Results 71 to 80 of about 713,403 (256)

Mediators of Inflammation in Acute Kidney Injury

Mediators of Inflammation, 2009
Acute kidney injury (AKI) remains to be an independent risk factor for mortality and morbidity. Inflammation is now believed to play a major role in the pathopathophysiology of AKI.
Ali Akcay, Quocan Nguyen, Charles L. Edelstein   +2 more
doaj   +1 more source

Human Kidney Tubule-Specific Gene Expression Based Dissection of Chronic Kidney Disease Traits

EBioMedicine, 2017
Chronic kidney disease (CKD) has diverse phenotypic manifestations including structural (such as fibrosis) and functional (such as glomerular filtration rate and albuminuria) alterations.
Pazit Beckerman, Chengxiang Qiu, Jihwan Park, Nora Ledo, Yi-An Ko, Ae-Seo Deok Park, Sang-Youb Han, Peter Choi, Matthew Palmer, Katalin Susztak   +9 more
doaj   +1 more source

Dietary interventions to contrast the onset and progression of diabetic nephropathy. a critical survey of new data [PDF]

, 2017
This article is a critical overview of recent contributions on the dietary corrections and the foods that have been claimed to delay or hinder the onset of diabetic nephropathy (DN) and its progression to end-stage renal disease.
Iacobini, Carla, Menini, Stefano, Pesce, Carlo, Pugliese, Giuseppe   +3 more
core   +1 more source

Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration

Arthritis Care &Research, EarlyView.
Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source

Effects of sodium bicarbonate therapy on cognitive and cerebrovascular function in midlife and older adults with chronic kidney disease: a pilot randomized trial

BMC Nephrology
Introduction Metabolic acidosis may create a pathway to cognitive impairment in chronic kidney disease (CKD) by contributing to cerebrovascular dysfunction.
Fangning Gu, Zhiying You, Nell Hawkins, Rachael Reddin, Rahaf Hamour, Allison Shapiro, Christina Coughlan, Douglas Seals, Seth Furgeson, Angelina Dixon, Kristen L. Nowak, Jessica Kendrick   +11 more
doaj   +1 more source

Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]

, 2016
Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio, Barbano, Biagio, Barilaro, Giuseppe, Cianci, Rosario, Di Mario, Francesca, Gasperini, Maria Ludovica, Gigante, Antonietta, Quarta, Silvia, Romaniello, Antonella, Rosato, Edoardo   +9 more
core   +1 more source

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Not all inflammation in a renal allograft is rejection

Clinical Case Reports, 2018
Key Clinical Message High index of suspicion for adenovirus infection is required in renal graft dysfunction, especially in the setting of hematuria. Histology can mimic acute rejection, which creates a diagnostic dilemma. Tissue adenovirus immunostains,
Kawther F. Alquadan, Karl L. Womer, Alfonso H. Santos, Xu Zeng, Abhilash Koratala   +4 more
doaj   +1 more source

The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension [PDF]

, 2015
We assessed the predictive ability of selected biomarkers using N-terminal pro-brain natriuretic peptide (NT-proBNP) as the benchmark and tried to establish a multi-biomarker approach to heart failure (HF) in hypertensive patients. In 120 hypertensive
Agata Bielecka-Dabrowa, Anna Gluba-Brzózka, Campeau, Jacek Rysz, Li, Maciej Banach, Marta Michalska-Kasiczak, Małgorzata Misztal, McCullough, Ravassa, Wei   +10 more
core   +2 more sources

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source