Results 91 to 100 of about 1,069 (160)

Human Fibrinogen Concentrate and Fresh Frozen Plasma in the Management of Severe Acquired Hypofibrinogenemia in Children with Acute Lymphoblastic Leukemia: Results of a Retrospective Survey

, 2019
Objective of the Study:In this study we aimed to retrospectively evaluate how centers, belonging to the Associazione Italiana Ematologia e Oncologia Pediatrica (AIEOP), manage severe acquired hypofibrinogenemia in children with acute lymphoblastic ...
Putti M. C., Mura R. M., CORALLO, PAOLA CARMELA, Pollio B., Micalizzi C., Casale F., Giordano P., Luciani M., Colombini A., Grassi M., Testi A. M., Rizzari C., Tafuri S., Petruzziello F., Notarangelo L. D., De Leonardis F., Saracco P., Consarino C., Santoro N., Mastrodicasa E., Onofrillo D.   +20 more
core   +1 more source

The thrombotic paradox in congenital fibrinogen deficiencies: from pathophysiology to practice

Research and Practice in Thrombosis and Haemostasis
Congenital fibrinogen deficiencies (CFDs) comprise rare inherited disorders characterized by quantitative (afibrinogenemia, hypofibrinogenemia) or qualitative (dysfibrinogenemia, hypodysfibrinogenemia) abnormalities of fibrinogen.
Samin Mohsenian, Alessandro Casini, Flora Peyvandi   +2 more
doaj   +1 more source

Early Predictive Factors of Hypofibrinogenemia in Acute Trauma Patients

, 2018
Background: Uncontrolled hemorrhage still remains a major cause of trauma-associated mortality. The events resulting in acute traumatic coagulopathy, particularly hypofibrinogenemia, make control of bleeding difficult.
Shahram Paydar, Zahra Shayan, Behnam Dalfardi, Shahram Bolandparvaz, Leila Shayan, Jalal Saem   +5 more
core   +1 more source

Treatment effects of fibrinogen concentrates vs. cryoprecipitate for correcting hypofibrinogenemia in cardiac surgery patients: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine
BackgroundHypofibrinogenemia in cardiac surgery increases bleeding risk, but the efficacy and safety of fibrinogen concentrate vs. cryoprecipitate remain unclear.
Yue Chen, Wenjie Yang, Chongyang Zhao, Fujue Wang, PengWei Ren, Xuemei Liu, Tingyong Cao, Shuming Ji, Lei Chen, Deying Kang, Deying Kang   +10 more
doaj   +1 more source

Incidence and risk factors of tocilizumab-induced hypofibrinogenemia in patients with thyroid eye disease: a single-center retrospective study

Frontiers in Endocrinology
BackgroundTocilizumab, an interleukin-6 receptor antagonist, is increasingly used in moderate-to-severe thyroid eye disease. However, its association with hypofibrinogenemia remains underexplored in this population.MethodsThis single-center retrospective
Ente Wang, Qingyuan Hu, Shanshan Xu, Jianbo Zhou, Jiawei Wang, Zhihui Song, Xinglong Wang   +6 more
doaj   +1 more source

Urticaria, Fever, and Hypofibrinogenemia [PDF]

Arthritis & Rheumatology, 2014
Verena, Mohr, Ansgar, Schulz, Peter, Lohse, Christian, Schumann, Klaus-Michael, Debatin, Catharina, Schuetz   +5 more
openaire   +2 more sources

Fibrinogen gamma375 arg-->trp mutation (fibrinogen aguadilla) causes hereditary hypofibrinogenemia, hepatic endoplasmic reticulum storage disease and cirrhosis

, 2006
Hypofibrinogenemia is a rare inherited disorder characterized by low levels of circulating fibrinogen, caused by mutations within 1 of the 3 fibrinogen genes.
Spahr, Laurent, Rougemont, A. L., Neerman Arbez, Marguerite, Male, P. J., Rubbia-Brandt, Laura   +4 more
core   +1 more source

Congenital hypofibrinogenemia.

Indian pediatrics, 2004
Congenital afibrinogenemia/hypofibrinogenemia is an extremely rare coagulation disorder. We describe a case of congenital hypofibrinogenemia in a 6-year female child, who presented with recurrent ecchymotic spots with no frank bleeding.
Neeraj, Awasthy, K C, Aggarwal, H, Gupta, S, Saluja   +3 more
openaire   +1 more source

Tigecycline-associated hypofibrinogenemia: A single center, retrospective, controlled study

Background: Tigecycline-associated hypofibrinogenemia has been reported as an important adverse effect in recent years, but controlled studies minimizing confounding factors are needed.
İNKAYA, AHMET ÇAĞKAN, FIRAT, OĞUZHAN, KARA, EMRE, Demirkan, Kutay, MALKAN, ÜMİT YAVUZ   +4 more
core   +1 more source

Identification of genetic variants in the FGB gene associated with congenital hypofibrinogenemia with divergent clinical phenotype

Annals of Hematology
Congenital fibrinogen disorders are rare and clinically heterogeneous conditions that may manifest with both bleeding and thrombotic complications. The relationship between genotype and phenotype remains incompletely understood, particularly in cases ...
Kristina Maria Belakova, Rosanna Asselta, Sonia Caccia, Zuzana Kolkova, Dusan Loderer, Miroslava Drotarova, Monika Brunclikova, Sohaib Mukhtar Agouba, Veronika Voskova Gemelova, Jan Stasko, Jan Mikler, Tomas Simurda   +11 more
doaj   +1 more source