Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis. [PDF]
, 2017 Glucocorticoids promote lipolysis in white adipose tissue (WAT) to adapt to energy demands under stress, whereas superfluous lipolysis causes metabolic disorders, including dyslipidemia and hepatic steatosis. Glucocorticoid-induced lipolysis requires the
Broughton, Augusta E +6 more
core +1 more source
Is hypertriglyceridemia atherogenic? [PDF]
La Presse Médicale, 2018 ASCVD reduction is based on LDL reduction, especially by statins. Highly elevated TG could be harmful, especially because of the risk of pancreatitis. Elevation of TG is mainly due to metabolic disorders and diabetes, alcohol intake and overweight. Genetic factors have been clearly identified in the most severe cases.
Florence Leclercq +8 more
openaire +3 more sources
Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. [PDF]
, 2018 Activation of liver X receptors (LXRs) with synthetic agonists promotes reverse cholesterol transport and protects against atherosclerosis in mouse models.
Bahadorani, John +16 more
core +1 more source
Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection [PDF]
, 2016 We report experimental evidence confirming renal histopathology, proinflammatory mediators, and oxidative metabolism induced by cola drinking. Male Wistar rats drank ad libitum regular cola (C, = 12) or tap water (W, = 12). Measures.
Ambrosio, Giuseppe +7 more
core +1 more source
Pregnancies Complicated by Familial Hypertriglyceridemia: A Case Report
American Journal of Perinatology Reports, 2018 Background Although rare, familial hypertriglyceridemia can cause acute and life-threatening complications in pregnancy. Cases The first patient's pregnancy was complicated by multiple admissions for pancreatitis due to hypertriglyceridemia ...
Suzanne Cao +3 more
doaj +1 more source
Clinical Conditions and History of Illness Among Terminal Chronic Kidney Disease Patients [PDF]
, 2019 End-stage renal disease (ESRD) is one of the public health problems in Indonesia. This study aimed to determine the clinical condition of premorbid and the incidence of ESRD. The study design is a case-control.
Adiningrat, A. (Arya) +2 more
core +4 more sources
Apolipoprotein A5 and Hypertriglyceridemia [PDF]
Clinical Chemistry, 2005 Hypertriglyceridemia is associated with increased risk of coronary heart disease (CHD) (1)(2)(3)(4)(5), and it is an integral component of the overlapping syndromes of familial combined hyperlipidemia, insulin resistance syndrome, atherogenic lipoprotein profile, and hyperapobetalipoproteinemia (6).
Charlton-Menys, Valentine +1 more
openaire +3 more sources
Frontiers in Cardiovascular Medicine, 2021 Objective: The objective of the study was to investigate the relationship of amino acid metabolism with hypertriglyceridemia in diabetic patients under statins free of prior cardiovascular diseases.Methods: Two independent cross-sectional hospital based ...
Shuang Wang +13 more
doaj +1 more source
Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. [PDF]
, 2018 Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for hematopoietic stem progenitor cell (HSPC) maintenance.
Han, Tianxu +10 more
core +2 more sources
Hypertriglyceridemia in Antiretroviral Therapy [PDF]
Journal of the International AIDS Society, 2005 Elevated serum triglycerides, total cholesterol, very low-density lipoprotein (VLDL) cholesterol, and low-density lipoprotein (LDL) cholesterol have been reported in the literature from areas where experience with antiretroviral drugs has amassed. Up until recently the use of antiretroviral drugs in Nigeria on a wide scale was a rarity owing largely to
Emmanuel Pandy Kubeyinje +1 more
openaire +4 more sources