Glucocorticoids for treating paediatric pulmonary hypertension: A novel use for a common medication [PDF]
, 2017 Laboratory investigations have shown the role of inflammation in the pathogenesis of pulmonary hypertension and improvement after anti-inflammatory drugs.
Aggarwal, Manish, Grady, Ronald M
core +2 more sources
Genetically Encoded Calcium Indicators: A New Tool in Renal Hypertension Research [PDF]
, 2019 Hypertension is ranked as the third cause of disability-adjusted life-years. The percentage of the population suffering from hypertension will continue to increase over the next years.
Schleifenbaum, Johanna, Zhong, Cheng
core +1 more source
Urinary Podocyte Excretion Predicts Urinary Protein Selectivity and Renal Prognosis
International Journal of Nephrology, 2022 Background. Urinary podocyte excretion is related to a reduction in glomerular podocyte numbers, glomerulosclerosis, and urinary protein selectivity.
Makoto Abe +4 more
doaj +1 more source
Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans [PDF]
, 2017 Compelling evidence for the inherited nature of essential hypertension has led to extensive research in rats and humans. Rats have served as the primary model for research on the genetics of hypertension resulting in identification of genomic regions ...
Allbutt TC +34 more
core +1 more source
Increased circulating ANG II and TNF-α represents important risk factors in obese Saudi adults with hypertension irrespective of diabetic status and BMI [PDF]
, 2012 Central adiposity is a significant determinant of obesity-related hypertension risk, which may arise due to the pathogenic inflammatory nature of the abdominal fat depot.
A Berrington de Gonzalez +63 more
core +5 more sources
The Childhood Role in Development of Primary Hypertension. [PDF]
, 2018 Primary hypertension is not just an adult disorder. Current US population data on children and adolescents demonstrate a prevalence of elevated blood pressure (BP) and hypertension combined of over 10%.
Falkner, Bonita
core +2 more sources
International Journal of Endocrinology, 2021 Context. Failure of plasma aldosterone suppression during the saline infusion test (SIT) confirms primary aldosteronism (PA); recommendations for diagnostic strategies are currently controversial in the case of an inconclusive test result with a post-SIT
Munire Adilijiang +7 more
doaj +1 more source
Androgens and Hypertension in Men and Women: a Unifying View. [PDF]
, 2017 This review was designed to revaluate the androgen role on the mechanisms of hypertension and cardiovascular risks in both men and women. Sex steroids are involved in the regulation of blood pressure, but pathophysiological mechanism is not well ...
Carmina, E. 4. +4 more
core +1 more source
Diabetology & Metabolic Syndrome, 2018 Background Although multidisciplinary treatment is recommended for type 2 diabetes mellitus and hypertension (HTN), there is a lack of scientific literature supporting the hypothesis of extending this treatment strategy to patients with both diabetes and
Thiago Veiga Jardim +11 more
doaj +1 more source
Assessment of sublingual microcirculation for the screening of diabetic nephropathy
Diabetology & Metabolic Syndrome, 2022 Objective To investigate the potential of employing sublingual microcirculation as an early noninvasive screening technique for diabetic nephropathy (DN).
Qiang Li +10 more
doaj +1 more source