Results 71 to 80 of about 15,790 (257)

Intraperitoneal aerosolization of albumin-stabilized paclitaxel nanoparticles (Abraxane™) for peritoneal carcinomatosis : a phase I first-in-human study [PDF]

, 2018
Background: Nanoparticles hold considerable promise for aerosol-based intraperitoneal delivery in patients with carcinomatosis. Recently, results from preclinical and early clinical trials suggested that albumin-bound paclitaxel (ABP, Abraxane (TM)) may ...
Ceelen, Wim, Cosyns, Sarah, Graversen, Martin, Hubner, Martin, Pocard, Marc, Reymond, Marc, Vaira, Marco, Van de Sande, Leen, Willaert, Wouter   +8 more
core   +3 more sources

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, Volume 5, Issue 6, June 2025.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

Clinical outcomes of complete cytoreduction with concurrent liver resection followed by hyperthermic intraperitoneal chemotherapy for synchronous peritoneal and liver metastatic colorectal cancer

World Journal of Surgical Oncology, 2019
Background This study aimed to evaluate the clinical outcomes of concurrent liver resection with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in colorectal cancer patients with synchronous liver and peritoneal metastases.
Youngbae Jeon, Eun Jung Park, Jin Hong Lim, Seung Hyuk Baik   +3 more
doaj   +1 more source

New National Network of Experts (Japan Pelvic Exenteration Network: J‐PEN) Formed in a Bid to Improve Outcomes of Pelvic Exenteration in Japan

Annals of Gastroenterological Surgery, EarlyView.
Hideaki Yano, Alex Mirnezami, Masataka Ikeda, Kay Uehara, Shuichiro Matoba, Yuichiro Tsukada, Toshiki Mukai, Kei Kimura, Yudai Fukui, Naoyuki Toyota   +9 more
wiley   +1 more source

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

Advanced Healthcare Materials, Volume 14, Issue 14, May 28, 2025.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang, Mara Artibani, Yongcheng Jin, Aneesh Aggarwal, Yujia Zhang, Sandra Muñoz‐Galvan, Ellina Mikhailova, Lena Rai, Nobina Mukherjee, Ravinash Krishna Kumar, Ashwag Albukhari, Shaohua Ma, Linna Zhou, Ahmed Ashour Ahmed, Hagan Bayley   +14 more
wiley   +1 more source

Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap

Journal of Contemporary Brachytherapy, 2016
Purpose : To report peri-operative fractionated high-dose-rate (HDR) brachytherapy with a 3D customized Freiburg flap applicator to treat locally recurrent Wilms’ tumor, followed by immediate hyperthermic intraperitoneal chemotherapy for a 16-year-old ...
Emily Flower, Kathy Ngoc Tran, Salman Zanjani, Wayne Smith, Jonathan Karpelowsky, Katie Summerhayes, Edgar Estoesta, Jennifer Chard   +7 more
doaj   +1 more source

Study on the thermal stability of nab-paclitaxel during hyperthermic intraperitoneal chemotherapy

BMC Pharmacology and Toxicology, 2023
Background Albumin-bound paclitaxel (nab-paclitaxel), as a special targeted preparation of paclitaxel, has the advantages of good curative effect and less side effects in anti-tumor therapy. The existence of the plasma-peritoneal barrier and insufficient
Jingjing Zhang, Luya Li, Jintuo Yin, Xidong Zhang, Ying Zheng, Rui Feng   +5 more
doaj   +1 more source

Intraperitoneal photodynamic therapy causes a capillary-leak syndrome. [PDF]

, 2003
BackgroundIn patients undergoing intraperitoneal (IP) photodynamic therapy (PDT), the combination of aggressive surgical debulking and light therapy causes an apparent systemic capillary-leak syndrome that necessitates significant intensive care unit ...
Canter, Robert J, Fraker, Douglas L, Glatstein, Eli J, Hahn, Stephen M, Kesmodel, Susan B, Metz, James M, Mick, Rosemarie, Raz, Dan J, Spitz, Francis R   +8 more
core   +2 more sources

Tonic-Clonic Seizure following Cytoreductive Surgery with Intraperitoneal Oxaliplatin: A Case Report and Review of the Literature

Case Reports in Oncology, 2016
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal (IP) chemotherapy (HIPEC) is believed to improve outcomes in well-selected patients with peritoneal carcinomatosis.
Jessica Sayuri Tsukamoto, Marcos Belotto de Oliveira, Renata D'Alpino Peixoto   +2 more
doaj   +1 more source

Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in small bowel adenocarcinoma with peritoneal metastasis: a systematic review

Pleura and Peritoneum, 2022
Small bowel adenocarcinoma (SBA) with peritoneal metastasis (PM) is rare and despite treatment with systemic chemotherapy, the prognosis is poor. However, there is emerging evidence that cytoreductive surgery (CRS) with hyperthermic intraperitoneal ...
Chen Vicky, Jones Morgan, Cohen Lauren, Yang Wilson, Bedi Jasman, Mohan Helen M., Apte Sameer S., Larach José Tomas, Flood Michael, Heriot Alexander, Kong Joseph, Warrier Satish   +11 more
doaj   +1 more source