Results 101 to 110 of about 70,452 (325)
Nutrix Journal, 2022 Background Studies have shown that a direct association exists between the diet and blood uric acid concentrations. However, works on the association of dietary patterns with blood uric acid concentrations and hyperuricemia remain limited.
Mei-rong Zhou +7 more
semanticscholar +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract Dazukibart is a humanized monoclonal antibody selectively targeting interferon‐β. The pharmacokinetics (PK), safety, tolerability, and immunogenicity of dazukibart were evaluated in 2 double‐blind, randomized, placebo‐controlled, single‐dose, Phase 1 studies in healthy adults in China (Study 1: N = 18; dazukibart 900 mg = 15; placebo = 3) and ...
Naihan Chen +10 more
wiley +1 more source
Spatiotemporal gait parameters and plantar pressure distribution during barefoot walking in people with gout and asymptomatic hyperuricemia: comparison with healthy individuals with normal serum urate concentrations [PDF]
, 2016 Background To identify spatiotemporal gait parameters and plantar pressure distribution during barefoot walking in people with gout and people with asymptomatic hyperuricemia by comparing them to healthy individuals with normal serum urate ...
Dalbeth, N +3 more
core +2 more sources
Major adverse cardiovascular events and hyperuricemia during tuberculosis treatment.
PLoS ONE, 2023 BackgroundHyperuricemia is common during tuberculosis (TB) treatment, especially in association with pyrazinamide (PZA). This study investigated the relationship between major adverse cardiovascular events (MACEs) and hyperuricemia during TB treatment ...
Hong-Joon Shin +9 more
doaj +1 more source
Arthritis & Rheumatology, 2022 In gout, hyperuricemia promotes urate crystal deposition, which stimulates the NLRP3 inflammasome and interleukin‐1β (IL‐1β)–mediated arthritis. Incident gout without background hyperuricemia is rarely reported.
Khaled A. Elsaid +21 more
semanticscholar +1 more source
Gout in pregnancy: Obstetric and neonatal outcomes
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar +3 more
wiley +1 more source
Patients Prescribed Anakinra for Acute Gout Have Baseline Increased Burden of Hyperuricemia, Tophi, and Comorbidities, and Ultimate All-Cause Mortality. [PDF]
, 2019 Objective:The interleukin-1 (IL-1) receptor antagonist anakinra is an effective, off-label option in acute gout flares, when conventional therapy options are narrowed.
Pedersen, Brian +2 more
core
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population [PDF]
, 2018 Chronic kidney disease and hyperuricemia are serious global health problems. Recent genome-wide association studies have identified various genetic variants related to these disorders. However, most studies have been conducted in a cross-sectional manner.
Fujimaki Tetsuo +8 more
core +2 more sources
Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females
iMetaOmics, EarlyView.Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang +8 more
wiley +1 more source
Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout. [PDF]
, 2019 ObjectiveLesinurad (LESU) is a selective urate reabsorption inhibitor approved at 200 mg daily for use with a xanthine oxidase inhibitor (XOI) to treat hyperuricaemia in gout patients failing to achieve target serum urate on XOI. The aim of the study was
Baumgartner, Scott +8 more
core +1 more source