Results 71 to 80 of about 125,918 (262)

Hsa_circ_0008667 exerts a mediating effect on the hypertrophic scar-associated fibroblast functions through targeting miR-324-5p/HOXA9

Türk Biyokimya Dergisi
Hypertrophic scar (HS), a type of pathological scar, arises from excessive fibrosis in the process of skin wound repair. Circular RNAs (circRNAs) are involved in regulating fibroblast functions in HS, but the role of circ_0008667 remains unclear.
Miao Xiaolin, Zhang Suwen
doaj   +1 more source

Treatment of Hypertrophic Scar in Human with Autologous Transplantation of Cultured Keratinocytes and Fibroblasts along with Fibrin Glue [PDF]

Cell Journal, 2015
Objective: Hypertrophic scar involves excessive amounts of collagen in dermal layer and may be painful. Nowadays, we can’t be sure about effectiveness of procedure for hypertrophic scar management.
Ehsan Taghiabadi, Parvaneh Mohammadi, Nasser Aghdami, Nasrin Falah, Zahra Orouji, Abdoreza Nazari, Saeed Shafieyan   +6 more
doaj  

Human hypertrophic and keloid scar models: principles, limitations and future challenges from a tissue engineering perspective

, 2014
Most cutaneous wounds heal with scar formation. Ideally, an inconspicuous normotrophic scar is formed, but an abnormal scar (hypertrophic scar or keloid) can also develop.
Niessen, F.B., Frank B. Niessen, Lenie J. van den Broek, Susan Gibbs, Grace C. Limandjaja, van den Broek, L.J., Gibbs, S., Limandjaja, G.C.   +7 more
core   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

2 - Medical Scar Management

The treatment of hypertrophic scars and keloids can be difficult. Herein, the authors describe the available data for many scar therapies including pressure and compression therapy, massage therapy, photoprotection, silicone gel and sheets, onion extract,
Riopelle, Alexandria M., Hooper, Perry Basil, Eber, Ariel E., Rohrer, Thomas E.   +3 more
core   +1 more source

Assembly and Maintenance of Myofibrils in the Heart

Cytoskeleton, EarlyView.
ABSTRACT The assembly of actin and myosin to the paracrystalline arrangement of myofibrils in striated muscle, that is, heart and skeletal, has puzzled many a cell biologist. Different models, based on cultured cardiomyocytes, were proposed for the last 30 years to explain the sequence of events.
Elisabeth Ehler
wiley   +1 more source

Combined fractional carbon dioxide laser with long pulsed Nd:YAG laser for treatment of immature hypertrophic scar

Journal of the Egyptian Women’s Dermatologic Society
Background Immature hypertrophic scar complicated with contracture, disability, disfigurement, social embarrassment, pain, itching, residual scar, and prolonged maturation period.
Zaynab S. Keshk, Manal M. Salah, Neiven A. Samy   +2 more
doaj   +1 more source

Effect of TAT-rhbFGF on the index of hypertrophic scar thickness.

, 2015
Note: Data are presented as the mean±SD.* Compared with the control ...
Long Zheng (694761), Xiaojie Wang (166442), Xuechao Jia (694760), Ting Yang (189879), Xiaokun Li (166455), Haishan Tian (494919), Lu Tang (655389), Peng Lin (251745), Lulu Zheng (694762), Bingjie Yu (694763), Zhitao Wang (563389)   +10 more
core   +1 more source

Zebrafish inversin mutants develop scoliosis in the absence of laterality defects

Developmental Dynamics, EarlyView.
Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick, Lorraine Eley, Deborah J. Henderson, Bill Chaudhry   +3 more
wiley   +1 more source

Burns, hypertrophic scar and galactorrhea

Journal of Injury and Violence Research, 2013
An 18-year-old woman was admitted to Motahari Burn Center suffering from 30% burns. Treatment modalities were carried out for the patient and she was discharged after 20 days. Three to four months later she developed hypertrophic scar on her chest and upper limbs. At the same time she developed galactorrhea in both breasts and had a disturbed menstrual
Karimi, Hamid, Nourizad, Samad, Momeni, Mahnoush, Rahbar, Hosein, Momeni, Mazdak, Farhadi, Khosro   +5 more
openaire   +3 more sources