Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Harnessing bacterial extracellular vesicles for bone and cartilage organoids
This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu +8 more
wiley +1 more source
Pulmonary Hypertension Classification Revisited: Actionable Simplicity vs Real-World Complexity. [PDF]
Albulushi A, Al Rashdi T, Al-Farhan H.
europepmc +1 more source
Gutter Rotation Technique for Percutaneous Ipsilateral Retrieval of a Ruptured SAPIEN‐3 Balloon
ABSTRACT Balloon rupture during transcatheter aortic valve replacement (TAVR) with balloon‐expandable valves is a rare but potentially serious complication that may result in incomplete valve expansion, difficult device retrieval, and vascular injury.
Anne Venkata Ganeshkumar +5 more
wiley +1 more source
Novel cardiovascular magnetic resonance imaging biomarkers to track response to treatment including Sotatercept in a patient with idiopathic pulmonary arterial hypertension: a case report. [PDF]
Castiglione A +3 more
europepmc +1 more source
ABSTRACT Background Acquired aseptic intracardiac communications (AICCs) are rare but clinically relevant structural complications following transcatheter aortic valve implantation (TAVI), typically resulting from mechanical injury to the aortic annulus, interventricular septum, or adjacent structures.
Geza Fontos +6 more
wiley +1 more source
Sodium-Glucose Cotransporter-2 Inhibitors in World Health Organization Group 1 Pulmonary Arterial Hypertension: A REVEAL Lite 2-Matched Cohort With Time-Varying Exposure Analysis. [PDF]
Hafez A +15 more
europepmc +1 more source
Biventricular Pressure‐Volume Loop Analysis in an LVAD Patient Optimized With Impella RP Flex
ABSTRACT Right ventricular (RV) failure after left ventricular assist device (LVAD) implantation is a serious complication which may necessitate temporary mechanical support in refractory cases. Here we describe a 63‐year‐old man with end‐stage ischemic cardiomyopathy and severe combined pre‐ and post‐capillary pulmonary hypertension who developed ...
Sara S. Inglis +3 more
wiley +1 more source
Dasatinib and Pulmonary Arterial Hypertension: When Cardio-Oncology Meets the Pulmonary Circulation. [PDF]
Sreedhara K +2 more
europepmc +1 more source
ABSTRACT Failure of true‐lumen re‐entry after subintimal wire passage is a well‐recognized limitation of endovascular treatment for external iliac artery (EIA) chronic total occlusions (CTO). We report a 73‐year‐old woman with severe limb ischemia and a prior failed endovascular attempt who underwent hybrid left common femoral artery (CFA ...
Bibhas Amatya, Dipankar Mukherjee
wiley +1 more source

