Results 111 to 120 of about 125,918 (262)
CellsHypertrophic scars are characterized by excessive collagen deposition, fibrotic remodeling, and functional impairment. However, the ability of current models is limited in recapitulating human pathology. This study presents a novel approach using induced
Hyun Mi Kim +4 more
doaj +1 more source
Recent Advances in Cryogel Applications for Musculoskeletal Regeneration
Medicinal Research Reviews, EarlyView.ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim +4 more
wiley +1 more source
Advanced ScienceInspired by the scar‐free wound healing in infants, an anti‐scar strategy is proposed by accelerating wound healing using silicate bioactive materials.
Zhaowenbin Zhang +10 more
doaj +1 more source
CLC-3 regulates TGF-β/smad signaling pathway to inhibit the process of fibrosis in hypertrophic scar
HeliyonObjective: To study the role and mechanism of chloride channel-3 (ClC-3) in the formation of hypertrophic scar by constructing ClC-3 interference vectors and examining their effects on human hypertrophic scar fibroblasts (HSFB).
Qian Liang +8 more
doaj +1 more source
Potential cellular and molecular causes of hypertrophic scar formation
, 2009 A scar is an expected result of wound healing. However, in some individuals, and particularly in burn victims, the wound healing processes may lead to a fibrotic hypertrophic scar, which is raised, red, inflexible and responsible for serious functional ...
Bloemen, Monica C. T. +14 more
core +1 more source
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
Medicinal Research Reviews, EarlyView.ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis
Redox BiologySkin pan-fibrosis diseases—such as hypertrophic scar (HS), keloid scar (KS), and systemic sclerosis (SSc)—pose significant threats to patients' health and quality of life.
Jianzhang Wang +8 more
doaj +1 more source
, 2016 (A) Macroscopic images of human hypertrophic scar (HTS) grafted onto the back of immunocompromized Nude mice at week 7 (w7) at the time of cell injection (upper panels).
Marie-Catherine Vozenin (342271) +9 more
core +1 more source
Redefining Acne as a Distinct Inflammatory Disease: Acne Is Not an Aesthetic Issue
JEADV Clinical Practice, EarlyView.
Jean Paul Claudel +4 more
wiley +1 more source
Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley +1 more source