Results 141 to 150 of about 19,956 (319)

Sedative–hypnotic like effect of 5–methoxyflavone in mice and investigation on possible mechanisms by in vivo and in silico methods

, 2018
Jaikumar Shanmugasundaram, S. Viswanathan, Jagan Nadipelly, Parimala Kathirvelu, Vijaykumar Sayeli, Binoy Varghese Cheriyan   +5 more
openalex   +1 more source

Phenotypic Variability in Slow‐Wave Sleep in Depression: Associations With Clinical Profiles and Disorder Severity

Journal of Sleep Research, EarlyView.
ABSTRACT Slow‐wave sleep (SWS; stage N3) is often reported as reduced in depression, yet variability across depressive phenotypes remains poorly characterised. This study aimed to determine whether N3 architecture—proportion, duration, and latency—identifies clinically distinct profiles in major depressive episode (MDE).
Antoine Salmeron, Pierre A. Geoffroy, Lily Vissouze, Jeanne Leseur, Heloise Rach, Michel Lejoyeux, Justine Frija, Marie Pia d’Ortho, Julia Maruani   +8 more
wiley   +1 more source

Understanding and reducing the prescription of hypnotics and sedatives at the interface of hospital care and general practice: a protocol for a mixed-methods study. [PDF]

BMJ Open, 2016
Heinemann S, Weiß V, Straube K, Nau R, Grimmsmann T, Himmel W, Hummers-Pradier E.   +6 more
europepmc   +1 more source

Benzodiazepines : benefits versus risks [PDF]

, 2007
Benzodiazepines act on the central nervous system and can be prescribed for various medical conditions. They are usually classified by their duration of action.
West, Lorna Marie
core  

Prescription of Psychotropic Drugs for Chronic Insomnia in Primary Care

Journal of Sleep Research, EarlyView.
ABSTRACT Insomnia is the most prevalent sleep disorder in adults, representing a major public health problem. Healthcare management in a specific area first requires analysing its current practices and issues. We conducted a retrospective observational study of over 100,000 patients from two large primary care databases in the public healthcare ...
Jesús Escribá‐Alepuz, Lidia Herrero‐Huertas, María García‐Gil, Estefanía Estévez‐López, Francisco Javier Puertas, Manuel de Entrambasaguas   +5 more
wiley   +1 more source

Pharmaceuticals, except biologicals : 2009 [PDF]

, 2010
Current industrial report.

core  

Development and validation of a prognostic nomogram for predicting of patients with acute sedative-hypnotic overdose admitted to the intensive care unit [PDF]

Guo Tang, T. Zhang, Ping Zhang, Sha Yang, Tao Cheng, Rong Yao   +5 more
openalex   +1 more source

The amnestic and sedative-hypnotic properties of etomidate in mice can be dissociated based on gaba(a) receptor subtype pharmacology [PDF]

, 2006
Beverley A. Orser, Loren Martin, Victor Cheng, John F. MacDonald   +3 more
openalex   +1 more source

Comparative effects of hypnotic agents on sleep architecture and respiratory outcomes in obstructive sleep apnea: A systematic review and network meta‐analysis

Psychiatry and Clinical Neurosciences, EarlyView.
Aim This network meta‐analysis of randomized controlled trials (RCTs) aimed to investigate which hypnotics are associated with the most favorable sleep architecture and respiratory outcomes in adults with obstructive sleep apnea. Methods Primary outcomes included total sleep time (TST) and apnea–hypopnea index (AHI) during TST.
Taro Kishi, Toshikazu Ikuta, Kenji Sakuma, Masakazu Hatano, Tatsuhiko Kishi, Tsuyoshi Kitajima, Nakao Iwata   +6 more
wiley   +1 more source

Anticholinergic and sedative medications use among community dwelling older adults: risk for polypharmacy and poor physical function

BMC Geriatrics
Background Anticholinergic and/or sedative mediations are one of the most commonly prescribed medication groups in older adults. This study aimed to assess the prevalence of anticholinergic and/or sedative mediations use in community dwelling older ...
Aysu Selcuk, Volkan Atmis, Seher Sen, Emine Gemci, Busra Yurumez, Ahmet Yalcin, Asuman Bozkir, Sevgi Aras, Murat Varli   +8 more
doaj   +1 more source