Results 21 to 30 of about 5,300 (203)

Thromboelastography as an early prediction method for hypofibrinogenemia in emergency department patients with primary postpartum hemorrhage

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Timely and accurate assessment of coagulopathy is crucial for the management of primary postpartum hemorrhage (PPH). Thromboelastography (TEG) provides a comprehensive assessment of coagulation status and is useful for guiding the treatment of
Sang-Min Kim, Chang Hwan Sohn, Hyojeong Kwon, Seung Mok Ryoo, Shin Ahn, Dong Woo Seo, Won Young Kim   +6 more
doaj   +2 more sources

Tocilizumab administration in cytokine release syndrome is associated with hypofibrinogenemia after chimeric antigen receptor T-cell therapy for hematologic malignancies [PDF]

Haematologica
Chimeric antigen receptor (CAR-) T cell therapy causes serious side effects including cytokine release syndrome (CRS). CRS-related coagulopathy is associated with hypofibrinogenemia that is thus far considered the result of disseminated intravascular ...
Markus Perl, Konstantin Herfeld, Dennis C. Harrer, Matthias Höpting, Marina Schweiger, Ulrich Sterz, Leonard Knödler, Susanne Heimerl, Leo Hansmann, Wolfgang Herr, Hendrik Poeck, Daniel Wolff, Matthias Edinger, Christina Hart, Matthias A. Fante   +14 more
doaj   +4 more sources

SEVERE HYPOFIBRINOGENEMIA IN A PATIENT WITH GIANT CELL ARTERITIS TREATED WITH TOCILIZUMAB: CASE-BASED REVIEW

Anti-Aging Eastern Europe, 2023
The Giant cell arteritis (GCA) is the most common form of systemic vasculitis in elderly patients. The treatment includes high doses of steroids and interleukin (IL)-6 inhibitor tocilizumab, especially in refractory or relapsing disease or in cases where
Željka Kardum, Ana Šimac, Kristina Frketić Marović, Ana Marija Masle, Jasminka MIlas Ahić   +4 more
doaj   +3 more sources

Pediatric Therapeutic Plasma Exchange: Characterization of Practice, Epidemiology, and Safety Profile at a Children's Hospital in the United States. [PDF]

J Clin Apher
ABSTRACT There is a need to better understand the indications and safety profiles for therapeutic plasma exchange (TPE) in children. We aimed to assess pediatric TPE practice at a large academic center by retrospective chart review from 2011 to 2022. Patient demographics and clinical information including American Society for Apheresis (ASFA) category ...
Lee BC, Adkins BD, Javanbakht A, Luu HS, Noland DK.   +4 more
europepmc   +2 more sources

HYPOFIBRINOGENEMIA (A Report of Two Cases) [PDF]

Medical Journal Armed Forces India, 1994
Hypofibrinogenemia is an uncommon bleeding disorder. Two siblings with mild bleeding diathesis were investigated and diagnosed as suffering from this disorder. The cases are discussed keeping in view of their rarity.
Harsh, Kumar, P, Sivadas, C, Lakshmanan, J R, Bhardwaj   +3 more
openaire   +4 more sources

Treatment effects of fibrinogen concentrates vs. cryoprecipitate for correcting hypofibrinogenemia in cardiac surgery patients: a systematic review and meta-analysis [PDF]

Frontiers in Cardiovascular Medicine
BackgroundHypofibrinogenemia in cardiac surgery increases bleeding risk, but the efficacy and safety of fibrinogen concentrate vs. cryoprecipitate remain unclear.
Yue Chen, Wenjie Yang, Chongyang Zhao, Fujue Wang, PengWei Ren, Xuemei Liu, Tingyong Cao, Shuming Ji, Lei Chen, Deying Kang, Deying Kang   +10 more
doaj   +2 more sources

A case of hypofibrinogenemia presenting with submental hamatoma

Bangabandhu Sheikh Mujib Medical University Journal, 2016
Hereditary hypofibrinogenemia is a rare disease and the usual presentation is difficult to stop bleeding or hamatoma in the muscle or intracranial space after injury. There may also be adverse pregnancy outcome, and increased tendency to throm­bosis. The
Mujahida Rahman, Naseeb Muhammad lrshadullah, Masuda Begum   +2 more
doaj   +3 more sources

Identification of Risk Factors and Predictive Indicators for Tigecycline‐Associated Hypofibrinogenemia

Clinical and Translational Science
To investigate the prevalence, clinical manifestations, and risk factors of hypofibrinogenemia after tigecycline use, which can disrupt coagulation and potentially hinder antimicrobial therapy.
Xiaohui Liu, Xuefeng Yuan, Long Wen, Xin Tan, Qian Sui, Jiheng Liu   +5 more
doaj   +2 more sources

A Novel Nonsense Mutation in FGB (c.1421G>A; p.Trp474Ter) in the Beta Chain of Fibrinogen Causing Hypofibrinogenemia with Bleeding Phenotype

Biomedicines, 2020
Congenital hypofibrinogenemia is a rare bleeding disorder characterized by a proportional decrease of functional and antigenic fibrinogen levels. Hypofibrinogenemia can be considered the phenotypic expression of heterozygous loss of function mutations ...
Tomas Simurda, Rui Vilar, Jana Zolkova, Eliska Ceznerova, Zuzana Kolkova, Dusan Loderer, Marguerite Neerman-Arbez, Alessandro Casini, Monika Brunclikova, Ingrid Skornova, Miroslava Dobrotova, Marian Grendar, Jan Stasko, Peter Kubisz   +13 more
doaj   +2 more sources

Tigecycline-associated hypofibrinogenemia: A case report and review of the literature

IDCases, 2018
Tigecycline, a glycylcycline-derived antibacterial that has been approved for the treatment of various infections, is widely used for multi-drug resistant bacteria.
Pei-Chun Wu, Chien-Chih Wu
exaly   +2 more sources