Results 41 to 50 of about 8,896 (223)

A Dose-Finding Trial for Hyperthermic Intraperitoneal Cisplatin in Gynecological Cancer Patients Receiving Hyperthermic Intraperitoneal Chemotherapy

Frontiers in Oncology, 2021
Background: To identify the maximum tolerated dose (MTD) of hyperthermic intraperitoneal cisplatin at 43°C among gynecological cancer patients.Methods: In this Phase I dose-finding trial, Bayesian optimal interval (BOIN) design was used.
Chui-ying Chan, Hui Li, Miao-fang Wu, Chang-hao Liu, Huai-wu Lu, Zhong-qiu Lin, Jing Li   +6 more
doaj   +1 more source

Perioperative anaesthetic management in cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC): a retrospective analysis in a single tertiary care cancer centre

Pleura and Peritoneum, 2022
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with increased morbidity and mortality. We retrospectively analysed the perioperative anesthetic management in patients undergoing HIPEC surgery.
Gupta Raghav, Gupta Nishkarsh, Sirohiya Prashant, Pandit Anuja, Ratre Brajesh Kumar, Vig Saurabh, Bhan Swati, Singh Ram, Kumar Balbir, Bhopale Shweta, Mishra Seema, Garg Rakesh, Bharati Sachidanand Jee, Kumar Vinod, Deo Suryanarayana, Bhatnagar Sushma   +15 more
doaj   +1 more source

Technology development of hyperthermic pressurized intraperitoneal aerosol chemotherapy (hPIPAC) [PDF]

, 2021
Background!#!Optimized drug delivery systems are needed for intraperitoneal chemotherapy. The aim of this study was to develop a technology for applying pressurized intraperitoneal aerosol chemotherapy (PIPAC) under hyperthermic conditions (hPIPAC ...
Reymond, Marc, Königsrainer, A., Bachmann, C., Weinreich, F. J., Nadiradze, G., Sautkin, I., Archid, R.   +6 more
core   +1 more source

Hyperthermic intraperitoneal chemotherapy in colorectal cancer

BJS Open
Abstract Background This study evaluated the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) in colorectal cancer with peritoneal metastases (pmCRC) in a large international data set of patients.
Rau, Beate, Gül-Klein, Safak
openaire   +5 more sources

Simulating drug penetration during hyperthermic intraperitoneal chemotherapy

Drug Delivery, 2021
Hyperthermic intraperitoneal chemotherapy (HIPEC) is administered to treat residual microscopic disease after debulking cytoreductive surgery. During HIPEC, a limited number of catheters are used to administer and drain fluid containing chemotherapy (41 ...
Daan R. Löke, Roxan F. C. P. A. Helderman, Nicolaas A. P. Franken, Arlene L. Oei, Pieter J. Tanis, Johannes Crezee, H. Petra Kok   +6 more
doaj   +1 more source

The Role of Hyperthermic Intraperitoneal Chemotherapy in Gastric Cancer [PDF]

Indian Journal of Surgical Oncology, 2016
Peritoneal metastasis, either synchronous or metachronous, is commonly seen in gastric cancer. It is associated with a poor prognosis, with a median survival of less than one year. The outcomes are not significantly improved by the use of systemic chemotherapy. We review the relevant literature on the role of HIPEC in gastric cancer.
Ramakrishnan Ayloor, Seshadri, Olivier, Glehen   +1 more
openaire   +2 more sources

Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy for Malign Peritoneal Mesothelioma: Clinical Aspects and Therapeutic Perspectives [PDF]

, 2021
Malignant mesotheliomas develop commonly in the pleural cavity and second mesotheliomas arise in the peritoneal cavity (20-30%). Most frequent symptoms/signs are ascites (77%) and abdominal pain (f69%).
Miftari, Almir, Firat, Ozgur, Sezer, Taylan Ozgur, Ersin, Sinan   +3 more
core   +1 more source

Feasibility of hyperthermic pressurized intraperitoneal aerosol chemotherapy in a porcine model [PDF]

, 2016
BACKGROUND: Peritoneal carcinomatosis is an unmet therapeutic need. Several types of intraperitoneal chemotherapy have been introduced. However, hyperthermic intraperitoneal chemotherapy has limited drug distribution and poor peritoneal penetration ...
Park, YS, Kim, HH, Jung, DH, Son, SY, Shin, DJ, Oo, AM, Ahn, SH, Park, DJ   +7 more
core   +1 more source

Indication of Hyperthermic Intraperitoneal Chemotherapy in Gastric Cancer (Gastripec, Gastrichip) [PDF]

, 2022
Background: Gastric cancer (GC) is associated with a poor prognosis mostly due to peritoneal metastasis, which will develop in time during the patient's disease history.
Thuss-Patience, Peter, Bonnot, Pierre Emmanuel, Gronau, Felix, Alberto Vilchez, Miguel Enrique, Glehen, Olivier, Rau, Beate, Feldbrügge, Linda   +6 more
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source