Results 141 to 150 of about 12,153 (246)

Chemical Profiles, Pharmacological Insights, and In Silico Studies of Antidesma montanum Blume: An Experimental and Computer‐Aided Approach

eFood, Volume 7, Issue 4, August 2026.
Antidesma montanum, an edible wild plant, shows notable nutraceutical and pharmacological potential. Methanol extract profiling (GC–MS) identified bioactive metabolites. In vitro, in vivo, and in silico studies demonstrated significant antidiabetic, anthelmintic, anxiolytic, antidepressant, and antidiarrheal activities, supported by strong molecular ...
Naureen Banu, Najmul Alam, Sadia Farid Jhuma, Mohammad Nazmul Islam, Shady A. Alghazali, Md Abdul Awal, Sanjida Islam, Hafsa Siddiqua, Shafinaz Nur, Md. Sohel Rana   +9 more
wiley   +1 more source

Signal Detection Analysis of Hypnotic-induced Respiratory Depression. [PDF]

In Vivo
Hideshima S, Sogawa R, Nakano Y, Mizoguchi Y, Monji A, Shimanoe C.   +5 more
europepmc   +1 more source

Trends and Characteristics of Opioid Use During Pregnancy Between 2010 and 2023: A French Nationwide Drug Utilization Study

European Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background While opioid use during pregnancy has raised concerns worldwide, population‐based data in Europe remain limited. In France, little is known about opioid use in the context of pregnancy. Methods We conducted a nationwide drug utilization study using the French EPI‐MERES Registry, derived from the National Health Data System (SNDS ...
Laurent Chouchana, Philippe Herlemont, Hugo Jourdain, Sara Miranda, Mahmoud Zureik, Rosemary Dray‐Spira   +5 more
wiley   +1 more source

Trends in Hospital Admissions for Psychoactive Substance Intoxication Among Children, Adolescents, and Young Adults in Slovenia, 2013-2023. [PDF]

J Clin Med
Lovrecic B, Simon MR, Lovrecic M.
europepmc   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

Who misuses sedatives for sleep? Evidence from a nationally representative US sample. [PDF]

Sleep Med
Tam K, Sheehan C, Bjorklund E, Milani SA.   +3 more
europepmc   +1 more source

Prevalence of Chronic Pain and Associated Factors Among Nursing Students in Heilongjiang Province, China: A Cross‐Sectional Study

Nursing Open, Volume 13, Issue 8, August 2026.
ABSTRACT Aim This study explored the prevalence and potential factors influencing chronic pain and provided increased theoretical and practical support for future studies on nursing students from a novel perspective. Design This study applied a cross‐sectional study design.
Siqi Liu, Yujin Xie, Zhengxi Chen, Xiwei Chen, Lei Cao, Yue Qin, Mei Yin, Yang Fu, Lei Shi   +8 more
wiley   +1 more source

Changes in psychotropic medication prescription patterns during the COVID-19 pandemic among Japanese children, adolescents and young adults: interrupted time-series study using a national claims database. [PDF]

BJPsych Open
Huang W, Matsui H, Sasabuchi Y, Yasunaga H.   +3 more
europepmc   +1 more source

Metabolite‐Driven Biological Activity of Mandragora autumnalis and Spartium junceum: A Comparative LC‐MS/MS Study on Antioxidant, Cholinesterase, and Carbonic Anhydrase Inhibition

ChemistryOpen, Volume 15, Issue 8, August 2026.
Low‐molecular‐weight phenolic acids in M. autumnalis were associated with antioxidant activity, AChE, and hCA inhibition effects, whereas flavonoid‐rich S. junceum displayed BChE‐oriented inhibition effect and antibacterial activity. LC‐MS/MS‐based metabolite profiling linked distinct chemical compositions to bioactivity patterns, supporting further ...
Kubra Aslan, Esra Elbir, Yusuf Bicakci, Silanur Ozdogan, Mustafa Abdullah Yilmaz, Ilhami Gulcin   +5 more
wiley   +1 more source

Leveraging Administrative Health Data to Capture Rare Adverse Drug Reactions: Identifying Pediatric Patients With Trimethoprim‐Sulfamethoxazole Acute Respiratory Distress Syndrome

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Rare adverse drug reactions (ADRs) are underrecognized and underreported in the electronic medical record (EMR). These events often require clinical review, making systematic identification challenging. The study aim was to develop an approach to prioritize identification and validation of a rare ADR to trimethoprim‐sulfamethoxazole causing ...
Keith Feldman, Jenna O. Miller, Katherine Doane, Laura Loftis, James W. Antoon, Kevin J. Downes, Jennifer L. Goldman   +6 more
wiley   +1 more source