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Effect of hypoalbuminemia on drug pharmacokinetics [PDF]
Frontiers in PharmacologyHypoalbuminemia, defined as serum albumin levels below 35 g/L, is common in patients with conditions such as nephrotic syndrome, cirrhosis, or sepsis. This review examines the impact of hypoalbuminemia on the pharmacokinetics of selected drugs—such as antibiotics, immunosuppressants, antifungals, or anticonvulsants—emphasizing its role in drug efficacy
Karbownik Agnieszka
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Hypoalbuminemia, Coagulopathy, and Vascular Disease in COVID-19
Circulation Research, 2020 Hypoalbuminemia, Coagulopathy, and Vascular Disease in COVID ...
Francesco Violi +2 more
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Predictive value of hypoalbuminemia and severe hypoalbuminemia in oncologic spine surgery
Clinical Neurology and Neurosurgery, 2021Retrospective review of a prospectively collected national database.To evaluate the predictive value of hypoalbuminemia on outcomes in surgical spine oncology patients.It is well documented that patients with hypoalbuminemia (albumin 3.5 g/dl). We evaluated outcomes for metastatic oncologic spine surgery patients based on pre-operative albumin levels ...
Yaroslav, Gelfand +5 more
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Even modest hypoalbuminemia affects outcomes of colorectal surgery patients [PDF]
American Journal of Surgery, 2015 BackgroundA small decrease in the serum albumin from the normal level is a common condition in preoperative laboratory tests of colorectal surgery patients; however, there is limited data examining these patients.
Zhobin Moghadamyeghaneh +2 more
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Mechanism of hypoalbuminemia in rodents
American Journal of Physiology-Heart and Circulatory Physiology, 2005Normal albumin loss from the plasma is thought to be minimized by a number of mechanisms, including charge repulsion with the capillary wall and an intracellular rescue pathway involving the major histocompatibility complex-related Fc receptor (FcRn)-mediated mechanism.
Maria, Koltun +4 more
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Critical Care Medicine, 1998
To show how hypoalbuminemia lowers the anion gap, which can mask a significant gap acidosis; and to derive a correction factor for it.Observational study.Intensive care unit in a university-affiliated hospital.Nine normal subjects and 152 critically ill patients (265 measurements).None.Arterial blood samples analyzed for pH, PCO2, and concentrations of
J, Figge, A, Jabor, A, Kazda, V, Fencl
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To show how hypoalbuminemia lowers the anion gap, which can mask a significant gap acidosis; and to derive a correction factor for it.Observational study.Intensive care unit in a university-affiliated hospital.Nine normal subjects and 152 critically ill patients (265 measurements).None.Arterial blood samples analyzed for pH, PCO2, and concentrations of
J, Figge, A, Jabor, A, Kazda, V, Fencl
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Hypoalbuminemia in Gastric Carcinoma
Gastroenterology, 1960Summary In 9 patients suffering from gastric carcinoma, a pronounced hypoalbuminemia varying from 2 to 3 gm. per 100 ml. was found in 8. In 7 patients an abnormal fecal excretion of I 131 -polyvinylpyrrolidone was found after intravenous injection of the labeled polymer, suggesting a gastrointestinal leakage of high molecular-weight substances.
S, JARNUM, M, SCHWARTZ
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Psychosomatics, 1991
The charts of 100 delirious patients seen by a psychiatric consultation service were reviewed. The most common chronic medical problems included diabetes and cardiovascular disease, while infections and trauma were the most common acute problems.
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The charts of 100 delirious patients seen by a psychiatric consultation service were reviewed. The most common chronic medical problems included diabetes and cardiovascular disease, while infections and trauma were the most common acute problems.
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Veterinary Clinics of North America: Small Animal Practice, 2017
Hypoalbuminemia is common and associated with a variety of disease processes, including those leading to systemic inflammatory response syndrome, gastrointestinal disorders, hepatic disorders, and glomerular diseases. Some animals develop clinical signs directly caused by low serum albumin concentration. There is strong evidence that hypoalbuminemia is
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Hypoalbuminemia is common and associated with a variety of disease processes, including those leading to systemic inflammatory response syndrome, gastrointestinal disorders, hepatic disorders, and glomerular diseases. Some animals develop clinical signs directly caused by low serum albumin concentration. There is strong evidence that hypoalbuminemia is
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Hypoalbuminemia as a Cause of Pleural Effusions
Chest, 1999Alterations in Starling forces that favor pleural fluid formation include an elevation in capillary hydrostatic pressure and a fall in plasma oncotic pressure. Although venous hypertension is a well-recognized cause of pleural effusion, the frequency with which hypoalbuminemia in the absence of volume expansion leads to pleural effusion is unclear.We ...
A A, Eid, J I, Keddissi, G T, Kinasewitz
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