Results 201 to 210 of about 81,072 (284)

Synthesis and Application of Chitosan‐Salicylic Acid Magnetic Nanoparticles in Colon Cancer Cells

Nano Select, EarlyView.
This study reports the development of magnetic nanoparticles using chitosan as a stabilizer and conjugated with salicylic acid for colon cancer therapy. The biocompatible design enhances nanoparticle stability and enables selective toxicity against cancer cells while minimizing effects on normal cells.
Aida Ebadi, Mahla Mohammadi, Mohammad Mehdi Ebadi, Sarah Mousavi, Mohammad Mashreghi, Ali Es‐Haghi, Mohammad Ehsan Taghavizadeh Yazdi, Hossein Behmadi, Mohammad Qandalee, Carlos J. Durán‐Valle, Ignacio M. López‐Coca   +10 more
wiley   +1 more source

Ultrastructural Analysis of the Large Neuronal Perikarya in an Injured Dentate Nucleus Using an Experimental Model of Hyperthermia-Induced Convulsions: The First Qualitative and Quantitative Study. [PDF]

J Clin Med
Łotowska JM, Borowska M, Żochowska-Sobaniec M, Sendrowski K, Sobaniec-Łotowska ME.   +4 more
europepmc   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Epidemiology, Morbidity and Mortality Associated With Anesthesia in Early Life: A Subgroup Analysis of the German NEonate and Children audiT of Anesthesia pRactice IN Europe (NECTARINE) Cohort

Pediatric Anesthesia, EarlyView.
ABSTRACT Background The NEonate and Children audiT of Anesthesia pRactice IN Europe (NECTARINE) study, led by the ESAIC Clinical Trials Network, collected prospective data on 5609 children up to 60 weeks postmenstrual age undergoing 6542 anesthetic procedures across 165 centers in 31 European countries (ESAIC_CTN_NECTARINE).
Claudia Neumann, Alina Schenk, Ehrenfried Schindler, Karin Becke‐Jakob, German Nectarine Group Collaborators   +4 more
wiley   +1 more source

Modulated Electro-Hyperthermia-Induced Tumor Damage Mechanisms Revealed in Cancer Models. [PDF]

Int J Mol Sci, 2020
Krenacs T, Meggyeshazi N, Forika G, Kiss E, Hamar P, Szekely T, Vancsik T.   +6 more
europepmc   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Hyperthermia-Induced Controlled Local Anesthesia Administration Using Gelatin-Coated Iron-Gold Alloy Nanoparticles. [PDF]

Pharmaceutics, 2020
Ting CK, Dhawan U, Tseng CL, Alex Gong CS, Liu WC, Tsai HD, Chung RJ.   +6 more
europepmc   +1 more source

Treatment of pediatric epilepsy

Pediatric Investigation, EarlyView.
Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li, Tinghong Liu, Chang Liu, Jie Deng, Shijie Wu, Suhui Kuang, Xiaotong Li, Zhirong Wei, Shuli Liang   +8 more
wiley   +1 more source

Diagnosis and rescue of malignant hyperthermia induced by anesthesia during radical surgery in a cervical cancer patient using the National Remote Emergency System: A case report. [PDF]

Medicine (Baltimore)
Xiao Y, Yu R, Gu J.
europepmc   +1 more source

Evaluation of the Potential Carrier and Controlled Release of Antibiotics by Zinc, Nickel, and Cobalt Ferrite Nanoparticles Encapsulated with Silica and Functionalized with Moxifloxacin Hydrochloride

Particle &Particle Systems Characterization, EarlyView.
The study reveals the inhibitory potential of encapsulated nanoparticles functionalized with moxifloxacin hydrochloride. ABSTRACT Bacterial resistance represents a significant global health threat associated with the development of microbial resistance genes.
Amanda S. Abreu, Stéfanne R. R. Ferreira, Naiara G. Cabral, Romayne P. França, Hanstter H. A. Rezende, Richard Landers, Alexandre Pancotti   +6 more
wiley   +1 more source