Results 1 to 10 of about 32,848 (294)

Simulating drug penetration during hyperthermic intraperitoneal chemotherapy [PDF]

Drug Delivery, 2021
Hyperthermic intraperitoneal chemotherapy (HIPEC) is administered to treat residual microscopic disease after debulking cytoreductive surgery. During HIPEC, a limited number of catheters are used to administer and drain fluid containing chemotherapy (41 ...
Daan R. Löke, Roxan F. C. P. A. Helderman, Nicolaas A. P. Franken, Arlene L. Oei, Pieter J. Tanis, Johannes Crezee, H. Petra Kok   +6 more
doaj   +4 more sources

Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer [PDF]

New England Journal of Medicine, 2018
(Abstracted from N Engl J Med 2018;378:230–240) The majority of patients with ovarian cancer (OC) receive an initial diagnosis of advanced disease that has spread from the ovaries to the peritoneal surface. The most effective treatment for patients with advanced disease is cytoreductive surgery followed by systemic chemotherapy.
W. V. van Driel, S. Koole, K. Sikorska, J. H. Schagen van Leeuwen, H. Schreuder, R. Hermans, I. D. de Hingh, J. van der Velden, H. Arts, L. Massuger, A. Aalbers, V. Verwaal, J. Kieffer, K. K. van de Vijver, H. van Tinteren, N. Aaronson, G. Sonke   +16 more
semanticscholar   +18 more sources

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer with Synchronous Peritoneal Metastases: Multicenter Study of ‘Italian Peritoneal Surface Malignancies Oncoteam—S.I.C.O.’ [PDF]

Annals of Surgical Oncology, 2021
The development of multimodality treatment, including cytoreductive surgery (CRS) with heated intraperitoneal chemotherapy (HIPEC), has led to promising results in selected patients with peritoneal disease of gastric origin.
Luigi Marano, Daniele Marrelli, Paolo Sammartino, Daniele Biacchi, Luigina Graziosi, Elisabetta Marino, Federico Coccolini, Paola Fugazzola, Mario Valle, Orietta Federici, Dario Baratti, Marcello Deraco, Andrea Di Giorgio, Antonio Macrì, Enrico Maria Pasqual, Massimo Framarini, Marco Vaira, Franco Roviello, the Italian Peritoneal Surface Malignancies Oncoteam (S.I.C.O.)   +18 more
openalex   +2 more sources

Intra-Abdominal Desmoplastic Small Round Cell Tumor (DSRCT) and the Role of Hyperthermic Intraperitoneal Chemotherapy (HIPEC): A Review

Current Oncology, 2023
Desmoplastic small round cell tumor is a very rare and highly aggressive soft tissue sarcoma, usually presenting with multiple intra-abdominal tumors in young males. Patients present with advanced disease and the overall survival is dismal.
Sophie J. M. Reijers, Caroline C. H. Siew, Niels F. M. Kok, Charles Honoré, Winan J. van Houdt   +4 more
doaj   +2 more sources

Hyperthermic Intraperitoneal Chemotherapy: A Critical Review [PDF]

Cancers, 2021
Simple Summary Patients with cancer of the digestive system or ovarian cancer are at risk of developing peritoneal metastases (PM). In some patients with PM, surgery followed by intraperitoneal (IP) chemotherapy has emerged as a valid treatment option ...
W. Ceelen, J. Demuytere, I. D. de Hingh
semanticscholar   +6 more sources

Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer [PDF]

Diagnostics, 2020
Hyperthermic intraperitoneal chemotherapy (HIPEC) in conjunction with cytoreductive surgery (CRS) holds promise as an adjunctive treatment strategy in malignancies affecting the peritoneal surface, effectively targeting remaining microscopic residual ...
McKayla J. Riggs, Prakash K. Pandalai, Joseph Kim, Charles S. Dietrich   +3 more
doaj   +3 more sources

Anesthetic implications in hyperthermic intraperitoneal chemotherapy

Journal of Anaesthesiology Clinical Pharmacology, 2019
Patients with peritoneal carcinomatosis were considered incurable with dismal survival rates till hyperthermic intraperitoneal chemotherapy after optimal cytoreductive surgery evolved. Perioperative management for these procedures is complex and involves
Nishkarsh Gupta, Vinod Kumar, Rakesh Garg, Sachidanand Jee Bharti, Seema Mishra, Sushma Bhatnagar   +5 more
doaj   +3 more sources

Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer

Annals of Surgical Oncology, 2023
Hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment modality that aims to target the main site of tumor dissemination in ovarian cancer, the peritoneum, by combining the benefits of intraperitoneal chemotherapy with the synergistic effects of hyperthermia all during a single administration at the time of cytoreductive surgery. High-quality
Julia H. Gelissen, Naomi N. Adjei, B. McNamara, L. Mutlu, J. Harold, M. Clark, G. Altwerger, P. Dottino, Gloria S. Huang, A. Santin, M. Azodi, E. Ratner, P. Schwartz, V. Andikyan   +13 more
semanticscholar   +3 more sources

Hyperthermic intraperitoneal chemotherapy: Ideal and reality

Asian Journal of Surgery
Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) is a new adjuvant therapy for the treatment of abdominal malignant tumors and metastases, which has shown great potential.
Fan-He Dong, Yu-Qiang Shan, Wen-Cheng Kong, Hao-Ran Wei, Lin-Po Zhou, Ye-Bin Yang, Jing Shi, Cheng-Hao Ji, Yi-Jia Zhang   +8 more
doaj   +3 more sources

Glisson’s capsule blistering after hyperthermic intraperitoneal chemotherapy

Annals of Hepatology, 2012
Hypertermic intraperitoneal chemotherapy is a treatment option after cytorreduction of certain types of malignancies with peritoneal spread. Blistering of the Glisson’s capsule has not been previously reported as a consequence of this treatment modality.
Heriberto Medina-Franco, Daniel Zamora-Valdés, Ariadne Sánchez-Ramón, Gabriela Trejo-Gómez   +3 more
doaj   +3 more sources