Results 31 to 40 of about 349,993 (124)
Long-term oxygen therapy in precapillary pulmonary hypertension – SOPHA study
Scientific ReportsCurrent guidelines recommend oxygen (O2) supplementation in patients with pulmonary hypertension (PH), despite scarce data on long-term O2 therapy (LTOT).
Nicola Benjamin +7 more
doaj +1 more source
Deep learning automated quantification of lung disease in pulmonary hypertension on CT pulmonary angiography: A preliminary clinical study with external validation [PDF]
arXiv, 2023 Purpose: Lung disease assessment in precapillary pulmonary hypertension (PH) is essential for appropriate patient management. This study aims to develop an artificial intelligence (AI) deep learning model for lung texture classification in CT Pulmonary Angiography (CTPA), and evaluate its correlation with clinical assessment methods.
arxiv
Nitric oxide activates AMPK by modulating PDE3A in human pulmonary artery smooth muscle cells
Physiological Reports, 2020 Phosphodiesterase 3 (PDE3), of which there are two isoforms, PDE3A and PDE3B, hydrolyzes cAMP and cGMP—cyclic nucleotides important in the regulation of pulmonary vascular tone.
Julie Dillard +4 more
doaj +1 more source
Canadian Respiratory Journal, 2017 Background. Recent studies have reported that obstructive sleep apnea (OSA) patients present alterations in right ventricular (RV) structure and function. However, large randomized controlled trials evaluating the impact of OSA on the right ventricle are
Abdirashit Maripov +8 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 Cor triatriatum sinister is a rare congenital anomaly characterized by the left-sided triatrial form of the heart. Diverse theories have been proposed regarding its formation, and the failure of incorporation of the common pulmonary vein into the left ...
I-Hsin Tai +14 more
doaj +1 more source
Noninvasive Estimation of Mean Pulmonary Artery Pressure Using MRI, Computer Models, and Machine Learning [PDF]
arXiv, 2023 Pulmonary Hypertension (PH) is a severe disease characterized by an elevated pulmonary artery pressure. The gold standard for PH diagnosis is measurement of mean Pulmonary Artery Pressure (mPAP) during an invasive Right Heart Catheterization. In this paper, we investigate noninvasive approach to PH detection utilizing Magnetic Resonance Imaging ...
arxiv
ERJ Open Research, 2020 Background Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, progressive vascular disease with poor prognosis if left untreated. This study aims to assess the patient characteristics, treatment approach and clinical and survival outcomes ...
Abdullah M. Aldalaan +8 more
doaj +1 more source
Sensitivity analysis and uncertainty quantification of 1D models of the pulmonary circulation [PDF]
, 2018 This study combines a one-dimensional (1D) model with micro-CT imaging and hemodynamic data to quantify uncertainty of flow and pressure predictions in the pulmonary arteries in a control and hypoxia induced hypertensive mouse. We use local and global sensitivity and correlation analysis to determine parameters that can be inferred from the model and ...
arxiv +1 more source
European Respiratory ReviewPulmonary hypertension (PH) is highly prevalent in patients with interstitial lung disease (ILD) and is associated with increased morbidity and mortality.
Alexandra Arvanitaki +5 more
doaj +1 more source
A Multiscale Framework for Defining Homeostasis in Distal Vascular Trees: Applications to the Pulmonary Circulation [PDF]
arXiv, 2020 Coupling hemodynamics with vessel wall growth and remodeling (G&R) is crucial for understanding pathology at distal vasculature to study progression of incurable vascular diseases, such as pulmonary arterial hypertension. The present study is the first modeling attempt that focuses on defining homeostatic baseline values in distal pulmonary vascular ...
arxiv