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The Role of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Ovarian Cancer
AbstractOverall outcomes for women with epithelial ovarian cancer (EOC) remain relatively poor, and superior methods of treatment are needed. EOC is a peritoneal surface malignancy that is relatively sensitive to chemotherapy agents, making it a good target for i.p. chemotherapy.
C William Helm
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Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Methodology, Drugs and Bidirectional Chemotherapy [PDF]
Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) combined have been recognized as standard of care for treatment of a subset of patients with peritoneal carcinomatosis (PC). The aim of CRS is to eliminate all macroscopic disease through a series of visceral resections followed by targeting any residual microscopic ...
Sarah Valle, W Liauw
exaly +3 more sources
Hyperthermic intraperitoneal chemotherapy (HIPEC) in ovarian cancer
Ovarian cancer remains the fourth leading cause of cancer death in women in France. It is all too often diagnosed at an advanced stage with peritoneal carcinomatosis (PC), but remains confined to the peritoneal cavity throughout much of its natural history.
Gautier Chene +2 more
exaly +3 more sources
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Hyperthermic intraperitoneal chemotherapy (HIPEC) for gynecological cancer
Journal of Obstetrics and Gynaecology Research, 2020AbstractAimHyperthermic intraperitoneal chemotherapy (HIPEC) is a method of administering anticancer agents directly while heating the abdominal cavity. The aim of this review is to know the current position of HIPEC in ovarian cancer and uterine sarcoma and its future prospects.MethodsThis article reviews the current literature and evidence for the ...
Hideaki, Tsuyoshi +3 more
openaire +2 more sources
Anesthesia for Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
2021HIPEC is a highly concentrated, heated chemotherapy treatment that is delivered directly into the abdominal cavity after cytoreductive surgery (CRS). Anesthetic management for Cytoreductive surgery (CRS) with HIPEC (hyperthermic intraperitoneal chemotherapy) involves multiple challenges including the patient’s preoperative health status, disease load ...
Eilish M. Galvin +2 more
openaire +1 more source
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Techniques
2015Peritoneal carcinomatosis has long been considered a terminal condition and constitutes a difficult therapeutic challenge given the dismal prognosis associated with this entity and the debilitating effect it exerts on affected patients. Over the past decade, novel therapeutic approaches to peritoneal surface malignancies have emerged.
Salvatore Virzì +3 more
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Toxicities and doses of chemotherapy drugs in hyperthermic intraperitoneal chemotherapy (HIPEC).
Journal of Clinical Oncology, 2015e13524 Background: Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) to treat mucinous intra-abdominal tumors began in 1980.1 More recently, the combination of complete cytoreductive surgery and ...
Samuel Danial Pandiyan +2 more
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Acta Chirurgica Belgica, 2004
Up to now, the prognosis of peritoneal carcinomatosis from GI tract cancers remains very poor. Intraperitoneal hyperthermic chemotherapy has been proposed in the prevention or treatment of peritoneal carcinomatosis. The rationale for this locoregional approach comes from a better knowledge of the physiopathology of the disease.
Detroz, Bernard +5 more
openaire +2 more sources
Up to now, the prognosis of peritoneal carcinomatosis from GI tract cancers remains very poor. Intraperitoneal hyperthermic chemotherapy has been proposed in the prevention or treatment of peritoneal carcinomatosis. The rationale for this locoregional approach comes from a better knowledge of the physiopathology of the disease.
Detroz, Bernard +5 more
openaire +2 more sources
Annals of Surgical Oncology, 2018
The introduction of cytoreductive surgery (CRS) in combination with hyperthermic intraperitoneal chemotherapy (HIPEC) improved the prognosis of selected patients with peritoneal mesothelioma (PM).The objective of our study was to evaluate whether different HIPEC agents were associated with different outcomes in patients with PM.From the RENAPE database,
Diane Goere +2 more
exaly +5 more sources
The introduction of cytoreductive surgery (CRS) in combination with hyperthermic intraperitoneal chemotherapy (HIPEC) improved the prognosis of selected patients with peritoneal mesothelioma (PM).The objective of our study was to evaluate whether different HIPEC agents were associated with different outcomes in patients with PM.From the RENAPE database,
Diane Goere +2 more
exaly +5 more sources
The role of hyperthermic intraperitoneal chemotherapy (HIPEC) in ovarian cancer
Gynecologic OncologyHyperthermic intraperitoneal chemotherapy (HIPEC) is increasingly recognized as an effective addition to cytoreductive surgery in advanced ovarian cancer, particularly in patients who respond to platinum-based chemotherapy.A systematic review of phase III randomized controlled trials testing the role of HIPEC in ovarian cancer was performed, according ...
Bogani G. +10 more
openaire +4 more sources

