Results 21 to 30 of about 26,902 (99)

Potential Probiotic Lacticaseibacillus paracasei MJM60396 Prevents Hyperuricemia in a Multiple Way by Absorbing Purine, Suppressing Xanthine Oxidase and Regulating Urate Excretion in Mice

Microorganisms, 2022
Hyperuricemia is a metabolic disorder caused by increased uric acid (UA) synthesis or decreased UA excretion. Changes in eating habits have led to an increase in the consumption of purine-rich foods, which is closely related to hyperuricemia.
Youjin Lee, Pia Werlinger, J. Suh, Jinhua Cheng   +3 more
semanticscholar   +1 more source

Hyperuricemia and its related diseases: mechanisms and advances in therapy

Signal Transduction and Targeted Therapy
Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic syndrome, and diabetes, etc.
Lin Du, Yao Zong, Haorui Li, Qiyue Wang, Lei Xie, Bo Yang, Yidan Pang, Changqing Zhang, Zhigang Zhong, Junjie Gao   +9 more
semanticscholar   +1 more source

Noninvasive and Individual‐Centered Monitoring of Uric Acid for Precaution of Hyperuricemia via Optical Supramolecular Sensing

Advancement of science, 2022
Characterized by an excessively increased uric acid (UA) level in serum, hyperuricemia induces gout and also poses a great threat to renal and cardiovascular systems.
Yaping Zhang, Huijuan Yu, Shiwei Chai, X. Chai, Luyao Wang, Wen-Chao Geng, Juan-juan Li, Yu‐Xin Yue, Dong‐sheng Guo, Yuefei Wang   +9 more
semanticscholar   +1 more source

Plasma aldosterone concentrations elevation in hypertensive patients: the dual impact on hyperuricemia and gout

Frontiers in Endocrinology
Background Prior research has highlighted the association between uric acid (UA) and the activation of the renin-angiotensin-aldosterone system (RAAS).
Shuaiwei Song, Xintian Cai, Junli Hu, Qing Zhu, Di Shen, Huimin Ma, Yingying Zhang, Rui Ma, Pan Zhou, Wenbo Yang, Jing Hong, Delian Zhang, Nanfang Li   +12 more
semanticscholar   +1 more source

Relationship between gout, hyperuricemia, and obesity—does central obesity play a significant role?—a study based on the NHANES database

Diabetology & Metabolic Syndrome
Background Our objective was to evaluate how various measures of obesity, such as body mass index(BMI), body roundness index(BRI), and weigh adjusted waist index(WWI), influence urate levels, prevalence of gout and to compare the disparities among these ...
Tongjun Mao, Qian He, Junping Yang, Lanlan Jia, Guofei Xu   +4 more
semanticscholar   +1 more source

The biomarkers discovery of hyperuricemia and gout: proteomics and metabolomics

PeerJ, 2022
Background Hyperuricemia and gout are a group of disorders of purine metabolism. In recent years, the incidence of hyperuricemia and gout has been increasing, which is a severe threat to people’s health.
Xinghong Wu, Chongge You
semanticscholar   +1 more source

Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease

Frontiers in Pharmacology, 2022
Hyperuricemia is a common biochemical disorder, which resulted from both excessive uric acid (UA) production and/or absolute or relative impairment of urinary UA excretion.
Le-tian Yang, Bo Wang, Liang Ma, P. Fu
semanticscholar   +1 more source

Assessing the Causal Relationships Between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization

Arthritis & Rheumatology, 2021
Hyperuricemia is closely associated with insulin resistance syndrome (and its many cardiometabolic sequelae); however, whether they are causally related has long been debated.
N. McCormick, Mark J. O’Connor, C. Yokose, T. Merriman, D. Mount, A. Leong, Hyon K. Choi   +6 more
semanticscholar   +1 more source

The Interaction Between Dietary Fructose and Gut Microbiota in Hyperuricemia and Gout

Frontiers in Nutrition, 2022
With the worldwide epidemics of hyperuricemia and associated gout, the diseases with purine metabolic disorders have become a serious threat to human public health.
Xin-yu Fang, Liang-wei Qi, Hailu Chen, Peng Gao, Qin Zhang, Ruixue Leng, Yin-Guang Fan, Bao-Zhu Li, Hai-Feng Pan, D. Ye   +9 more
semanticscholar   +1 more source

Hyperuricemia—a serious complication among patients with chronic kidney disease: a systematic review and meta-analysis

Exploration of Medicine, 2022
Aim: Hyperuricemia as a putative risk factor for chronic kidney disease (CKD) progression remains controversial and debatable. This systematic review aims to explore the prevalence of hyperuricemia among CKD patients worldwide.
I. Rashid, Pooja Katravath, P. Tiwari, S. D’Cruz, S. Jaswal, G. Sahu   +5 more
semanticscholar   +1 more source