis. Some of these complications are the direct consequences of portal hypertension, such as gastrointestinal bleeding from ruptured gastroesophageal varices and from ...
Said A. Al-Busafi, Julia McNabb-Baltar, Amanda Farag, Nir Hilzenrat   +3 more
doaj   +1 more source

Surgical Considerations in Portal Hypertension. [PDF]

This review provides an in-depth exploration of portal hypertension (PH) and its implications in various surgical procedures. The prevalence of clinically significant PH is 50% to 60% in compensated cirrhosis and 100% in decompensated cirrhosis.
Berzigotti, Annalisa, Ma, Ann Thu, Sapisochin, Gonzalo, Li, Zhihao, Choi, Woo Jin, Gaviria, Felipe, Magyar, Christian Tibor Josef   +6 more
core   +1 more source

Laparoscopic Resection of Caudate Lobe Liver Tumors in Clinical Practice

iNew Medicine, EarlyView.
ABSTRACT The caudate lobe (Couinaud segment I), owing to its deep location in the posterosuperior liver, intimate encirclement by the inferior vena cava (IVC), and close adjacency to the hepatic hilum and major hepatic veins, presents a formidable anatomical challenge for resection.
Dingde Ye, Wenjie Zhang, Qiaoyu Liu, Beicheng Sun, Qingxiang Xu   +4 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Hepatic Sinusoidal Obstruction Syndrome Induced by Pyrrolizidine Alkaloids: Mechanistic Insights, Emerging Biomarkers, and Therapeutic Innovations

iNew Medicine, EarlyView.
ABSTRACT Hepatic sinusoidal obstruction syndrome (HSOS) is a microcirculatory disorder of the liver that poses a serious threat to human health. Pyrrolizidine alkaloids (PAs), a class of toxins widely found in plants, are often ingested accidentally and are one of the major causes of HSOS.
Fumin Zhang, Cheng Zhu, Xingyu Li, Yaoling Zhu, Domingo Antonio Sánchez Martínez, Ying Dai, Lifeng Guo, Derun Kong   +7 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source