Results 141 to 150 of about 127,568 (322)

Large Language Models in Cardiovascular Imaging: Current Applications and Future Prospects

Med Research, EarlyView.
Weifeng Yuan, Rong Xu, Shengkun Peng, Yingkun Guo   +3 more
wiley   +1 more source

FAM20A Deficiency Drives Transcriptomic Dysregulation and Functional Impairment in Gingival Fibroblasts

Cell Proliferation, EarlyView.
FAM20A variants cause AI1G, marked by enamel defects, gingival overgrowth and ectopic calcifications. RNA sequencing of patient‐derived gingival fibroblasts showed dysregulated genes in adhesion, proliferation and signalling pathways. Functional assays revealed increased cell proliferation, impaired ECM interactions and osteogenesis, suggesting FAM20A ...
Kanokwan Sriwattanapong, Sermporn Thaweesapphithak, Chompak Khamwachirapitak, Pannagorn Sae‐ear, Sasiprapa Prommanee, Noppadol Sa‐Ard‐Iam, Suphalak Phothichailert, Han Sung Jung, Vorasuk Shotelersuk, Thantrira Porntaveetus   +9 more
wiley   +1 more source

Natural products targeting regulated cell deaths for adriamycin-induced cardiotoxicity

Cell Death Discovery
Adriamycin (ADR), as an anti-cancer drug in routine clinical application, is utilized to treat various cancers such as ovarian cancer, hematological malignant tumor, and endometrial carcinoma.
Zheng Wang, Yanli Zhu, Yu Yao, Wenyu Zhang, Bo Wang, Jing Wang, Yang Yang, Liwen Liu   +7 more
doaj   +1 more source

Penetrance of pathogenic epilepsy variants is low and shaped by common genetic background

Epilepsia, EarlyView.
Abstract Objective The identification of pathogenic variants in developmental epileptic encephalopathy (DEE) genes can be vital for counseling and individualized treatment. Penetrance is usually considered to be high or full, although this has never been studied in population cohorts.
Remi Stevelink, M. Martijn Piet, Yorgos Bos, Ruben van ’t Slot, Kees P. J. Braun, Bobby P. C. Koeleman   +5 more
wiley   +1 more source

Impact of atrial fibrillation on the clinical course of apical hypertrophic cardiomyopathy

, 2017
Sang‐Eun Lee, Jin‐Kyu Park, Jae‐Sun Uhm, Jong‐Youn Kim, Hui‐Nam Pak, Moon‐Hyoung Lee, Boyoung Joung   +6 more
openalex   +2 more sources

The First Report of Cod Gill Poxvirus in Gills of Atlantic Cod (Gadus morhua L.) Suffering From Cardiorespiratory Disease

Journal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT Atlantic cod farming experiences renewed growth in Norway, and increased awareness is essential to address emerging diseases in this species. There are few reports on gill diseases in cod, and to date, no viral gill infections of cod have been documented. In this study, we collected samples from three sequential time points in summer 2023 from
Mona C. Gjessing, Torstein Tengs, Hanne Nilsen, Saima Mohammad, Simon C. Weli   +4 more
wiley   +1 more source

Cardiac fibrosis induced by high‐fat diet in ApoE‐deficient male mice is exacerbated by genetic deletion of PACAP–PAC1 signaling

Journal of Neuroendocrinology, EarlyView.
Abstract Cardiac fibrosis is characterized by an excessive accumulation of extracellular matrix proteins and occurs in a variety of cardiac diseases, such as the highly prevalent syndrome heart failure with preserved ejection fraction (HFpEF) and other cardiac disorders.
J. M. Schubart, M. K. H. Schaefer, G. A. Bonaterra, L. Mey, H. Schwarzbach, S. Pankuweit, F. Ausbuettel, L. E. Eiden, S. Weyand, E. Weihe, R. Kinscherf, C. Waechter   +11 more
wiley   +1 more source

Risk factors associated with sudden death vs. congestive heart failure or arterial thromboembolism in cats with hypertrophic cardiomyopathy [PDF]

, 2016
Borgeat, K A, Brodbelt, D C, Connolly, D J, Fuentes, V L, Payne, J R   +4 more
core   +1 more source

CD36 and Its Role in Obesity

Obesity Reviews, EarlyView.
ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia, Maiken Mellergaard, Carlos Salomon, Pilar Sepulveda, Peter Kristensen, Aase Handberg   +5 more
wiley   +1 more source

New cases expand the genotype, phenotype and therapeutic landscape of H syndrome

British Journal of Haematology, EarlyView.
Clément Triaille, Julie Beauchemin, Philippe M. Campeau, Hugo Chapdelaine, Julie Dery, Maria Kondyli, Grant Mitchell, Julie Powell, Sophie Turpin, Guilhem Cros, Fabien Touzot   +10 more
wiley   +1 more source