Antibacterial Effect of Hypochlorous Acid on Bacteria Associated with the Formation of Periodontal Biofilms: An in vitro Pilot Study [PDF]
Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2023 Objective: To evaluate the antibacterial effect of electrolytically generated hypochlorous acid on Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis.
Pablo Alejandro Millones-Gómez +11 more
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Interleukin-10 Attenuates Hypochlorous Acid-Mediated Cytotoxicity to HEI-OC1 Cochlear Cells [PDF]
Frontiers in Cellular Neuroscience, 2017 Inflammatory reaction plays a crucial role in the pathophysiology of acquired hearing loss such as ototoxicity and labyrinthitis. In our earlier work, we showed the pivotal role of otic fibrocytes in cochlear inflammation and the critical involvement of ...
Martin Mwangi +6 more
doaj +2 more sources
Hypochlorous Acid as a Potential Postsurgical Antimicrobial Agent in Periodontitis: A Randomized, Controlled, Non-Inferiority Trial [PDF]
Antibiotics, 2023 Background: Hypochlorous acid (HOCl) is an antimicrobial agent with high affinity to Gram-negative bacteria of the subgingival biofilm. It could have an equivalent or no inferiority effect to chlorhexidine (CHX) to avoid recolonization of these ...
Julio Cesar Plata +8 more
doaj +2 more sources
Highly purified hypochlorous acid water facilitates glucose metabolism and memory formation in type 2 diabetic mice associated with altered-gut microbiota [PDF]
Scientific ReportsHypochlorous acid (HOCl) is an endogenous oxidant and chlorinating agent in mammals that is effective against a broad range of microorganisms. However, the effects of exogenous HOCl on biological processes have not been reported.
Kazuki Watanabe +9 more
doaj +2 more sources
Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid. [PDF]
PLoS Pathogens, 2016 Hypochlorous acid (HOCl) is produced naturally by neutrophils and other cells to kill conventional microbes in vivo. Synthetic preparations containing HOCl can also be effective as microbial disinfectants.
Andrew G Hughson +14 more
doaj +6 more sources
Chlorination and oxidation of heparin and hyaluronan by hypochlorous acid and hypochlorite anions: effect of sulfate groups on reaction pathways and kinetics [PDF]
, 2012 Hypochlorous acid (HOCl), produced in inflammatory conditions by the enzyme myeloperoxidase, and its anion hypochlorite (OCl(-)) exist in vivo at almost equal concentrations.
Almabrok Akeel +4 more
openalex +4 more sources
Laser desorption rapid evaporative ionization mass spectrometry (LD-REIMS) demonstrates a direct impact of hypochlorous acid stress on PQS-mediated quorum sensing in Pseudomonas aeruginosa [PDF]
mSystemsTo establish infections in human hosts, Pseudomonas aeruginosa must overcome innate immune-generated oxidative stress, such as the hypochlorous acid (HOCl) produced by neutrophils.
Rob Bradley +5 more
doaj +2 more sources
International Journal of Molecular Sciences, 2022 This review discusses the formation of hypochlorous acid HOCl and the role of reactive chlorinated species (RCS), which are catalysed by the enzyme myeloperoxidase MPO, mainly located in leukocytes and which in turn contribute to cellular oxidative ...
Celia María Curieses Andrés +4 more
semanticscholar +1 more source
Research Progress of Small Molecule Fluorescent Probes for Detecting Hypochlorite
Sensors, 2021 Hypochlorous acid (HOCl) generates from the reaction between hydrogen peroxide and chloride ions via myeloperoxidase (MPO)-mediated in vivo. As very important reactive oxygen species (ROS), hypochlorous acid (HOCl)/hypochlorite (OCl−) play a crucial role
Zhi-Guo Song +3 more
doaj +1 more source
Synergistic effect of two formulations of hypochlorous acid in the treatment of 346 chronic ulcers [PDF]
, 2023 Our objective was to assess the efficacy of two successive applications of hypochlorous acid, first as a liquid and then as a gel because liquid hypochlorous acid is effective but has little residual effect, while the gel form has more residual power ...
Cerame Perez, Silvia +4 more
core +2 more sources