Results 31 to 40 of about 57,118 (288)

Obesity-Related Genetic Variants and Hyperuricemia Risk in Chinese Men

Frontiers in Endocrinology, 2019
Objective: Obesity/metabolic syndrome and hyperuricemia are clinically associated; however, the association of obesity/metabolic syndrome-related genetic variants with hyperuricemia is not clear.
Zhimin Ma, Yunfeng Wang, Yunfeng Wang, Chaonan Xu, Chaonan Xu, Feiling Ai, Feiling Ai, Ling Huang, Jieping Wang, Ji Peng, Yanming Zhou, Yanming Zhou, Meihua Yin, Meihua Yin, Shan Zhang, Shan Zhang, Xinghua Yang, Xinghua Yang   +17 more
doaj   +1 more source

Hyperuricemia predicts increased cardiovascular events in patients with chronic coronary syndrome after percutaneous coronary intervention: A nationwide cohort study from Japan

Frontiers in Cardiovascular Medicine, 2023
BackgroundThe causal relationship between hyperuricemia and cardiovascular diseases is still unknown. We hypothesized that hyperuricemic patients after percutaneous coronary intervention (PCI) had a higher risk of major adverse cardiovascular events ...
Naoyuki Akashi, Masanari Kuwabara, Tetsuya Matoba, Takahide Kohro, Yusuke Oba, Tomoyuki Kabutoya, Yasushi Imai, Kazuomi Kario, Arihiro Kiyosue, Yoshiko Mizuno, Kotaro Nochioka, Masaharu Nakayama, Takamasa Iwai, Yoko Nakao, Yoshitaka Iwanaga, Yoshihiro Miyamoto, Masanobu Ishii, Taishi Nakamura, Kenichi Tsujita, Hisahiko Sato, Hideo Fujita, Ryozo Nagai   +21 more
doaj   +1 more source

Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways. [PDF]

Endocrinol Diabetes Metab
Elevated SUA can lead to oxidative stress, endothelial dysfunction, inflammation and impaired function of adipocytes—all of which collectively impede insulin receptor activity and downstream signalling. Key pathways involved include activation of the NLRP3 inflammasome, suppression of AMPK and induction of mitochondrial dysfunction.
Ali N.
europepmc   +2 more sources

Disseminated cutaneous gout: a rare manifestation of a common disease [PDF]

, 2020
Disseminated cutaneous gout is a rare atypical cutaneous manifestation of gout in which widespread dermal and subcutaneous tophi develop at extra-articular body sites.
Adler, Brandon L, Crew, Ashley, DeClerck, Brittney, Guzman, Ruben, Peng, David   +4 more
core  

Hyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population

Scientific Reports, 2017
Hyperuricemia is common in China and the relevance of hyperuricemia and cardiovascular disease (CVD) risk has been highlighted, but to date there has been rarely nation-wide study in China. Here, we aim to estimate the current prevalence of hyperuricemia
Jie Wu, Ling Qiu, Xin-qi Cheng, Tao Xu, Wei Wu, Xue-jun Zeng, Yi-cong Ye, Xiu-zhi Guo, Qian Cheng, Qian Liu, Li Liu, Cheng-li Xu, Guang-jin Zhu   +12 more
doaj   +1 more source

Is hyperuricemia an independent risk factor for new-onset chronic kidney disease?: a systematic review and meta-analysis based on observational cohort studies [PDF]

, 2014
This article discusses the role of interrogation in intelligence during the Second World War, and it focuses on the importance of culture in the collection of Human Intelligence in the European theatre of operation.
Ling Li, Chen Yang, Yuliang Zhao, Xiaoxi Zeng, Fang Liu, Ping Fu   +5 more
core   +5 more sources

Hyperuricemia and gout increased the risk of long-term mortality in patients with heart failure: insights from the National Health and Nutrition Examination Survey

Journal of Translational Medicine, 2023
Background The prevalence of hyperuricemia, gout, and heart failure (HF) is on the rise, and these conditions often share similar risk factors. The present study aimed to evaluate the relationship among hyperuricemia, gout, HF, and all-cause mortality ...
Yingdong Han, Yu Cao, Xinxin Han, Hong Di, Yue Yin, Juan Wu, Yun Zhang, Xuejun Zeng   +7 more
doaj   +1 more source

Polymorphisms of the genes ABCG2, SLC22A12 and XDH and their relation with hyperuricemia and hypercholesterolemia in Mexican young adults [version 2; peer review: 2 approved]

F1000Research, 2021
Background: Hyperuricemia is a pathological condition associated with risk factors of cardiovascular disease. In this study, three genetic polymorphisms were genotyped as predisposing factors of hyperuricemia.
Juan Manuel Vargas-Morales, Martha Guevara-Cruz, Celia Aradillas-García, Lilia G. Noriega, Armando Tovar, Jorge Alejandro Alegría-Torres   +5 more
doaj   +1 more source

The independent association between parathyroid hormone levels and hyperuricemia: a national population study [PDF]

, 2012
Introduction: Increased frequencies of hyperuricemia and gout have been associated with primary hyperparathyroidism, and recent clinical trials of parathyroid hormone (PTH) have reported hyperuricemic adverse events. We evaluated the potential population
Choi, Hyon K, Choi, Jee Woong, Hui, Janet Y, Mount, David Bruce, Zhang, Yuqing, Zhu, Yanyan   +5 more
core   +1 more source

Circ_0058051 Targeted miR-129-5P Regulates Autophagy-Related Gene ATG7 to Promote the Inflammation of Gout

Mediators of Inflammation
Gout is a common autoinflammatory disease that clinically manifests as recurrent joint redness, swelling, and pain, but the molecular mechanism of recurrent gouty inflammation remains unclear.
Jianwei Guo, Tianyi Lei, Yi Jiang, Peng Wang, Zeng Zhang, Xiang Yu, Guilin Jian, Quanbo Zhang, Yufeng Qing   +8 more
doaj   +1 more source