Results 131 to 140 of about 70,452 (325)

Predictors of systemic sclerosis patients with interstitial lung disease progression: A retrospective study

Rheumatology &Autoimmunity, EarlyView.
The final systemic sclerosis patients with interstitial lung disease (SSc‐ILD) progression prediction model was composed of 6 significant risk factors: male, type 2 diabetes mellitus, pericardial effusion, anti‐Ro52, hypoproteinemia, and elevated C‐reactive protein. Our model demonstrated excellent prognostic utility.
Xi Cao, Shanshan Wang, Wenyi Yuan, Mian Liu, Xiaoyan Xin, Xiang Fang, Dandan Wang   +6 more
wiley   +1 more source

Overweight and Obesity-related Metabolic Disorders in Hospital Employees [PDF]

, 2006
BackgroundObesity is associated with metabolic disorders and cardiovascular diseases. This study investigated the relationship between overweight and obese status and the incidence of type 2 diabetes, hypertension, hyperlipidemia and hyperuricemia ...
Chen, Tony Hsiu-Hsi, Hwang, Lee-Ching, Tsai, Cheng-Ho   +2 more
core   +1 more source

The effectiveness and safety of azvudine treatment in COVID‐19 patients with kidney disease based on a multicenter retrospective cohort study

VIEW, EarlyView.
A retrospective, multicenter cohort study was conducted across nine hospitals in Henan Province, aiming to evaluate the efficacy and safety of azvudine in hospitalized COVID‐19 patients with kidney disease. Through the application of Kaplan‒Meier and multivariate Cox regression analyses, it was found that azvudine may have potential effects in reducing
Bo Yu, Mengzhao Yang, Jia Yu, Daming Wang, Hong Luo, Ming Cheng, Shixi Zhang, Guotao Li, Ling Wang, Guowu Qian, Donghua Zhang, Silin Li, Zhigang Ren, Quancheng Kan   +13 more
wiley   +1 more source

Urate Handling in the Human Body [PDF]

, 2016
Elevated serum urate concentration is the primary cause of gout. Understanding the processes that affect serum urate concentration is important for understanding the etiology of gout and thereby understanding treatment. Urate handing in the human body is
David Hyndman, Jeffrey N. Miner, Sha Liu
core   +1 more source

Real‐world safety and effectiveness of guselkumab in patients with psoriasis: A post‐marketing surveillance study through up to week 52 in Japan

The Journal of Dermatology, EarlyView.
Abstract Guselkumab is a monoclonal antibody that binds to the p19 subunit of interleukin‐23 and inhibits its downstream signaling. The safety profile of guselkumab and its superior efficacy over placebo and adalimumab for the treatment of patients with moderate‐to‐severe psoriasis were reported in phase 3 studies conducted within and outside Japan. To
Yayoi Tada, Yukako Sugiura, Manami Kamishima, Shoya Takahashi, Yoshihito Tanaka, Junya Masuda, Keiichi Yamanaka   +6 more
wiley   +1 more source

Concordance of gout management with European League against Rheumatism recommendations in hospital practice [PDF]

, 2010
Aim: To assess the concordance of gout management with the European League Against Rheumatism (EULAR) gout recommendations in hospital practice. Methods: This was a retrospective review of case notes of patients presenting to rheumatology outpatients ...
Attard Cortis, Petramay, Borg, Andrew A., Coleiro, Bernard, Mercieca, Cecilia   +3 more
core  

Deucravacitinib, an Oral, Selective, Allosteric Tyrosine Kinase 2 Inhibitor, in Japanese Patients With Plaque Psoriasis: In‐Depth Analysis of Efficacy and Safety in the Phase 3 POETYK PSO‐4 Trial

The Journal of Dermatology, EarlyView.
ABSTRACT Deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor, is approved in Japan for adults with plaque, generalized pustular, and erythrodermic psoriasis who have inadequate response to conventional systemic therapies. In the Phase 3, open‐label POETYK PSO‐4 (NCT03924427) trial, deucravacitinib was efficacious and well ...
Yukari Okubo, Akimichi Morita, Shinichi Imafuku, Yayoi Tada, Katsuki Tsuritani, Yanqiu Shao, Zoran Popmihajlov, Andrew Napoli, Lauren Hippeli, Katsuyoshi Habiro, Mamitaro Ohtsuki   +10 more
wiley   +1 more source

Prevalensi Hiperurisemia Pada Remaja Obes Di Smk Negeri 1 Bitung [PDF]

, 2013
Uric acid is an end product of purine metabolism of substances derived from the rest of the food we eat. Substances contained in any materials purine foods we eat both animals and plants.
Kepel, B. (Billy), Manampiring, A. (Aaltje), MONANGIN, P. (PRILLY)   +2 more
core  

The independent association between parathyroid hormone levels and hyperuricemia: a national population study [PDF]

, 2012
Introduction: Increased frequencies of hyperuricemia and gout have been associated with primary hyperparathyroidism, and recent clinical trials of parathyroid hormone (PTH) have reported hyperuricemic adverse events. We evaluated the potential population
Choi, Hyon K, Choi, Jee Woong, Hui, Janet Y, Mount, David Bruce, Zhang, Yuqing, Zhu, Yanyan   +5 more
core   +1 more source

Lower time‐averaged serum uric acid was associated with increased mortality in peritoneal dialysis patients

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 479-490, June 2025.
Abstract Background The relationship between time‐averaged serum uric acid (TA‐SUA) levels and prognosis in peritoneal dialysis (PD) patients are rarely discussed. Methods This was a retrospective cohort study. PD patients recruited from January 1, 2011, to December 31, 2020, were included.
Lu Li, Hongxia Zhang, Botao Zhang, Fangyuan Yang, Mengting Wang, Wenlong Qiu, Lina Fu, Menghua Chen, Na Tian   +8 more
wiley   +1 more source