Results 241 to 250 of about 79,716 (271)

Perioperative complications of focal therapy for prostate cancer: results from the GeRmAn Nationwide inpatient Data (GRAND) study

open access: yesBJU International, EarlyView.
Objective To compare the perioperative complications of the most common focal therapy (FT) modalities for prostate cancer. Patients and Methods We assessed the GeRmAn Nationwide inpatient Data (GRAND) from 2005 to 2023, provided by the Research Data Center of the Federal Bureau of Statistics. We compared perioperative outcomes of high‐intensity focused
Nikolaos Pyrgidis   +9 more
wiley   +1 more source

Novel FKBP prolyl isomerase 1A (FKBP12) ligand promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 11, Page 2466-2486, June 2025.
Background and Purpose Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with limited treatment options. ALS pathogenesis involves intricate processes within motor neurons, characterized by dysregulated Ca2+ influx and buffering in early ALS‐affected motor neurones. This study proposes the modulation of ryanodine receptors (
Laura Moreno‐Martinez   +17 more
wiley   +1 more source

HORMONAL CHANGES IN PORCINE MALIGNANT HYPERTHERMIA

open access: bronze, 1976
G.M. Hall   +3 more
openalex   +1 more source

Integrating fine‐scale behaviour and microclimate data into biophysical models highlights the risk of lethal hyperthermia and dehydration

open access: yesEcography, Volume 2025, Issue 4, April 2025.
Climate change threatens biodiversity by compromising the ability to balance energy and water, influencing animal behaviour, species interactions, distribution and ultimately survival. Predicting climate change effects on thermal physiology is complicated by interspecific variation in thermal tolerance limits, thermoregulatory behaviour and ...
Shannon R. Conradie   +6 more
wiley   +1 more source

Variants in ATP6V0C are associated with Dravet‐like developmental and epileptic encephalopathy

open access: yesEpilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a developmental and epileptic encephalopathy. Diagnosis is clinical, but ~90% of patients have pathogenic variants in SCN1A. ATP6V0C has recently been proposed as a novel candidate gene for epilepsy, with or without developmental delay.
Marlene Rong   +23 more
wiley   +1 more source

Diagnostic imaging and successful outcome of a lateral collateral ligament desmitis of the elbow joint

open access: yesEquine Veterinary Education, EarlyView.
Summary A 13‐year‐old Belgian jumping mare was presented with acute onset of severe left forelimb lameness after a jumping competition. Radiographic evaluation showed the presence of periosteal bone formation on the lateral radial eminence, while ultrasonography revealed an injury of the lateral collateral ligament of the elbow associated with severe ...
E. Porzio   +4 more
wiley   +1 more source

Stable and Highly Steerable Magnetic Nanorobots Demonstrate Therapeutical Functionality in Crowded Biological Media. [PDF]

open access: yesACS Nano
Behera J   +13 more
europepmc   +1 more source

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