Results 51 to 60 of about 491,575 (216)

Preoperative Frailty as a Predictor of Quality of Life Outcomes Following Cytoreductive Surgery

World Journal of Surgery, EarlyView.
Frailty has emerged as a critical determinant of postoperative risk in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS + HIPEC). However, its impact on postoperative quality of life (QoL) remains underexplored.
Zirong Bai, Laura Barker, Rihan Shahab, Cherry Koh, Michael Solomon, Kate Alexander, Sascha Karunaratne, Nabila Ansari, Leani Souza Maximo Pereira, Ana Paula Drummond Lage, Daniel Steffens   +10 more
wiley   +1 more source

Prophylactic hyperthermic intraperitoneal chemotherapy can be considered in the management of advanced gastric cancer

, 2016
We read with interest the article by Dehal, Smith and Nash (1), intitled “Cytoreductive surgery and intraperitoneal chemotherapy: an evidence-based review—past, present and future” and, also congratulating them for the comprehensive review performed, we ...
Saladino, Edoardo, MACRI', Antonio
core   +1 more source

Gastrointestinal Stimulation as a Prevention of Postoperative Ileus Following Extensive Surgery (STIMULATE)‐ a Pilot Feasibility Study

World Journal of Surgery, EarlyView.
This randomized feasibility study evaluated the safety and feasibility of gastric electrical stimulation for the prevention of postoperative ileus after extensive abdominal surgery. The intervention was safe and well tolerated. These findings support further clinical investigation of gastrointestinal stimulation as a potential strategy to reduce ...
Anne K. Martensen, Thomas Nielsen, Anne Bodilsen, Mette M. Sørensen, Lene H. Iversen, Jonas A. Funder   +5 more
wiley   +1 more source

Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment

The FEBS Journal, EarlyView.
Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro, Aurore Dougé, Klara Krpina, Lea‐Marie Schmitz, Christopher Forcados, Fatemeh Kaveh, Andrea Estrella Arias‐Díaz, Pascal Gelebart, Emmet McCormack, Renata Stripecke, Miguel Abal, Ben Davidson, Else Marit Inderberg, Sébastien Wälchli   +13 more
wiley   +1 more source

“Adjuvant” Hyperthermic Intraperitoneal Chemotherapy: A Call to Action [PDF]

Annals of Surgical Oncology, 2016
The highly experienced team of Baratti et al. used hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colorectal cancer at high risk for peritoneal metastases. The literature reports an overall median survival of only 1–2 years for this patient population, even in the setting of contemporary systemic chemotherapy.
John C, McAuliffe, Garrett M, Nash
openaire   +2 more sources

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

Photochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore, Brian Schnoor, Kathryn L. McNaughton, Idrisa Rahman, Benjamin D. Powers, Dana M. Roque, Huang‐Chiao Huang   +6 more
wiley   +1 more source

A rare case of recurrent epidermoid anal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy—case report

World Journal of Surgical Oncology, 2020
Background Anal cancer is a rare cancer with chemoradiation being the mainstay of treatment for locoregional presentation. In North America, the most common subtype is anal squamous cell carcinoma (epidermoid).
Vera Pravong, Alexandre Brind’Amour, Lucas Sidéris, Pierre Dubé, Jean-François Tremblay   +4 more
doaj   +1 more source

Advances in Treatment Models of Advanced Gastric Cancer

Technology in Cancer Research & Treatment, 2022
The prognosis of advanced gastric cancer (AGC) is extremely poor, and the therapeutic effect of traditional palliative chemotherapy is far from satisfactory.
Tao Li, Yufang He, Qinglei Zhong, Jiang Yu, Xinhua Chen   +4 more
doaj   +1 more source

Epidemiological and Prognostic Differences in Malignant Mesothelioma Between Eastern China and SEER Database

Cancer Science, Volume 117, Issue 11, Page 3146-3159, November 2026.
For long years, patients and clinicians in Eastern China used Western data as information foundation for management and treatment of malignant mesothelioma, due to its rarity and lack of deep investigation. This study updated the epidemiological data of malignant mesothelioma in Eastern China, and revealed better survival outcomes compared to Western ...
Ningning Li, Ruting Wang, Wenya Zhang, Zulei Shao, Hongyu Lin, Guanai Bao, Weimin Mao, Zhongjian Chen   +7 more
wiley   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, Volume 73, Issue S4, October 2026.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source