Results 11 to 20 of about 2,600,943 (336)

Hypertension [PDF]

Nature Reviews Disease Primers, 2018
Systemic arterial hypertension is the most important modifiable risk factor for all-cause morbidity and mortality worldwide and is associated with an increased risk of cardiovascular disease (CVD). Fewer than half of those with hypertension are aware of their condition, and many others are aware but not treated or inadequately treated, although ...
Oparil, Suzanne, Acelajado, Maria Czarina, Bakris, George L., Berlowitz, Dan R., Cífková, Renata, Dominiczak, Anna F., Grassi, Guido, Jordan, Jens, Poulter, Neil R., Rodgers, Anthony, Whelton, Paul K.   +10 more
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Sodium‐Glucose Cotransporter 2 Inhibitor Canagliflozin Antagonizes Salt‐Sensitive Hypertension Through Modifying Transient Receptor Potential Channels 3 Mediated Vascular Calcium Handling

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Salt‐sensitive hypertension is highly prevalent and associated with cardiorenal damage. Large clinical trials have demonstrated that SGLT2 (sodium‐glucose cotransporter 2) inhibitors exert hypotensive effect and cardiorenal protective benefits
Yu Zhao, Li Li, Zongshi Lu, Yingru Hu, Hexuan Zhang, Fang Sun, Qiang Li, Chengkang He, Wentao Shu, Lijuan Wang, Tingbing Cao, Zhidan Luo, Zhencheng Yan, Daoyan Liu, Peng Gao, Zhiming Zhu   +15 more
doaj   +1 more source

Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease

Cardiovascular Diabetology, 2022
Background Altered adipokine secretion in dysfunctional adipose tissue facilitates the development of atherosclerotic diseases including lower extremity peripheral artery disease (PAD).
Mei You, Yushuang Liu, Bowen Wang, Li Li, Hexuan Zhang, Hongbo He, Qing Zhou, Tingbing Cao, Lijuan Wang, Zhigang Zhao, Zhiming Zhu, Peng Gao, Zhencheng Yan   +12 more
doaj   +1 more source

Hypertension [PDF]

Global Advances in Health and Medicine, 2012
Hypertension is responsible for roughly one-in-six adult deaths annually in the United States and is associated with five of the top nine causes of death.1 Ten trillion dollars is the estimated annual cost worldwide of the direct and indirect effects of hypertension.2,3 In the U.S.
Fitzgerald, Kara, LePine, Todd
openaire   +2 more sources

Poor sleep quality is negatively associated with low cognitive performance in general population independent of self-reported sleep disordered breathing

BMC Public Health, 2022
Background Sleep disordered breathing (SDB) plays a significant role in both sleep quality and cognition and whether it has an impact on the relationship between above two factors remains to be clear.
Zhongrong Wang, Mulalibieke Heizhati, Lin Wang, Mei Li, Zhikang Yang, Mengyue Lin, Reyila Abudereyimu, Jing Hong, Wenbo Yang, Ling Yao, Shasha Liu, Junli Hu, Nanfang Li   +12 more
doaj   +1 more source

HYPERTENSION: Essential hypertension: the heart and hypertension [PDF]

Heart, 2001
The heart and hypertension are intimately linked. Hypertension predisposes to coronary heart disease, myocardial hypertrophy, and cardiac dysfunction. Other organs and systems are also important in hypertension but this article concentrates on the effect of hypertension on the heart.
K E Berkin, S G Ball
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Korea hypertension fact sheet 2018

Clinical Hypertension, 2018
Background The Korea Hypertension Fact Sheet 2018 aims to overview the magnitude and management status of hypertension, and their trends in Korea. Methods The Hypertension Epidemiology Research Group analyzed the 1998–2016 Korea National Health and ...
The Korean Society Hypertension (KSH), Hypertension Epidemiology Research Working Group, Hyeon Chang Kim, Myeong-Chan Cho   +3 more
doaj   +1 more source

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]

, 2018
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J., Petrie, John R., Touyz, Rhian M.   +2 more
core   +1 more source

Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans [PDF]

, 2017
Compelling evidence for the inherited nature of essential hypertension has led to extensive research in rats and humans. Rats have served as the primary model for research on the genetics of hypertension resulting in identification of genomic regions ...
Allbutt TC, Bina Joe, Biron P, Biron P, Bright R, Cook HW, Dublin LI, Dublin LI, Dupont J, Esunge PM, Felts JH, Garrod AE, Garrod AE, Garrod AE, Hamilton M, Hamilton M, Hamilton M, Joe B, Koffler M, Korner PI, Kuijpers MH, Lee YH, Lewis O, Markel’ AL, Matsukawa N, Mo R, Ohno Y, Pickering GW, Pravenec M, Sandosh Padmanabhan, Schlager G, Shear CL, Shiozawa M, Smolarek I, Zhang Y   +34 more
core   +1 more source

Clinical Characteristics of Target Organ Damage in Primary Aldosteronism with or without Metabolic Syndrome

Journal of Diabetes Research, 2022
The aim of this study is to investigate the prevalence of metabolic disorders in patients with primary aldosteronism (PA) and target organ damage (TOD) in different subtypes of patients with PA with or without metabolic syndrome (MS).
Xiaona Bu, Fang Sun, Hexuan Zhang, Xiaoli Liu, Zhigang Zhao, Hongbo He, Yingsha Li, Zhencheng Yan, Zhiming Zhu   +8 more
doaj   +1 more source