Results 31 to 40 of about 13,758 (226)

Perception, knowledge and protective practices for surgical staff handling antineoplastic drugs during HIPEC and PIPAC

Pleura and Peritoneum, 2022
Two surgical techniques used for peritoneal metastasis involve a risk of exposure to antineoplastic drugs (ADs): hyperthermic intraperitoneal chemotherapy (HIPEC) and pressurized intraperitoneal aerosol chemotherapy (PIPAC).
Benoist Hubert, Eveno Clarisse, Wilson Sarah, Vigneron Nicolas, Guilloit Jean-Marc, Morello Rémy, Simon Nicolas, Odou Pascal, Saint-Lorant Guillaume   +8 more
doaj   +1 more source

Epididymitis following Cytoreductive Surgery with Intraperitoneal Oxaliplatin Chemotherapy: Two Case Reports

Case Reports in Oncology, 2016
Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy has emerged as an aggressive treatment option with intent to either cure or extend disease-free survival of selected patients with peritoneal carcinomatosis.
Luiza Damian Ribeiro Barbosa, Marcos Belotto, Renata D'Alpino Peixoto   +2 more
doaj   +1 more source

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

, 2020
Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena, Ceelen, Wim, Remaut, Katrien, Van Ramshorst, Gabrielle, Willaert, Wouter   +4 more
core   +1 more source

Targeting the tumor microenvironment in colorectal peritoneal metastases

, 2020
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim, De Wever, Olivier, Heriot, Alexander G., Narasimhan, Vignesh, Ramsay, Robert G.   +4 more
core   +1 more source

Peritoneal carcinomatosis [PDF]

, 2013
Several gastrointestinal and gynecological malignancies have the potential to disseminate and grow in the peritoneal cavity. The occurrence of peritoneal carcinomatosis (PC) has been shown to significantly decrease overall survival in patients with liver
Ansaloni L, BAIOCCHI, Gian Luca, Catena F., Coccolini F, Ghermandi C, GHEZA, Federico, GIULINI, Stefano Maria, Iusco D, Lotti M, Melotti R, Virzì S   +10 more
core   +1 more source

Intraperitoneal chemotherapy for gastric cancer with peritoneal carcinomatosis: is HIPEC the only answer? [PDF]

, 2014
Gastric cancer with peritoneal carcinomatosis is notorious for its dismal prognosis. While the pathophysiology of peritoneal dissemination is still controversial, the rapid downhill course is universal.
Kwong, DLW, Lam, KO, Law, BTT, Law, SYK
core   +1 more source

Adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colon cancer at high risk of peritoneal carcinomatosis; the COLOPEC randomized multicentre trial [PDF]

, 2015
Background: The peritoneum is the second most common site of recurrence in colorectal cancer. Early detection of peritoneal carcinomatosis (PC) by imaging is difficult.
Aalbers, A.G.J. (Arend), Bemelman, W.A. (Willem), Boerma, D. (Djamila), Bremers, A.J.A. (Andreas), Burger, J.W.A. (Jacobus), Buskens, C.J. (Christianne), Dijkgraaf, M.G.W. (Marcel), Evers, P. (Pauline), Grevenstein, H.M.U. (Helma) van, Hemmer, P.H.J. (Patrick H.J.), Hingh, I.H.J.T. (Ignace) de, Klaver, C.E.L. (Charlotte), Lammers, L.A. (Laureen), Leeuwen, B.L. (B.) van, Meijerink, W.J.H.J. (Jeroen), Musters, G.D. (Gijsbert), Nienhuijs, S.W. (Simon), Pon, J. (Jolien), Punt, C.J.A. (Cornelis), Radema, S.A. (Sandra A.), Ramshorst, B. (Bert) van, Snaebjornsson, P., Tanis, P.J. (Pieter), te Velde, E.A. (Elisabeth A.), Tuynman, J.B., van der Bilt, J.D.W. (Jarmila D.W.), van Ginkel, R.J. (Robert J.), Verwaal, V.J. (Vic J.), Wiezer, M.J. (Marinus), Wilt, J.H.W. (Johannes) de   +29 more
core   +4 more sources

Perioperative anaesthetic management in cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC): a retrospective analysis in a single tertiary care cancer centre

Pleura and Peritoneum, 2022
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with increased morbidity and mortality. We retrospectively analysed the perioperative anesthetic management in patients undergoing HIPEC surgery.
Gupta Raghav, Gupta Nishkarsh, Sirohiya Prashant, Pandit Anuja, Ratre Brajesh Kumar, Vig Saurabh, Bhan Swati, Singh Ram, Kumar Balbir, Bhopale Shweta, Mishra Seema, Garg Rakesh, Bharati Sachidanand Jee, Kumar Vinod, Deo Suryanarayana, Bhatnagar Sushma   +15 more
doaj   +1 more source

A Dose-Finding Trial for Hyperthermic Intraperitoneal Cisplatin in Gynecological Cancer Patients Receiving Hyperthermic Intraperitoneal Chemotherapy

Frontiers in Oncology, 2021
Background: To identify the maximum tolerated dose (MTD) of hyperthermic intraperitoneal cisplatin at 43°C among gynecological cancer patients.Methods: In this Phase I dose-finding trial, Bayesian optimal interval (BOIN) design was used.
Chui-ying Chan, Hui Li, Miao-fang Wu, Chang-hao Liu, Huai-wu Lu, Zhong-qiu Lin, Jing Li   +6 more
doaj   +1 more source

Albumin-based cancer therapeutics for intraperitoneal drug delivery : a review [PDF]

, 2020
Albumin is a remarkable carrier protein with multiple cellular receptor and ligand binding sites, which are able to bind and transport numerous endogenous and exogenous compounds.
Al Rawahi T, Carlier C, Daugirdas JT, Dedrick RL, Fan R, Flessner MF, Goodman MD, Hartung G, Kragh-Hansen U., Lotze MT, Maltas E, Oseledchyk A, Sjobring U, Sun C, Zhao D   +14 more
core   +2 more sources