Opening closed inward rectifier potassium channel doors
Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger +3 more
wiley +1 more source
Abstract Background Inhaled saline may improve mucus transport in respiratory diseases, for example, cystic fibrosis. This randomised, placebo‐controlled, crossover study examined the effect of inhaled dry NaCl on mucociliary clearance in patients with chronic obstructive pulmonary disease (COPD). Methods Twenty‐five patients with GOLD stage I‐III COPD
Rie Skovly Thomsen +7 more
wiley +1 more source
Efficacy of prolotherapy in temporomandibular joint disorders with hypertonic dextrose and Polydeoxyribonucleotide (PDRN). [PDF]
Choi JW, Kim YK, Yun PY, Ku JK.
europepmc +1 more source
Chromaffin Versus Platelet Granules: What We Have Learned From Chromaffin Cells for Human Studies
Chromaffin cells and platelets both utilize exocytosis to release biogenic amines stored within large dense‐core vesicles—specifically chromaffin granules (epinephrine) and δ‐granules (serotonin). While the chromaffin cell is the foundational model for studying the secretory pathway, platelets offer a highly accessible human cell source for clinical ...
Ricardo Borges
wiley +1 more source
The effect of experimentally induced acute pain on lumbar movement control: a single blinded three-arm cross-over randomized control trial. [PDF]
Schüßler B +6 more
europepmc +1 more source
Sodium bicarbonate for "metabolic acidosis": an illustration of the Goodhart's law. [PDF]
Diop S +3 more
europepmc +1 more source
Drinking microstructure analysis of direct controls of water intake in male and female rats. [PDF]
Sortman BW +6 more
europepmc +1 more source
Short-Term Sleep Disruption Does Not Modify Responses to Experimentally Induced Knee Pain in Healthy Individuals. [PDF]
Hertel E +6 more
europepmc +1 more source
New aspects of the Slug Mucosal Irritation assay: predicting nasal stinging, itching and burning sensations [PDF]
Adam +52 more
core +1 more source

