Results 41 to 50 of about 760,497 (383)

Emerging Roles of Neuronal Ca2+ Sensor-1 in Cardiac and Neuronal Tissues: A Mini Review

Frontiers in Molecular Neuroscience, 2019
The EF-hand calcium (Ca2+)-binding protein, neuronal Ca2+ sensor-1 (NCS-1/frequenin), is predominantly expressed in neuronal tissues and plays a crucial role in neuronal functions, including synaptic transmission and plasticity.
Tomoe Y. Nakamura, Shu Nakao, Shu Nakao, Shigeo Wakabayashi, Shigeo Wakabayashi   +4 more
doaj   +1 more source

Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States

Cell Reports, 2020
Summary: Loading of skeletal muscle changes the tissue phenotype reflecting altered metabolic and functional demands. In humans, heterogeneous adaptation to loading complicates the identification of the underpinning molecular regulators.
Tanner Stokes, James A. Timmons, Hannah Crossland, Thomas R. Tripp, Kevin Murphy, Chris McGlory, Cameron J. Mitchell, Sara Y. Oikawa, Robert W. Morton, Bethan E. Phillips, Steven K. Baker, Phillip J. Atherton, Claes Wahlestedt, Stuart M. Phillips   +13 more
doaj   +1 more source

Weight Pulling: A Novel Mouse Model of Human Progressive Resistance Exercise

Cells, 2021
This study describes a mouse model of progressive resistance exercise that utilizes a full-body/multi-joint exercise (weight pulling) along with a training protocol that mimics a traditional human paradigm (three training sessions per week, ~8–12 ...
Wenyuan G. Zhu, Jamie E. Hibbert, Kuan Hung Lin, Nathaniel D. Steinert, Jake L. Lemens, Kent W. Jorgenson, Sarah M. Newman, Dudley W. Lamming, Troy A. Hornberger   +8 more
doaj   +1 more source

Preliminary definitions for the sonographic features of synovitis in children [PDF]

, 2016
Objectives Musculoskeletal ultrasonography (US) has the potential to be an important tool in the assessment of disease activity in childhood arthritides. To assess pathology, clear definitions for synovitis need to be developed first.
Backhaus, M, Balint, P, Bruns, A, Bruyn, Ga, Collado, P, D'Agostino, Ma, De la Cruz, L, Guillaume Czitrom, S, Herlin, T, Hernandez, C, Iagnocco, Annamaria, Jousse Joulin, S, Lanni, S, Lilleby, V, Magni Manzoni, S, Malattia, C, Modesto, C, Naredo, E., Narrodi, A, Nieto, Jc, Ohrndorf, S, Ravagnani, V, Rossi, L, Roth, J, Selvaag, Am, Swen, N, Ting, T, Tzaribachev, N, Vega Fernandez, P, Vojinovic, J, Windschall, D   +30 more
core   +2 more sources

Adenotonsillar Hypertrophy in Pre-School Children with Sickle Cell Disease and Diagnostic Accuracy of the Sleep Disturbance Scale for Children

International Archives of Otorhinolaryngology, 2018
Introduction Adenotonsillar hypertrophy is more common in children with sickle cell disease, and can lead to sleep-disordered breathing. Objectives To determine the frequency of adenotonsillar hypertrophy in pre-school children with sickle ...
Carlos Rodolfo Tavares de Góis, Jeferson Sampaio D'Ávila, Rosana Cipolotti, Amanda da Silva Lira, Ana Letícia Leite Silva   +4 more
doaj   +1 more source

Significance of MEF2C and RUNX3 Regulation for Endochondral Differentiation of Human Mesenchymal Progenitor Cells

Frontiers in Cell and Developmental Biology, 2020
Guiding progenitor cell development between chondral versus endochondral pathways is still an unachieved task of cartilage neogenesis, and human mesenchymal progenitor cell (MPC) chondrogenesis is considered as a valuable model to better understand ...
Simon I. Dreher, Jennifer Fischer, Tilman Walker, Solvig Diederichs, Wiltrud Richter   +4 more
doaj   +1 more source

The N6-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy

Circulation, 2018
Background: N6-Methyladenosine (m6A) methylation is the most prevalent internal posttranscriptional modification on mammalian mRNA. The role of m6A mRNA methylation in the heart is not known. Methods: To determine the role of m6A methylation in the heart,
L. Dorn, Lior Lasman, J. Chen, Xianyao Xu, T. Hund, M. Medvedovic, J. Hanna, Jop H. van Berlo, F. Accornero   +8 more
semanticscholar   +1 more source

Soluble ST2 levels and left ventricular structure and function in patients with metabolic syndrome [PDF]

, 2016
Background: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family.
Beunza, Maite, Cardelli, Patrizia, Celic, Vera, Di Somma, Salvatore, Escribano, Elena, Floridi, Federico, Lopez-Andres, Natalia, Magrini, Laura, Majstorovic, Anka, Marino, Rossella, Melero, Amaia, Pencic-Popovic, Biljana, Roy, Ignacio, Salerno, Gerardo, Sljivic, Aleksandra   +14 more
core   +1 more source

Ventricular androgenic-anabolic steroid-related remodeling: an immunohistochemical study [PDF]

, 2017
Background: Several fatal cases of bodybuilders, following a myocardial infarction after long exposure to androgenicanabolic steroids (AAS), are reported. In recent years, evidence has emerged of cases of heart failure related to AAS consumption, with no
Cecchi, Rossana, Ciallella, Costantino, DI LUCA, Natale Mario, Kimura, Akihiko, Kondo, Toshikazu, Muciaccia, Barbara, Nosaka, Mizuho, Sestili, Cristina   +7 more
core   +1 more source

ERK: A Key Player in the Pathophysiology of Cardiac Hypertrophy

International Journal of Molecular Sciences, 2019
Cardiac hypertrophy is an adaptive and compensatory mechanism preserving cardiac output during detrimental stimuli. Nevertheless, long-term stimuli incite chronic hypertrophy and may lead to heart failure. In this review, we analyze the recent literature
Simona Gallo, Annapia Vitacolonna, A. Bonzano, P. Comoglio, T. Crepaldi   +4 more
semanticscholar   +1 more source