Results 21 to 30 of about 57,118 (288)

Does obesity modify the epidemiological association between hyperuricemia and the prevalence of hypertension among Northern Chinese community-dwelling people? A Chinese population-based study

BMJ Open, 2019
Objectives Hyperuricemia and obesity both play a role in the development of hypertension. However, limited evidence is available for the combined effect of hyperuricemia and obesity on the prevalence of hypertension in the Chinese population. We aimed to
Simiao Tian, Yazhuo Liu, Ao Feng, Yang Xu   +3 more
doaj   +1 more source

Identification of four genes as novel susceptibility loci for early‑onset type 2 diabetes mellitus, metabolic syndrome, or hyperuricemia [PDF]

, 2018
Given that early‑onset type 2 diabetes mellitus (T2DM), metabolic syndrome (MetS), and hyperuricemia have been shown to have strong genetic components, the statistical power of a genetic association study may be increased by focusing on early‑onset ...
Fujimaki Tetsuo, Horibe Hideki, Kato Kimihiko, Oguri Mitsutoshi, Sakuma Jun, Takeuchi Ichiro, Yamada Yoshiji, Yasukochi Yoshiki, 佐久間 淳   +8 more
core   +2 more sources

Clinicopathological Characteristics, Role of Immunosuppressive Therapy and Progression in IgA Nephropathy with Hyperuricemia

Kidney & Blood Pressure Research, 2018
Background/Aims: The aim of the study was to investigate clinicopathological characteristics, the role of immunosuppressive therapy and renal outcome in IgA nephropathy (IgAN) patients with hyperuricemia.
Yiping Ruan, Fuyuan Hong, Jiabin Wu, Miao Lin, Chen Wang, Fayang Lian, Fang Cao, Guokai Yang, Meizhu Gao   +8 more
doaj   +1 more source

Association of hypertension and hypertriglyceridemia on incident hyperuricemia: an 8-year prospective cohort study

Journal of Translational Medicine, 2020
Background Hypertension and high triglyceride are two of the most important risk factors for hyperuricemia. Epidemiological records show that hypertension and dyslipidemia often coexist and may significantly increase the risk of target organ damage ...
Yuan Zhang, Miaomiao Zhang, Xiawen Yu, Fengjiang Wei, Chen Chen, Kai Zhang, Shuzhi Feng, Yaogang Wang, Wei-Dong Li   +8 more
doaj   +1 more source

Gouty arthritis of the spine in a renal transplant patient : a clinical case report: an unusual presentation of a common disease [PDF]

, 2015
Axial gout is a well-documented but uncommon manifestation of gout. Its mimicking nature and the impracticality of axial joint aspiration might considerably delay its diagnosis.
Dhaese, Sofie, STRYCKERS, MARIJKE, Terryn, Wim, VAN DER MEERSCH, HANS, Van Laecke, Steven   +4 more
core   +1 more source

Composite Dietary Antioxidant Index Is Negatively Associated with Hyperuricemia in US Adults: An Analysis of NHANES 2007–2018

International Journal of Endocrinology, 2023
Hyperuricemia and its complications are severe risks to human health. Dietary intervention is considered an essential part of the management of hyperuricemia.
Zhenzong Lin, Haokai Chen, Qiwen Lan, Yinghan Chen, Wanzhe Liao, Xuguang Guo   +5 more
doaj   +1 more source

Uric acid enhances longevity and endurance and protects the brain against ischemia [PDF]

, 2020
Among mammals, there is a positive correlation between serum uric acid (UA) levels and life span. Humans have high levels of UA because they lack a functional urate oxidase (UOX) enzyme that is present in shorter lived mammals.
Argüelles Castilla, Sandro, Camandola, Simonetta, Cutler, Roy G., Feldman, Neil H., Haran, James B., Mattsona, Mark P., Seon Yoon, Jeong   +6 more
core   +1 more source

Comorbidities in aging patients with sickle cell disease. [PDF]

, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

Identification of C21orf59 and ATG2A as novel determinants of renal function-related traits in Japanese by exome-wide association studies [PDF]

, 2017
journal ...
Arai Tomio, Fujimaki Tetsuo, Fujiwara Yoshinori, Horibe Hideki, Kato Kimihiko, Kawai Hisashi, Mori Seijiro, Muramatsu Masaaki, Obuchi Shuichi, Oguri Mitsutoshi, SAKUMA Jun, Sawabe Motoji, Shinkai Shoji, Takeuchi Ichiro, Tanaka Masashi, Taniguchi Yu, Yamada Yoshiji, Yasukochi Yoshiki   +17 more
core   +2 more sources

Exploration of molecular biomarkers in ankylosing spondylitis transcriptomics

Frontiers in Immunology
BackgroundInflammation of the spine and sacroiliac joints is a hallmark of the chronic, progressive inflammatory illness known as ankylosing spondylitis (AS). The insidious onset and non-specific early symptoms of AS often lead to delays in diagnosis and
Yuanpiao Ni, Yuanpiao Ni, Linrui Zhong, Linrui Zhong, Yanhui Li, Yanhui Li, Zeng Zhang, Zeng Zhang, Bin Ming, Bin Ming, Yufeng Qing, Yufeng Qing, Quanbo Zhang, Quanbo Zhang   +13 more
doaj   +1 more source