Results 31 to 40 of about 14,051 (235)

Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis

Redox Biology, 2019
Calprotectin, the major neutrophil protein, is a critical alarmin that modulates inflammation and plays a role in host immunity by strongly binding trace metals essential for bacterial growth.
Teagan S. Hoskin, Jennifer M. Crowther, Jeanette Cheung, Michael J. Epton, Peter D. Sly, Peter A. Elder, Renwick C.J. Dobson, Anthony J. Kettle, Nina Dickerhof   +8 more
doaj   +1 more source

8-Chloroadenosine induces apoptosis in human coronary artery endothelial cells through the activation of the unfolded protein response

Redox Biology, 2019
Infiltration of leukocytes within the vessel at sites of inflammation and the subsequent generation of myeloperoxidase-derived oxidants, including hypochlorous acid, are key characteristics of atherosclerosis.
Vickie Tang, Shanlin Fu, Benjamin S. Rayner, Clare L. Hawkins   +3 more
doaj   +1 more source

HOCl Responsive Lanthanide Complexes Using Hydroquinone Caging Units

Molecules, 2020
Redox biology is still looking for tools to monitor redox potential in cellular biology and, despite a large and sustained effort, reliable molecular probes have yet to emerge.
Elena Del Giorgio, Thomas Just Sørensen
doaj   +1 more source

The Use of Hypochlorous Acid Lavage to Treat Infected Cavity Wounds

Plastic and Reconstructive Surgery, Global Open, 2020
Summary:. Managing cavity wounds that cannot be cleaned using standard irrigating solution is challenging. An immunocompromised patient with a horseshoe perianal abscess was selected to represent a heavy infection in cavity wounds.
Apinut Wongkietkachorn, MD, Palakorn Surakunprapha, MD, Jakrapan Wittayapairoch, MD, Nuttapone Wongkietkachorn, MD, Supawich Wongkietkachorn, MD   +4 more
doaj   +1 more source

Antibacterial Effect of Hypochlorous Acid on Bacteria Associated with the Formation of Periodontal Biofilms: An in vitro Pilot Study

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2023
Objective: To evaluate the antibacterial effect of electrolytically generated hypochlorous acid on Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis.
Pablo Alejandro Millones-Gómez, Marcos Novoa-Herrera, Dora Jesús Maurtua-Torres, Reyma Evelyn Bacilio-Amaranto, Margarita Fe Requena-Mendizábal, Roger Calla-Poma, Tania Valentina Rosales-Cifuentes, Federico Martin Malpartida-Quispe, Carlos Alberto Minchón-Medina, Julio César Romero-Gamboa, Melissa Pinella-Vega, Roberto Carlos Ojeda-Gómez   +11 more
doaj  

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

Neural Regeneration Research
It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late stroke.
Lin-Yan Huang, Yi-De Zhang, Jie Chen, Hai-Di Fan, Wan Wang, Bin Wang, Ju-Yun Ma, Peng-Peng Li, Hai-Wei Pu, Xin-Yian Guo, Jian-Gang Shen, Su-Hua Qi   +11 more
doaj   +1 more source

Reactions of kynurenic acid with hypobromous acid and hypochlorous acid

Journal of Clinical Biochemistry and Nutrition, 2021
Kynurenic acid, a tryptophan metabolite, acts as antagonist or agonist of several receptors. Hypobromous acid (HOBr) and hypochlorous acid (HOCl) are generated by eosinophils and neutrophils. At inflammation sites, kynurenic acid may encounter HOBr and HOCl to generate products.
Suzuki, Toshinori, Morishita, Hiroyuki, Fukuhara, Kosumo   +2 more
openaire   +3 more sources

A Highly Selective Fluorescent Probe for Hypochlorous Acid in Living Cells Based on a Naphthalene Derivative

International Journal of Analytical Chemistry, 2022
Hypochlorous acid (HOCl) was crucial for maintaining the homeostasis in cells and plays vital roles in many physiological and pathological processes. In this work, a highly selective fluorescent probe for hypochlorous acid in living cells was constructed
Jingguo Sun, Junhong Xu, Qiujuan Ma, Guojiang Mao, Nannan Zhu, Meiju Tian, Linke Li, Shuzhen Liu   +7 more
doaj   +1 more source

Probing the toxic hypochlorous acid in natural waters and biosystem by a coumarin-based fluorescence probe

Ecotoxicology and Environmental Safety
Since the onset of the SARS-CoV-2 pandemic in early 2020, there has been a notable rise in sodium hypochlorite disinfectants. Sodium hypochlorite undergoes hydrolysis to generate hypochlorous acid for virus eradication.
Junyan Ma, Mingtao Zhao, Xiangtao Kong, He Li, Hua Xie, Xiaomei Yang, Zhenxing Zhang   +6 more
doaj   +1 more source

Antioxidant and cytotoxic studies for kaempferol, quercetin and isoquercitrin

Eclética Química, 2018
The aim of the present study was to investigate a cytotoxic oxidative cell stress related and the antioxidant profile of kaempferol, quercetin, and isoquercitrin. The flavonol compounds were able to act as scavengers of superoxide anion (but not hydrogen
José Carlos Rebuglio Vellosa, Luis O. Regasini, Najeh Maissar Khalil, Vanderlan da Silva Bolzani, Omar A. K. Khalil, Francine Alessandra Manente, Harli Pasquini Netto, Olga M. M. de Faria Oliveira   +7 more
doaj   +1 more source