Results 31 to 40 of about 713,634 (281)

Angiotensin II‐induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor‐alpha type 1 receptor

open access: yesPhysiological Reports, 2021
In hypertension induced by angiotensin II (AngII) administration with high salt (HS) intake, intrarenal angiotensinogen (AGT) and tumor necrosis factor‐alpha (TNF‐α) levels increase.
Dewan S. A. Majid   +4 more
doaj   +1 more source

Blood pressure and indices of glomerular filtration area in hypertensive and normotensive Prague rats [PDF]

open access: yes, 2000
The involvement of the kidney in the pathogenesis of hypertension has long been recognised, although the specific renal mechanisms underlying this phenomenon are still unknown.
Davis, J. M., Hellmann, H., Thurau, K.
core   +1 more source

Not all that is red is blood: a curious case of chromaturia

open access: yesClinical Case Reports, 2018
Key Clinical Message Hydroxocobalamin causes reddish discoloration of the urine, mimicking hematuria. Clinicians should be aware of this common side effect of the rarely used drug to prevent unnecessary consultations and work‐up. Additional benign causes
Abhilash Koratala   +2 more
doaj   +1 more source

Know your patients’ history; spleno-renal infarction as a presentation of infective endocarditis

open access: yesClinics and Practice, 2017
Bacterial endocarditis is an infection of the endothelial surface of the heart, including heart valves and is potentially life threatening. Antibiotic prophylaxis is indicated prior to invasive procedures in patients with certain high-risk cardiac ...
Abhilash Koratala   +2 more
doaj   +1 more source

An 88‐year‐old patient with ADPKD: underscoring the importance of risk factor modification

open access: yesClinical Case Reports, 2017
Key Clinical Message The mean age of onset of end‐stage renal disease (ESRD) in autosomal dominant polycystic kidney disease (ADPKD) is between 56 and 69.
Abhilash Koratala   +2 more
doaj   +1 more source

Metformin does not slow cyst growth in the PCK rat model of polycystic kidney disease

open access: yesPhysiological Reports, 2023
Metformin (MET) has the potential to activate p‐AMPK and block mTORC1‐induced proliferation of tubular cells in PKD kidneys. The aim of this study was to determine the effects of MET on cyst growth, kidney function, AMPK and mTOR signaling, and lactate ...
Ozgur A. Oto   +6 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Drug treatment of hypertension: focus on vascular health [PDF]

open access: yes, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C.   +2 more
core   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas   +7 more
wiley   +1 more source

Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice

open access: yesCell Reports, 2016
The kidney has a tremendous capacity to regenerate following injury, but factors that govern this response are still largely unknown. We isolated cells from mouse kidneys with high proliferative and multi-lineage differentiation capacity.
Hyun Mi Kang   +5 more
doaj   +1 more source

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