Results 51 to 60 of about 8,896 (223)

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: patient selection and special considerations [PDF]

, 2019
Laura M Enomoto, Perry Shen, Edward A Levine, Konstantinos I VotanopoulosWake Forest Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USAAbstract: Malignant peritoneal mesothelioma (MPM) is a rare, aggressive malignancy that ...
Enomoto LM, Shen P, Levine EA, Votanopoulos KI   +3 more
core  

Hyperthermic Intraperitoneal Chemotherapy in Treating Women With Pelvic Cancer: Cohort Study [PDF]

, 2022
Ovarian cancer is the most aggressive gynecologic cancer and is associated with lower survivor compared to other gynecologic malignancies. Hyperthermic Intraperitoneal Chemotherapy (HIPEC) has been offered as an added therapy which can in selected ...
Sivvan Chinniah, Matthew Robertson, Tri Dinh, Hannah Palin, Sherif El-Nashar   +4 more
core   +1 more source

Potential survival benefits from optimized chemotherapy implementation in advanced ovarian cancer: Projections from a microsimulation model.

PLoS ONE, 2019
BackgroundOvarian cancer is often diagnosed in advanced stages, when survival is poor. Treatment advances have been made, but are inconsistently implemented.
Anna P Lietz, Davis T Weaver, Alexander Melamed, Jose Alejandro Rauh-Hain, Jason D Wright, Alexi A Wright, Amy B Knudsen, Pari V Pandharipande   +7 more
doaj   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

“Adjuvant” Hyperthermic Intraperitoneal Chemotherapy: A Call to Action [PDF]

Annals of Surgical Oncology, 2016
The highly experienced team of Baratti et al. used hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colorectal cancer at high risk for peritoneal metastases. The literature reports an overall median survival of only 1–2 years for this patient population, even in the setting of contemporary systemic chemotherapy.
John C, McAuliffe, Garrett M, Nash
openaire   +2 more sources

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for appendiceal goblet cell carcinomas with peritoneal carcinomatosis: results from a single specialized center [PDF]

, 2017
Hsin-Hsien Yu,1,2 Yutaka Yonemura,3–5 Mao-Chih Hsieh,1,2 Akiyoshi Mizumoto,4 Satoshi Wakama,3 Chang-Yun Lu1,2 1Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 2Division of General Surgery ...
Wakama S, Mizumoto A, Hsieh MC, Lu CY, Yonemura Y, Yu HH   +5 more
core  

Intraperitoneal chemotherapy for gastric cancer with peritoneal carcinomatosis: is HIPEC the only answer? [PDF]

, 2014
Gastric cancer with peritoneal carcinomatosis is notorious for its dismal prognosis. While the pathophysiology of peritoneal dissemination is still controversial, the rapid downhill course is universal.
Lam, KO, Law, SYK, Kwong, DLW, Law, BTT
core   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Hyperthermic intraperitoneal chemotherapy: Rationale and technique

World Journal of Gastrointestinal Oncology, 2010
The combination of complete cytoreductive surgery and perioperative intraperitoneal chemotherapy provides the only chance for long-term survival for selected patients diagnosed with a variety of peritoneal neoplasms, either primary or secondary to digestive or gynecologic malignancy.
Santiago, González-Moreno, Luis A, González-Bayón, Gloria, Ortega-Pérez   +2 more
openaire   +2 more sources