Results 91 to 100 of about 19,163 (327)

Alcohol, Medications, and Older Adults [PDF]

open access: yes, 2011
Educational Objectives 1. Describe patterns of simultaneous use of alcohol and Central Nervous System (CNS) - acting medications among older adults. 2.
Mohanty, Mailtreyee, Slattum, Patricia
core   +1 more source

Psychotropic medication use and cognition in institutionalized older adults with mild to moderate dementia [PDF]

open access: yes, 2009
Background: Most studies examining psychotropic medication use on cognition in older persons with dementia include measures of global cognitive function.
Alexopoulos   +16 more
core   +2 more sources

Efficacy and Acceptability of Licensed and Off‐Label Pharmacological Interventions for Insomnia in Patients With Severe Mental Illness: A Systematic Review and Meta‐Analysis of Randomised Trials

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background A wide range of drugs is used to alleviate insomnia symptoms in individuals with severe mental illness (SMI), including licensed drugs and sedating drugs prescribed off‐label. Yet, no review has gathered the evidence on illness‐specific or transdiagnostic outcomes of pharmacological interventions for insomnia.
Nina Friis Bak Fuglsang   +9 more
wiley   +1 more source

Are sedatives and hypnotics associated with increased suicide risk of suicide in the elderly?

open access: yesBMC Geriatrics, 2009
Background While antidepressant-induced suicidality is a concern in younger age groups, there is mounting evidence that these drugs may reduce suicidality in the elderly.
Waern Margda, Carlsten Anders
doaj   +1 more source

Increased use of hypnotics in individuals with celiac disease: A nationwide case-control study [PDF]

open access: yes, 2015
BACKGROUND: Although poor sleep is common in numerous gastrointestinal diseases, data are scarce on the risk of poor sleep in celiac disease. The objective of this study was to estimate the risk of repeated use of hypnotics among individuals with celiac ...
Kotagal, Suresh   +5 more
core   +1 more source

Predicting Response to Pro‐Cognitive Interventions in Mood Disorders: A Systematic Review by the International Society for Bipolar Disorders Targeting Cognition Task Force

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Major depressive disorder (MDD) and bipolar disorder (BD) are often associated with persistent cognitive deficits that impair psychosocial functioning. While pro‐cognitive interventions show promise, trial findings are inconsistent, potentially due to baseline factors influencing treatment response.
Dimosthenis Tsapekos   +30 more
wiley   +1 more source

Focusing on an EEG Biomarker, the Photoparoxysmal Response (PPR), to Identify Promising Investigational Anti‐Seizure Medications (ASMs) and Differentiate the Efficacy of Existing ASMs

open access: yes
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Ronald C. Reed   +1 more
wiley   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

open access: yesAddiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper   +7 more
wiley   +1 more source

Changing trends in drug overdose mortality in Spain, 2001–2022

open access: yesAddiction, EarlyView.
Abstract Aim To measure the evolution of drug overdose mortality in Spain between 2001 and 2022. Design, Setting, Participants A repeated cross‐sectional observational study using nationwide mortality data from Spain, 2001–2022, among individuals aged 15–64 years.
Florencia Giné   +6 more
wiley   +1 more source

Factors associated with high‐dose antipsychotic prescriptions in outpatients with schizophrenia: An analysis of claims data from a Japanese prefecture

open access: yesNeuropsychopharmacology Reports, 2020
Background Antipsychotics are commonly prescribed in high doses in combination with multiple psychotropic drugs. This study focused on the high‐dose antipsychotic prescriptions in patients with schizophrenia, while aiming to identify their associations ...
Tatsuichiro Takahashi   +4 more
doaj   +1 more source

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