Results 151 to 160 of about 12,153 (246)

Targeting the Carotid Body Function With Big‐K+‐Channel Blocker ENA‐001 in Opioid‐Induced Respiratory Depression: A Scoping Review

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Opioids, most intravenous anesthetics and various illicit substances can cause fatal respiratory depression by depressing central respiratory networks. ENA‐001, a ventilatory modulator targeting the carotid bodies, has emerged as a potential countermeasure without impairing analgesia or hypnosis.
Jimmy J. Arevalo   +9 more
wiley   +1 more source

Association Between Kamikihito Treatment and Nocturnal Voiding Frequency in Patients With Sleep Disturbance: A Retrospective Clinical Study

open access: yesTraditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
ABSTRACT Aim Sleep disturbance is an important contributing factor to nocturia, particularly in older adults. Kamikihito is a Kampo medicine traditionally prescribed for the Heart and spleen systems deficiency pattern (TM1). The aim of this study was to retrospectively evaluate the association between kamikihito treatment and nocturnal voiding ...
Shigehisa Kubota   +7 more
wiley   +1 more source

Sedative and hypnotics

open access: yes
Mei T. Liu, Daniel Greer, Megan Maroney
openaire   +2 more sources

Polypharmacy is associated with lower progression from MCI to Alzheimer's disease, with sex-specific patterns across drug classes. [PDF]

open access: yesAlzheimers Dement (Amst)
García-Zamora M   +5 more
europepmc   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

open access: yesVIEW, Volume 7, Issue 4, August 2026.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang   +6 more
wiley   +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, Volume 81, Issue 8, Page 2582-2632, August 2026.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
Torsten Zuberbier   +221 more
wiley   +1 more source

Clinical Trial: Lemborexant Efficacy and Safety in Liver Cirrhosis—Randomized, Double‐Blind, Crossover Clinical Trial

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 4, Page 458-470, August 2026.
RESTORE is a prospective, double‐blind, placebo‐controlled, crossover trial evaluating Lemborexant in cirrhosis at Cipto Mangunkusumo National Referral Hospital. Both 5 and 10 mg doses reduced PSQI by week 2, with sustained benefits post‐crossover. The 5 mg group improved Stroop Test performance, whereas the 10 mg group had prolonged reaction time ...
Rino Alvani Gani   +7 more
wiley   +1 more source

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