Results 81 to 90 of about 29,180 (209)

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Cicletanine and Hypertensive Retinopathy

Ophthalmic Research, 1990
The aim of the present work was to study the activity of a new antihypertensive drug, a synthetic furopyridine, cicletanine, upon hypertensive morphological lesions of the retina. The stroke-prone spontaneously hypertensive rat strain (SHR-SP), known to develop hypertensive retinopathy, was a particularly suitable material in this view.
M M, Ruchoux, M T, Droy-Lefaix, F, Bakri, J, Guillemain, P, Ruchoux, A, Autret   +5 more
openaire   +2 more sources

Early Stage of Hypertensive Retinopathy; Is It Really Important?

Turkish Journal of Nephrology, 2019
OBJECTIVE: To investigate the relationship between early stage hypertensive retinopathy (HTRP) and endothelial dysfunction (ED) in atherogenesis.
Murat KARAMAN, Seyid Ahmet AY, Yalçın BOZKURT, Ümit YOLCU, Ömer KURT, Fatih BULUCU, Levent YAMANEL, Kenan SAĞLAM, Halil YAMAN   +8 more
doaj  

Screening, diagnosis and treatment of hypertension in obese children: an international policy comparison [PDF]

, 2017
Hypertension in obese children may require a different diagnostic and treatment approach from that for children with secondary hypertension, yet there is neither consensus nor a clear guideline. The aim of this study was to assess how obese children with
Chinapaw, M.J.M. (Mai), Groothoff, J.W. (Jaap W.), Kist-Van Holthe, J.E. (Joana), Nauta, J. (Jeroen), Verheul, J. (Jelle), Wirix, A.J.G.   +5 more
core   +1 more source

Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes

Experimental Physiology, EarlyView.
Abstract We tested whether older adults with well‐controlled type 2 diabetes or hypertension, compared with age‐matched adults without chronic disease, exhibit greater intestinal damage, microbial translocation and inflammation during exertional heat stress.
Ben J. Lee, Tessa R. Flood, Sophie L. Russell, James J. McCormick, Kelli E. King, Naoto Fujii, Tatsuro Amano, Sean Notley, Glen P. Kenny   +8 more
wiley   +1 more source

Quality of care in patients with diabetic kidney disease in Asia: The Joint Asia Diabetes Evaluation (JADE) Registry [PDF]

, 2016
Aims: Diabetic kidney disease independently predicts cardiovascular disease and premature death. We examined the burden of chronic kidney disease (CKD, defined as an estimated GFR < 60 ml/min/1.73 m2) and quality of care in a cross-sectional survey of ...
Chan, J. C., Chan, W. B., Chow, C. C., Do, T. Q., Duran, M., Guo, X., Hong, E. G., Jia, W., Kong, A. P., Li, W., Li, X., Luk, A. O., Ma, R. C., Mukhopadhyay, M., Nguyen, T. K., Ojha, A. K., Ozaki, R., Sheu, W., So, W. Y., Sobrepena, L., Toledo, R. M., Tong, P. C., Tsang, C. C., Weng, J., Yang, W., Yoon, K. H., Zhang, Y.   +26 more
core   +1 more source

Sodium thiosulfate treatment rescues hyperglycaemia‐induced pronephros damage in zebrafish by upregulating nitric oxide signalling

The Journal of Physiology, EarlyView.
Abstract figure legend Sodium thiosulfate (STS) rescues the pronephros phenotype of pdx1 morphants through compensatory upregulation of nitric oxide (NO) metabolism. Zebrafish larvae injected with a control morpholino show the typical pronephros structure at 48 h post‐fertilization (hpf) with and without STS treatment.
Hannes Ott, Katrin Bennewitz, Xin Zhang, Mariia Prianichnikova, Carsten Sticht, Gernot Poschet, Jens Kroll   +6 more
wiley   +1 more source

Correction to the pathogenic alternative splicing, caused by the common GNB3 c.825C>T allele, using a novel, antisense morpholino [PDF]

, 2016
The very common GNB3 c.825C>T polymorphism (rs5443), is present in approximately half of all human chromosomes. Significantly the presence of the GNB3 825T allele has been strongly associated, with predisposition to essential hypertension ...
Lester, Douglas H., McGlinchey, Jonathan C. P., Tummala, Hemanth   +2 more
core   +3 more sources

Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment epithelial cells with hypertensive phenotype

The Journal of Physiology, EarlyView.
Abstract figure legend Circulating extracellular vesicles (EVs) derived from acebuche (ACE) oil‐ and extra virgin olive oil (EVOO)‐fed mice modulate nitric oxide (NO) metabolism in the retinal pigment epithelial cell line (ARPE19) with a hypertensive phenotype induced by angiotensin II (AngII).
Álvaro Santana‐Garrido, Claudia Reyes‐Goya, Pablo Espinosa‐Martín, Rosa M. Troya‐Toledo, Helder André, Alfonso Mate, Carmen M. Vázquez   +6 more
wiley   +1 more source

Grade III or Grade IV Hypertensive Retinopathy with Severely Elevated Blood Pressure

Western Journal of Emergency Medicine, 2012
Introduction: Hypertensive retinopathy describes a spectrum of retinal changes in patients with elevated blood pressure (BP). It is unknown why some patients are more likely to develop acute ocular end-organ damage than others with similar BP.
Amanda D Henderson, Valérie Biousse, Nancy J Newman, Cédric Lamirel, David W Wright, Beau B Bruce   +5 more
doaj