Results 121 to 130 of about 25,584 (365)

Prescribing Patterns and Impact of Sedatives in Hospitalized Older Adults: A Secondary Analysis of the MedSafer Study

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background We aimed to examine the impact of sedative prescription patterns in hospitalized older adults on post‐discharge adverse drug events (ADEs), falls, and sleep. Methods We conducted a secondary analysis of the MedSafer randomized controlled trial (RCT; NCT03272607) which included hospitalized adults ≥ 65 years of age who were taking ...
Bennet Desormeau, Allen Huang, James Downar, Peter E. Wu, Emilie Bortolussi‐Courval, Sydney B. Ross, Kiran Battu, Louise Papillon‐Ferland, Finlay A. McAlister, Sarah Elsayed, Marnie Goodwin Wilson, Rodrigo B. Cavalcanti, Emily G. McDonald, Todd C. Lee   +13 more
wiley   +1 more source

Effective and safe pediatric sedation [PDF]

Anesthesia and Pain Medicine
Pediatric sedation is a crucial tool for minimizing pain and anxiety during procedures and examinations in children. However, it is not without risks. This review provides a comprehensive review of pediatric sedation, including both established practices
Young-Eun Jang, Jin-Tae Kim
doaj   +1 more source

Criteria to Report Adverse Drug Withdrawal Events in Clinical Trials: A Systematic Review

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Polypharmacy is a major risk factor for adverse drug events (ADEs), which are a common cause of hospitalization, especially among older adults. Deprescribing is a promising strategy to prevent ADEs; however, clinicians may hesitate to deprescribe for fear of causing adverse drug withdrawal events (ADWEs). Collectively, ADWEs are the
Jimin J. Lee, Émilie Bortolussi‐Courval, Eva Filosa, Soham Rej, Claire Godard‐Sebillote, Robyn Tamblyn, Todd C. Lee, Emily G. McDonald   +7 more
wiley   +1 more source

Chronic insomnia, REM sleep instability and emotional dysregulation: A pathway to anxiety and depression?

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary The world‐wide prevalence of insomnia disorder reaches up to 10% of the adult population. Women are more often afflicted than men, and insomnia disorder is a risk factor for somatic and mental illness, especially depression and anxiety disorders.
Dieter Riemann, Raphael J. Dressle, Fee Benz, Kai Spiegelhalder, Anna F. Johann, Christoph Nissen, Elisabeth Hertenstein, Chiara Baglioni, Laura Palagini, Lukas Krone, Michael L. Perlis, Katharina Domschke, Mathias Berger, Bernd Feige   +13 more
wiley   +1 more source

Pretreatment with Sedative-Hypnotics, but Not with Nondepolarizing Muscle Relaxants, Attenuates Alfentanil-Induced Muscle Rigidity [PDF]

, 1995
Theodore J. Sanford, Matthew B. Weinger, N. Ty Smith, James L. Benthuysen, N. Head, H. Dec Silver, Thomas A. Blasco   +6 more
openalex   +1 more source

A case study approach to understand how quality improvement methods led to improvements in primary care for insomnia [PDF]

, 2011
Context: The Resources for Effective Sleep Treatment (REST) project was conducted in Lincolnshire, UK from 2007-2010. Its aim was to develop and evaluate new approaches to implementing sleep assessment methods and non-pharmacological treatments for ...
Davy, Zowie, Dyas, Jane, Middleton, Hugh, Orner, Roderick, Siriwardena, A. Niroshan, Tilling, Michelle, Togher, Fiona   +6 more
core  

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

An epidemiological survey of drug poisoning and a comparison with other poisonings cases admitted to a university hospital in Gorgan, Iran, 2008-2015 [PDF]

, 2017
Background and aims: Acute drug poisoning is a major public health problem in the world.The aim of this study was to investigate the trends and characteristics of acute drug poisoning and to compare that with other poisonings in Gorgan, Iran.
Delaram, Azam., Hajimohammadi, Amir., Hoseinpoor, Reza., Shayeste, Yaghoub., Shokrzadeh, Mohammad.   +4 more
core  

Respiratory safety of lemborexant in adult and elderly subjects with moderate‐to‐severe chronic obstructive pulmonary disease

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng, Daniel Lorch, Nancy Hall, Margaret Moline   +3 more
wiley   +1 more source

Preliminary feasibility and efficacy of a brief behavioural treatment for insomnia after acquired brain injury: A case series

Journal of Sleep Research, EarlyView.
Summary Insomnia after acquired brain injury (ABI) is common and can negatively impact an individual's rehabilitation, recovery, and quality of life. The present study investigated the feasibility and preliminary efficacy of a Brief Behavioural Treatment for Insomnia (BBTI) in a community sample following ABI. Ten participants were recruited.
Maria Gardani, Satu Baylan, Veronika Zouhar   +2 more
wiley   +1 more source