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ABC of hypertension: The pathophysiology of hypertension

BMJ, 2001
There is still much uncertainty about the pathophysiology of hypertension. A small number of patients (between 2% and 5%) have an underlying renal or adrenal disease as the cause for their raised blood pressure. In the remainder, however, no clear single identifiable cause is found and their condition is labelled “essential hypertension”.
Gregory Y.H. Lip, Eoin O'Brien, Gareth Beevers   +2 more
openaire   +4 more sources

The Childhood Role in Development of Primary Hypertension. [PDF]

, 2018
Primary hypertension is not just an adult disorder. Current US population data on children and adolescents demonstrate a prevalence of elevated blood pressure (BP) and hypertension combined of over 10%.
Falkner, Bonita
core   +2 more sources

Comparação de critérios diagnósticos de insuficiência renal aguda em cirurgia cardíaca

Arquivos Brasileiros de Cardiologia, 2013
FUNDAMENTO: Há grande controvérsia quanto ao diagnóstico de Insuficiência Renal Aguda (IRA), existindo mais de 30 diferentes definições. OBJETIVO: Avaliar a incidência e os fatores de risco para desenvolvimento de IRA no pós-operatório de cirurgia ...
Márcio Campos Sampaio, Carlos Alberto Gonçalves Máximo, Carolina Moreira Montenegro, Diandro Marinho Mota, Tatiana Rocha Fernandes, Antonio Carlos Mugayar Bianco, Celso Amodeo, Antonio Carlos Cordeiro   +7 more
doaj   +1 more source

Genetically Encoded Calcium Indicators: A New Tool in Renal Hypertension Research [PDF]

, 2019
Hypertension is ranked as the third cause of disability-adjusted life-years. The percentage of the population suffering from hypertension will continue to increase over the next years.
Schleifenbaum, Johanna, Zhong, Cheng
core   +1 more source

Residues R177 and S178 of the human Na+/H+ antiporter NHA2 are involved in its inhibition by the flavonoid phloretin

FEBS Letters, Volume 599, Issue 6, Page 901-911, March 2025.
The human Na+/H+ antiporter NHA2 transports Na+ or Li+ in exchange for protons across cell membranes, and its dysfunction results in various pathologies, e.g., fertility disorders, hypertension, or diabetes. This work provides the molecular characterization of interactions of NHA2 with its specific inhibitor phloretin, which can be helpful for the ...
Olga Zimmermannova, Martin Kubeš, Tereza Przeczková, Gal Masrati   +3 more
wiley   +1 more source

Hypertension

South African Family Practice, 2011
No Abstract.
openaire   +3 more sources

Sources of dietary protein and risk of hypertension in a general Dutch population [PDF]

, 2012
Evidence suggests a small beneficial effect of dietary protein on blood pressure (BP), especially for plant protein. We examined the relationship between several types of dietary protein (total, plant, animal, dairy, meat and grain) and the risk of ...
Altorf-van der Kuil, W., Boer, J.M.A., Engberink, M.F., Geleijnse, J.M., Verschuren, W.M.M.   +4 more
core   +2 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

The use of statins are associated with an increased risk of new-onset diabetes in patients with hypertension and obstructive sleep apnoea, a longitudinal study

Diabetology & Metabolic Syndrome
Background Statins, a kind of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, are first-line cholesterol-lowering drugs that are widely used in the primary and secondary prevention of coronary atherosclerotic heart disease (CAD ...
Hui Wang, Mulalibieke Heizhati, Nanfang Li, Lin Gan, Ling Yao, Mei Li, Li Cai, Xiufang Li, Xiayire Aierken, Dan Yu, Miaomiao Liu, Adalaiti Maitituersun, Qiaolifanayi Nuermaimaiti, Aketilieke Nusufujiang, Jing Hong   +14 more
doaj   +1 more source

Barriers to Access to Treatment for Hypertensive Patients in Primary Health Care of Less Developed Northwest China: A Predictive Nomogram

International Journal of Hypertension, 2021
Background. This study aims to evaluate the risk factors associated with untreated hypertension and develop and internally validate untreated risk nomograms in patients with hypertension among primary health care of less developed Northwest China ...
Lin Wang, Mulalibieke Heizhati, Xintian Cai, Mei Li, Zhikang Yang, Zhongrong Wang, Reyila Abudereyimu, Nanfang Li   +7 more
doaj   +1 more source