Results 21 to 30 of about 77,229 (288)
Introduction: The prevalence of hyperuricemia is increasing world widely; the understanding of population attributable faction of modifiable risk factors is important for disease prevention.
Huijing He +14 more
doaj +1 more source
Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]
BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc +12 more
core +2 more sources
The Role of the Intestine in the Development of Hyperuricemia
Gout is a common inflammatory arthritis caused by the deposition of sodium urate crystals in the joints. Hyperuricemia is the fundamental factor of gout.
Hui-ming Yin, Na Liu, Jie Chen
semanticscholar +1 more source
Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]
Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio +9 more
core +1 more source
The Role of Oxidative Stress in Hyperuricemia and Xanthine Oxidoreductase (XOR) Inhibitors
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic disease caused by the increased formation or reduced excretion of serum uric acid (SUA).
Ning Liu +8 more
semanticscholar +1 more source
PurposeThe purpose of this study is to investigate the effect of asymptomatic hyperuricemia on mortality of elderly patients with coronary artery disease (CAD) after elective percutaneous coronary intervention (PCI).MethodsOne thousand two hundred ninety-
Chen Chen +5 more
doaj +1 more source
Hyperuricemia is another common metabolic disease, which is considered to be closely related to the development of many chronic diseases, in addition to the “three highs.” Currently, although drugs show positive therapeutic effects, they have been shown ...
Cheng-yuan Wang, Jian-gang Dai
semanticscholar +1 more source
Objective This investigation sought to elucidate the potential correlation between a recently characterized adiposity metric, termed the Weight-Adjusted-Waist Index (WWI) and hyperuricemia.
Yunyi Ding +5 more
semanticscholar +1 more source
Recent studies into the beneficial effects of fermented foods have shown that this class of foods are effective in managing hyperuricemia and gout.
Ying Wu +9 more
semanticscholar +1 more source
Uric acid is more strongly associated with impaired glucose regulation in women than in men from the general population: the KORA F4-Study. [PDF]
High serum uric acid (UA) levels are associated with the metabolic syndrome, type 2 diabetes and cardiovascular disease. It is largely unknown whether there are gender-specific differences regarding the association between UA and prediabetic states.
Döring, Angela +5 more
core +10 more sources

