Results 201 to 210 of about 14,051 (235)
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Reaction of γ‐Tocopherol with Hypochlorous Acid
Lipids, 2007AbstractIn addition to being a very good antioxidant, γ‐tocopherol is also an excellent electrophile trap. This is a study of the reactivity of γ‐tocopherol with hypochlorous acid/hypochlorite, a potential biological foe that is both an oxidant and an electrophile. Aqueous sodium hypochlorite (1.72 mmol; pH 7.4) was stirred with γ‐tocopherol (0.12 mmol)
Quyen, Nguyen, Peter T, Southwell-Keely
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Chlorogenic Acid as a Natural Scavenger for Hypochlorous Acid
Biochemical and Biophysical Research Communications, 1995The effect of chlorogenic acid (CGA) on the killing of Escherichia coli by hypochlorous acid (HOCI) was examined. CGA prevented E. coli from bactericidal action of HOCI in a concentration-dependent manner. HOCI reacted rapidly with CGA. By comparison with the one- and two-electron oxidation products produced by peroxidase and phenolase reactions ...
Y, Kono +4 more
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Effects of hypochlorous acid on unsaturated phosphatidylcholines
Free Radical Biology and Medicine, 2001Effects of hypochlorous acid and of the myeloperoxidase-hydrogen peroxide-chloride system on mono- and polyunsaturated phosphatidylcholines were analyzed by means of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS).
J, Arnhold +4 more
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Kinetics and Mechanisms of Hypochlorous Acid Reactions
Archives of Biochemistry and Biophysics, 1995Hypochlorous acid (HOCl) is a strong oxidant formed in neutrophils by the myeloperoxidase-catalyzed oxidation of chloride. Using stopped-flow with spectrophotometric detection, HOCl was found to react very rapidly with glutathione and ascorbate and less rapidly with taurine.
L K, Folkes, L P, Candeias, P, Wardman
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Hypochlorous Acid Is a Potent Inhibitor of Acetylcholinesterase
Toxicology and Applied Pharmacology, 2002The role of hydrogen peroxide and peroxynitrite in the induction of airway hyperreactivity has been well described. Another reactive species which is formed during airway inflammation is hypochlorous acid (HOCl). In the present investigation the effect of HOCl on cholinergic innervation of the airway was investigated.
den Hartog, G.J.M. +4 more
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THE DECOMPOSITION OF HYPOCHLOROUS ACID
Canadian Journal of Chemistry, 1952The rate of decomposition of hypochlorous acid has been measured in aqueous solution in the presence of much sodium hypochlorite. The rate is nearly independent of the hypochlorite concentration, and proportional to the square of the hypochlorous acid concentration. Hence the mechanism proposed is[Formula: see text][Formula: see text]The first step is
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Journal of the American Chemical Society, 2013
We report the synthesis and characterization of a fluorescent probe (Hypo-SiF) designed for the detection of hypochlorous acid (HOCl) using a silicon analogue of fluorescein (SiF). The probe is regulated in an "off-on" fashion by a highly selective thioether spirocyclic nonfluorescent structure that opens to form a mixture of fluorescent products in ...
Quinn A, Best +4 more
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We report the synthesis and characterization of a fluorescent probe (Hypo-SiF) designed for the detection of hypochlorous acid (HOCl) using a silicon analogue of fluorescein (SiF). The probe is regulated in an "off-on" fashion by a highly selective thioether spirocyclic nonfluorescent structure that opens to form a mixture of fluorescent products in ...
Quinn A, Best +4 more
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THE ACTION OF HYPOCHLOROUS ACID ON ARYLIDENECYANOACETIC ACIDS
Canadian Journal of Research, 1932The action of hypochlorous acid on p-methoxybenzylidenecyanoacetic acid has been found to produce p-methoxyphenylacetic acid. When treated in the same way, o-methoxybenzylidene-, veratrylidene- and piperonylidenecyanoacetic acids give the corresponding substituted phenylacetic acids in moderately good yields.
John Alexander McRae +1 more
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Scavenging of hypochlorous acid by lipoic acid
Biochemical Pharmacology, 1991G R, Haenen, A, Bast
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