Results 91 to 100 of about 2,757,661 (328)

Multimorbidity in bipolar disorder and under-treatment of cardiovascular disease: a cross sectional study [PDF]

, 2013
Background: Individuals with serious mental disorders experience poor physical health, especially increased rates of cardiometabolic morbidity and premature morbidity.
A Weeke, AJ Ferrari, AJ Mitchell, B Felker, B Ya-Mei, Bruce Guthrie, C Astrup, C Crump, CW Colton, Daniel J Smith, Daniel Martin, DJ Smith, E Koranyi, EH Høyer, F Angst, FG Joseph, Gary McLean, J Johnson, J Langan, JA Mackell, Julie Langan, K Barnett, LM Koran, M De Hert, M De Hert, M De Hert, M Tohen, MJ Fleury, MT Tsuang, N Myles, O Bratfos, P Vestergaard, PA Kurdyak, R Sharma, RM Weinryb, SH Han, Stewart W Mercer, T Callréus, TM Laursen, TM Laursen, U Osby, U Petterson, VMR Carstairs   +42 more
core   +3 more sources

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani, Dylan N. Wolman, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Kelsey E. Kline, Clemens M. Schirmer, Raul G. Nogueira, Alexandra R. Paul, Bradley N. Bohnstedt, Philipp Hendrix   +38 more
wiley   +1 more source

Glycocalyx Degradation in Retinal and Choroidal Capillary Endothelium in Rats with Diabetes and Hypertension [PDF]

, 2010
Endothelial glycocalyx (GCX) has been reported as a protective factor for vascular endothelial cells (VEC) in diabetes and hypertension. However, the involvement of GCX impairment in ocular vasculopathy remains unclear.
Kumase, Fumiaki, Mohri, Satoshi, Morizane, Yuki, Ohtsuka, Aiji, Ohtsuki, Hiroshi, Takasu, Ippei   +5 more
core   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Redox stress defines the small artery vasculopathy of hypertension: how do we bridge the bench-to-bedside gap? [PDF]

, 2017
Although convincing experimental evidence demonstrates the importance of vascular reactive oxygen and nitrogen species (RONS), oxidative stress, and perturbed redox signaling as causative processes in the vasculopathy of hypertension, this has not ...
Liang, Mingyu, Montezano, Augusto C., Rios, Francisco, Touyz, Rhian M., Widlansky, Michael E.   +4 more
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Association Between the Chinese Visceral Adiposity Index and Obstructive Sleep Apnoea in Hypertensive Patients with Normal-Weight: A Cross-Sectional Study

International Journal of General Medicine
Delian Zhang,1– 5,* Kangxin Cai,1– 5,* Qing Zhu,1– 5 Aliye Abulaiti,1– 5 Jing Hong,1– 5 Yingchun Wang,1– 5 Nanfang Li1– 5 1Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, 830001, People’s ...
Zhang D, Cai K, Zhu Q, Abulaiti A, Hong J, Wang Y, Li N   +6 more
doaj  

Rosiglitazone Restores Endothelial Dysfunction in a Rat Model of Metabolic Syndrome through PPARγ- and PPARδ-Dependent Phosphorylation of Akt and eNOS

PPAR Research, 2011
Vascular endothelial dysfunction has been demonstrated in metabolic syndrome (MS). Chronic administration of rosiglitazone ameliorates endothelial dysfunction through PPARγ-mediated metabolic improvements.
Zhigang Zhao, Zhidan Luo, Peijian Wang, Jing Sun, Hao Yu, Tingbing Cao, Yinxing Ni, Jing Chen, Zhencheng Yan, Daoyan Liu, Zhiming Zhu   +10 more
doaj   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

Plasma Aldosterone Elevation in Hypertensive Patients and Association with Urinary Stone Formation: A Large-Scale Population Study from Northwest China

Clinical Epidemiology
Shuaiwei Song,1– 5,* Nanfang Li,1– 5,* Di Shen,1– 5 Junli Hu,1– 5 Xintian Cai,1– 5 Qing Zhu,1– 5 Yingying Zhang,1– 5 Rui Ma,1– 5 Pan Zhou,1– 5 Zhiqiang Zhang,1– 5 Wen Jiang,1– 5 Jing Hong1– 5 1Hypertension Center of People’s Hospital of ...
Song S, Li N, Shen D, Hu J, Cai X, Zhu Q, Zhang Y, Ma R, Zhou P, Zhang Z, Jiang W, Hong J   +11 more
doaj