Results 41 to 50 of about 98,812 (291)

Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis. [PDF]

, 2017
Glucocorticoids promote lipolysis in white adipose tissue (WAT) to adapt to energy demands under stress, whereas superfluous lipolysis causes metabolic disorders, including dyslipidemia and hepatic steatosis. Glucocorticoid-induced lipolysis requires the
Broughton, Augusta E, Chen, Tzu-Chieh, Kuo, Taiyi, Lee, Rebecca A, Nguyen, Nguyen Huynh Thao, Wang, Jen-Chywan, Zhang, Danyun   +6 more
core   +1 more source

Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]

, 1999
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C, Chajek-Shaul T, Engelmann H, Ettinger WH, Ettinger WH, Ettinger WH, Feingold KR, Feingold KR, Flegel WA, Gouni I, Graham A, Greenberg AS, Grove RI, Grunfeld C, Hubsch AP, Ishibashi S, Kipp HA, Moran CS, Netea MG, Pacelli F, Pak YK, Read TE, Semb H, Stopeck AT, Van Gameren MM, Weinstock C, Wilson DE, Yokoyama K   +27 more
core   +1 more source

Familial Chylomicronemia Syndrome-Induced Acute Necrotizing Pancreatitis during Pregnancy

Revista Brasileira de Ginecologia e Obstetrícia, 2021
Acute pancreatitis is a rare condition in pregnancy, associated with a high mortality rate. Hypertriglyceridemia represents its second most common cause.We present the case of a 38-year-old woman in the 24th week of gestation with a history of ...
Julia Cristina Coronado Arroyo, Marcio José Concepción Zavaleta, Eilhart Jorge García Villasante, Mikaela Kcomt Lam, Luis Alberto Concepción Urteaga, Francisca Elena Zavaleta Gutiérrez   +5 more
doaj   +1 more source

Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. [PDF]

, 2018
Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for hematopoietic stem progenitor cell (HSPC) maintenance.
Han, Tianxu, Kim, Jungsu, Klemke, Richard L, Liu, Chao, Miller, Yury I, Rana, Tariq M, Remaley, Alan T, Stachura, David L, Traver, David, Vaisman, Boris L, Wang, Huawei   +10 more
core   +2 more sources

Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection [PDF]

, 2016
We report experimental evidence confirming renal histopathology, proinflammatory mediators, and oxidative metabolism induced by cola drinking. Male Wistar rats drank ad libitum regular cola (C, = 12) or tap water (W, = 12). Measures.
Ambrosio, Giuseppe, Azzato, Francisco, Cao, Gabriel Fernando, Gómez Llambí de Oromí, Hernán Jorge, Milei, Jose, Muller, Maria Angelica, Otero-Losada, Matilde Estela, Ottaviano, Graciela Mabel   +7 more
core   +1 more source

Phase 1 study of sirolimus in combination with oral cyclophosphamide and topotecan in children and young adults with relapsed and refractory solid tumors. [PDF]

, 2016
PurposeTo determine the maximum tolerated dose (MTD), toxicities, and pharmacodynamics effects of sirolimus combined with oral metronomic topotecan and cyclophosphamide in a pediatric population.Materials and methodsPatients who were 1 to 30 years of age
Allen, Shelly, DuBois, Steven G, Gustafson, W Clay, Hollinger, Fabienne, Karski, Erin E, Long-Boyle, Janel R, Matthay, Katherine K, Nasholm, Nicole M, Shiboski, Stephen, Vo, Kieuhoa T   +9 more
core   +1 more source

Associations of Hypertriglyceridemia Onset Age With Cardiovascular Disease and All‐Cause Mortality in Adults: A Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Limited studies have involved new‐onset hypertriglyceridemia, and this study was to evaluate the associations of hypertriglyceridemia onset age with cardiovascular diseases (CVD) and all‐cause mortality.
Hui Zhou, Xiong Ding, Qing Yang, Shuohua Chen, Yun Li, Xin Zhou, Shouling Wu   +6 more
doaj   +1 more source

Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia

Pediatric Blood & Cancer, 2020
Glucocorticoids and asparaginase, used to treat acute lymphoblastic leukemia (ALL), can cause hypertriglyceridemia. We compared triglyceride levels, risk factors, and associated toxicities in two ALL trials at St.
Emily R. Finch, Colton A. Smith, Wenjian Yang, Yiwei Liu, Nancy M. Kornegay, J. Panetta, K. Crews, A. Molinelli, Cheng Cheng, Deqing Pei, L. Ramsey, Seth E. Karol, H. Inaba, J. Sandlund, M. Metzger, W. Evans, S. Jeha, C. Pui, M. Relling   +18 more
semanticscholar   +1 more source

Clinical Conditions and History of Illness Among Terminal Chronic Kidney Disease Patients [PDF]

, 2019
End-stage renal disease (ESRD) is one of the public health problems in Indonesia. This study aimed to determine the clinical condition of premorbid and the incidence of ESRD. The study design is a case-control.
Adiningrat, A. (Arya), Akrom, A. (Akrom), Hidayati, T. (Titiek)   +2 more
core   +4 more sources

Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia

Circulation, 2019
Supplemental Digital Content is available in the text.
Z. Ahmad, P. Banerjee, S. Hamon, Kuo-Chen Chan, Aurelie Bouzelmat, W. Sasiela, R. Pordy, S. Mellis, H. Dansky, D. Gipe, Richard L. Dunbar   +10 more
semanticscholar   +1 more source