Results 31 to 40 of about 5,300 (203)
Severe haemorrhagic diathesis due to acquired hypofibrinogenemia in a patient with early T-cell precursor acute lymphoblastic leukaemia/lymphoma: a case report [PDF]
Frontiers in Cardiovascular Medicine, 2023 The most frequent haematological malignancy associated with acquired hypo/dysfibrinogenemia is multiple myeloma. We present an unusual case of severe haemorrhagic diathesis due to acquired hypofibrinogenemia in a patient with early T-cell precursor acute
Luca Spiezia +4 more
doaj +2 more sources
Hypofibrinogenemia due to Novel 316 Asp → Tyr Substitution in the Fibrinogen Bβ Chain
Thrombosis and Haemostasis, 2001 SummaryWe investigated the molecular basis of hypofibrinogenemia in a woman with a plasma fibrinogen of 1.0 mg/mL. After sequencing the coding region and intronic boundaries of all three fibrinogen genes a single heterozygous GACTAC mutation was ...
Peter M George, Stephen O Brennan
exaly +2 more sources
Thrombosis Journal, 2021 Background In patients with infectious diseases, disseminated intravascular coagulation (DIC) is often diagnosed without the fibrinogen value. The relationship between hypofibrinogenemia and outcomes of DIC in infectious diseases has thus remained ...
Kazuo Kawasugi +11 more
doaj +1 more source
Frontiers in Pediatrics, 2020 Background: Neonatal hypofibrinogenemia is often asymptomatic but can manifest as hemorrhage.Objective: This study was conducted to characterize clinical characteristics of neonates with hypofibrinogenemia and identify factors associated with hemorrhage ...
Weijun Zhou +5 more
doaj +1 more source
Addressing some challenges of congenital fibrinogen disorders in 2023 and beyond
Bleeding, Thrombosis and Vascular Biology, 2023 Congenital fibrinogen disorders (CFD) include several types and subtypes of fibrinogen deficiency, resulting from monoallelic or biallelic mutations in one of the three fibrinogen genes. While it is relatively easy to make an accurate diagnosis based on
Cristina Santoro, Alessandro Casini
doaj +3 more sources
Preeclampsia complicated with hypofibrinogenemia: 2 case reports and review of the literature
BMC Pregnancy and Childbirth, 2023 Background Preeclampsia complicated with hypofibrinogenemia is a rare disorder. We report two cases of severe preeclampsia complicated with hypofibrinogenemia followed by postpartum haemorrhage (PPH).
Shiguang Li +3 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Background: Tigecycline was recently found to cause coagulation disorders, especially hypofibrinogenemia, which may interfere with the administration of antimicrobial therapy.
Bing Leng +15 more
doaj +1 more source
Pediatric Fibrinogen PART II—Overview of Indications for Fibrinogen Use in Critically Ill Children
Frontiers in Pediatrics, 2021 Bleeding is frequently seen in critically ill children and is associated with increased morbidity and mortality. Fibrinogen is an essential coagulation factor for hemostasis and hypofibrinogenemia is an important risk factor for bleeding in pediatric and
Gemma Louise Crighton +3 more
doaj +1 more source
Frontiers in Oncology, 2020 While cancer is often related to hyperfibrinogenemia, it is rarely related to hypofibrinogenemia. Specifically, gastric cancer concomitant with unprovoked hypofibrinogenemia and the corresponding treatment approach have been rarely reported. We presented
Shuzhen Ma +10 more
doaj +1 more source
, 2020 Fibrinogen is essential for normal hemostasis. Congenital fibrinogen disorders (afibrinogenemia, hypofibrinogenemia, dysfibrinogenemia and hypodysfibrinogenemia), caused by pathogenic variants in the genes FGA, FGB and FGG, have the potential of causing ...
Rossing, Maria +9 more
core +2 more sources