Results 31 to 40 of about 6,740 (215)

A C-terminal amino acid substitution in the γ-chain caused by a novel heterozygous frameshift mutation (Fibrinogen Matsumoto VII) results in hypofibrinogenaemia [PDF]

, 2010
journal ...
Fujihara Noriko, Haneishi Ayumi, Ishida Fumihiro, Ito Toshiro, Okumura Nobuo, Terasawa Fumiko, YAMAUCHI Kazuyoshi   +6 more
core   +2 more sources

Pediatric Fibrinogen PART I—Pitfalls in Fibrinogen Evaluation and Use of Fibrinogen Replacement Products in Children

Frontiers in Pediatrics, 2021
Fibrinogen is a key coagulation protein, playing a critical role in hemostasis. It is the first factor to decrease to critical levels during bleeding. Hypofibrinogenemia is an important risk factor for bleeding in clinical settings, including pediatric ...
Elise J. Huisman, Elise J. Huisman, Elise J. Huisman, Gemma Louise Crighton   +3 more
doaj   +1 more source

Case Report: Life-Threatening Post-operative Hemorrhage in Klippel–Trenaunay Syndrome Associated With Hypofibrinogenemia

Frontiers in Medicine, 2021
Klippel–Trenaunay Syndrome (KTS) is a rare congenital disorder, characterized by venous and lymphatic malformations of the skin, soft tissue, and bone, causing limb hypertrophy.
Hongna Yang, Binfeng Du, Han Liu, Yong Yao, Chen Li   +4 more
doaj   +1 more source

Neutralization of IFN-γ reverts clinical and laboratory features in a mouse model of macrophage activation syndrome. [PDF]

, 2018
BACKGROUND: The pathogenesis of macrophage activation syndrome (MAS) is not clearly understood: a large body of evidence supports the involvement of mechanisms similar to those implicated in the setting of primary hemophagocytic lymphohistiocytosis ...
Bracaglia, Claudia, Caiello, Ivan, Chatel, Laurence, De Min, Cristina, Fabrizio De Benedetti, And, Ferlin, Walter G., Grom, Alexei A., Marasco, Emiliano, Pascarella, Antonia, Prencipe, Giusi, Strippoli, Raffaele   +10 more
core   +1 more source

Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern. The fragile balance between infections and autoimmunity [PDF]

, 2020
On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
Diamanti, A. P., Lagana, B., Pioli, C., Rosado, M. M., Sesti, G.   +4 more
core   +2 more sources

A ruptured vulvar labial artery pseudoaneurysm causes a secondary postpartum hemorrhage: A case report. [PDF]

, 2020
Background:Postpartum hemorrhage is the most common cause of maternal morbidity in the United States. However, secondary postpartum hemorrhage is rare and includes pseudoaneurysms, which represent only 3.3% of all cases of secondary postpartum hemorrhage.
Lane, Felicia, Leaf, Marie-Claire, Schmidt, Luke, Serna-Gallegos, Tasha   +3 more
core  

A mutation in caspase-9 decreases the expression of BAFFR and ICOS in patients with immunodeficiency and lymphoproliferation [PDF]

, 2015
Lymphocyte apoptosis is mainly induced by either death receptor-dependent activation of caspase-8 or mitochondria-dependent activation of caspase-9. Mutations in caspase-8 lead to autoimmunity/lymphoproliferation and immunodeficiency. This work describes
Boggio, E, Cappellano, G, Chiocchetti, A., Clemente, N, Dianzani, C, Dianzani, I, Dianzani, U, Gigliotti, Cl, Notarangelo, Ld, Orilieri, E, Pignata, C, Quinti, Isabella, Ramenghi, U, Santoro, C, Toth, E, Valletti, Pa   +15 more
core   +2 more sources

Hepatic fibrinogen storage disease due to the fibrinogen γ375 Arg → Trp mutation "fibrinogen aguadilla" is present in Arabs

The Saudi Journal of Gastroenterology, 2014
The mutation γ375Arg → Trp (fibrinogen Aguadilla) is one of four mutations (Brescia, Aguadilla, Angers, and AI duPont) capable of causing hepatic storage of fibrinogen.
Abdulrahman Al-Hussaini, Abdulhadi Altalhi, Imad El Hag, Hussa AlHussaini, Paola Francalanci, Isabella Giovannoni, Francesco Callea   +6 more
doaj   +1 more source

Angiosarcoma of the breast with hypofibrinogenemia: A rare case report and review of the literature

Frontiers in Oncology, 2022
BackgroundBreast angiosarcoma is a rare malignant tumor, accounting for approximately 0.04% of all breast malignancies. Angiosarcoma of the breast with hypofibrinogenemia is even rarer and has not been described in man.
Ran An, Jing-Yi Ma, Xi-Hao Ni, Chang-Liang Wang   +3 more
doaj   +1 more source

Peste des Petits Ruminants: Aetiology, Pathology, Immunology, Disease Status in Africa, Diagnosis, Control, Prevention and Treatment: A Review

Notulae Scientia Biologicae, 2019
Peste des petits ruminants (PPR) is a disease of economic and veterinary importance leading to considerable economic losses. PPR affects small domestic and wild ruminants.
Iniobong C. I. UGOCHUKWU, Chukwunonso K. EZEASOR, Onyinyechukwu A. AGINA, Davinson C. ANYOGU, Ijeoma C. CHUKWUDI, Sunday I. IDOKO, Emmanuel I. UGOCHUKWU   +6 more
doaj   +1 more source