Results 91 to 100 of about 405,904 (181)

Aiding the Diagnosis of Diabetic and Hypertensive Retinopathy Using Artificial Intelligence-Based Semantic Segmentation

Journal of Clinical Medicine, 2019
Automatic segmentation of retinal images is an important task in computer-assisted medical image analysis for the diagnosis of diseases such as hypertension, diabetic and hypertensive retinopathy, and arteriosclerosis.
Muhammad Arsalan, Muhammad Owais, T. Mahmood, S. Cho, K. Park   +4 more
semanticscholar   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Metabolic Risk Predictors Associated With the Onset of Vascular Complications Among Patients With Type 2 Diabetes in Zambia: A Retrospective Statistical Modeling Study

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Diabetes mellitus contributes significantly to the global disease burden, affecting approximately 537 million adults worldwide, with over 75% residing in low and middle‐income countries (LMICs). In Zambia, evidence on metabolic predictors of vascular complications among patients with Type 2 Diabetes Mellitus (T2DM) is ...
Gunet Mwalungali, Welani Chilengwe, John Mwaba, Eustarckio Kazonga, Richard Mutemwa, Martin Kampamba, Larry Mweetwa, Audrey Hamachila, Christine Mutati, Soddy Munsaka, Jimmy Hangomma, Rachel Milomba, Mordecai Malambo, Chanda Chisunka, Nthele Mzaza, Patience Buumba, Chota Bwalya, Pamela Mwansa   +17 more
wiley   +1 more source

A Cohort Study on Incidence and Factors Associated With Adverse Drug Reactions of Enalapril in Lusaka, Zambia

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Angiotensin‐converting enzyme inhibitors (ACEIs) are widely prescribed but are associated with adverse drug reactions (ADR), including angioedema, which is typically reported in 0.1%–0.7%. Data from sub‐Saharan Africa are limited. This study aimed to estimate the incidence and risk factors of enalapril‐associated ADRs in a Zambian cohort, with
Ntemena Yikon'a, Ngosa Mumba, Sarah Pedretti, Helen Hoenck, Jonathan Peter, Owen Ngalamika   +5 more
wiley   +1 more source

Cerebral Small Vessel Disease Associated with Subclinical Vascular Damage Indicators in Asymptomatic Hypertensive Patients

Behavioral Sciences, 2019
Background: Cerebral small vessel disease (CSVD) is frequent in patients with cardiovascular risk factors including arterial hypertension, and it is associated with vascular damage in other organs and the risk of stroke, cognitive impairment, and ...
Zenaida Milagros Hernández-Díaz, Marisol Peña-Sánchez, Alina González-Quevedo, Sergio González-García, Paula Andrea Arias-Cadena, Marta Brown-Martínez, Mélany Betancourt-Loza, Anay Cordero-Eiriz   +7 more
doaj   +1 more source

Cardiovascular Autonomic Neuropathy and Indices of Heart Failure in Type 2 Diabetes: The CANCAN Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9356-9366, October 2026.
ABSTRACT Aim To quantify the association between cardiovascular autonomic neuropathy (CAN) and heart failure (HF) in individuals with type 2 diabetes (T2D). Materials and Methods Two hundred T2D individuals were recruited from two Danish outpatient clinics between 2021–2024. CAN was defined by abnormal cardiovascular autonomic reflex test results.
Jonas R. Schaarup, Lasse Bjerg, Christian S. Hansen, Daniel R. Witte, Henrik H. Thomsen, Jesper Fleischer, Rodica Pop‐Busui, Signe T. Andersen   +7 more
wiley   +1 more source

Looking Beyond Glycaemic Control: Real‐World 12‐Month Cardiometabolic and Retinopathy Outcomes Following Omnipod 5 Initiation in People With Type 1 Diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9166-9177, October 2026.
ABSTRACT Aims To evaluate the real‐world effectiveness, safety, and tolerability of the Omnipod 5 hybrid closed‐loop system in adults with type 1 diabetes (T1D) with a novel focus on cardiometabolic markers alongside diabetic eye disease and renal function. Methods A single‐centre, retrospective analysis of adults with T1D using Omnipod 5 was conducted.
Eleanor McNally, Iona Goodman, Rebecca Morris, John Maliekkal, Dalha Saeed, Hao Wei Tan, Simon Berry, Jackie Elliott, Ahmed Iqbal   +8 more
wiley   +1 more source

Case report: The role of hypertension retinopathy graduation in the management of systemic cardiovascular disease

Journal of Family Medicine and Primary Care
Moderate to severe hypertensive retinopathies are more likely to correlate with uncontrolled blood pressure in all ages. Mild microvascular changes are expected with natural aging and are therefore more concerning in patients younger than 40.
Kathryn Kosteva, Evan J Kaufman, Alicia Kinch   +2 more
doaj   +1 more source

Extracellular CIRP Dysregulates Microglial Efferocytosis in Acute Ischemic Stroke via the TLR4/miR‐155/MafB Axis

Advanced Science, Volume 13, Issue 53, 24 September 2026.
eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin, Dilara Aylar, Archna Sharma, Ping Wang   +3 more
wiley   +1 more source

Hypertensive retinopathy and associated factors among nondiabetic chronic kidney disease patients seen at a tertiary hospital in Tanzania: a cross-sectional study

International Journal of Nephrology and Renovascular Disease, 2019
Pilly Chillo,1 Ame Ismail,1 Anna Sanyiwa,2 Paschal Ruggajo,1 Appolinary Kamuhabwa31Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; 2Department of Ophthalmology, Muhimbili University of Health ...
Chillo P, Ismail A, Sanyiwa A, Ruggajo P, Kamuhabwa A   +4 more
doaj