Results 31 to 40 of about 4,202 (211)

A Case of Severe COVID-19 in a Patient with Good's Syndrome

European Journal of Case Reports in Internal Medicine, 2021
Good’s syndrome is a rare adult-onset combined immunodeficiency. The association of hypogammaglobulinaemia with a history of recurrent infectious or autoimmune manifestations in a middle-aged patient with evidence of a mediastinal mass should lead to the
Maria Duarte, Luciana Faria, Catarina Patronillo, Sónia da Costa Fernandes, Vera Seara   +4 more
doaj   +1 more source

Susceptibility to infections and adaptive immunity in adults with heart failure

ESC Heart Failure, 2022
Aims Heart failure (HF) is a systemic inflammatory disorder with infections being an important cause of morbidity and mortality. We asked if HF patients have a higher susceptibility to infections compared with the general population and if a subtle ...
Ulrich Salzer, Alisa Müller, Qian Zhou, Alexandra Nieters, Sebastian Grundmann, Claudia Wehr   +5 more
doaj   +1 more source

Seasonal relapsing minimal change disease: a novel strategy for avoiding long-term immunosuppression. [PDF]

, 2012
BACKGROUND: We describe the case of a young woman with seasonal allergic rhinitis who presented with signs of a lower respiratory tract infection, acute renal impairment and the nephrotic syndrome, demonstrated on biopsy to be due to minimal change ...
Cook, HT, Lawrence, C, Lightstone, L
core   +2 more sources

B Cell Therapies, Approved and Emerging: a Review of Infectious Risk and Prevention During Use [PDF]

, 2015
The development of B cell-targeted biologics represents a major advance in the treatment of autoimmune rheumatic diseases. As with other immunosuppressive agents, risk of infection is a key clinical concern.
Buch, MH, Md Yusof, MY, Vital, EM
core   +1 more source

Humoral and functional SARS-CoV-2-specific T-cell responses elicited in chronic lymphocytic leukaemia patients with GEO-CM04S1 a synthetic MVA-vectored COVID-19 vaccine. [PDF]

Br J Haematol
British Journal of Haematology, Volume 208, Issue 2, Page 711-715, February 2026.
Ortega-Francisco S, Prudente de Aquino MT, La Rosa C, Chiuppesi F, Gutierrez MA, Miller J, Li J, Mack-Onyeike J, Zhou Y, Zhou Q, Kaltcheva T, Patterson A, Dempsey S, Thomas S, Tiemann K, Yang D, Rida W, Wussow F, McKee K, Taplitz R, Raiden E, Siddiqi T, Rosen S, Diamond DJ, Danilov A.   +24 more
europepmc   +2 more sources

Secondary antibody deficiency: a complication of anti-CD20 therapy for neuroinflammation [PDF]

, 2018
B-cell depleting anti-CD20 monoclonal antibody therapies are being increasingly used as long-term maintenance therapy for neuroinflammatory disease compared to many non-neurological diseases where they are used as remission-inducing agents.
Constantinescu, C., Jacob, A., Jolles, Stephen, Paling, D., Robertson, Neil, Tallantyre, Emma, Whittam, D. H.   +6 more
core   +2 more sources

Rituximab Unveils Hypogammaglobulinemia and Immunodeficiency in Children with Autoimmune Cytopenia [PDF]

, 2020
BACKGROUND: Rituximab (RTX; anti-CD20 mAb) is a treatment option in children with refractory immune thrombocytopenia, autoimmune hemolytic anemia (AHA), and Evans syndrome (ES). Prevalence and clinical course of RTX-induced hypogammaglobulinemia in these
Angarano, R., Barzaghi, F., Bava, Anna, Bertolini, P., Biondi, A., Cancrini, C., Chini, L., Corti, P., D'Alba, I., Gabelli, M., Gallo, V., Giancotta, C., Giordano, P., Graziani, S., Lassandro, G., Marinoni, M., Martire, B., Mastrodicasa, E., Miano, M., Moschese, V., Naviglio, S., Ottaviano, Gianmarco, Pignata, C., Saracco, P., Sibson, K., Trizzino, A., Verzegnassi, F.   +26 more
core   +1 more source

Colorectal cancer in patients with X-linked agammaglobulinaemia [PDF]

, 1993
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Meer, J.W.M. van der, Munster, I.P. van, Nagengast, F.M., Schellekens, P.T.A., Weening, R.S.   +4 more
core   +5 more sources

Prolonged Impairment of Immunological Memory After Anti-CD20 Treatment in Pediatric Idiopathic Nephrotic Syndrome

Frontiers in Immunology, 2019
Anti-CD20 therapy is effective in idiopathic nephrotic syndrome (INS). However, transient or sustained hypogammaglobulinemia predisposing to an increased risk of infectious diseases can follow treatment in some patients. We analyzed the long-term effects
Manuela Colucci, Rita Carsetti, Jessica Serafinelli, Salvatore Rocca, Laura Massella, Antonio Gargiulo, Anna Lo Russo, Claudia Capponi, Nicola Cotugno, Ottavia Porzio, Andrea Onetti Muda, Paolo Palma, Francesco Emma, Francesco Emma, Marina Vivarelli, Marina Vivarelli   +15 more
doaj   +1 more source

Real-life drug retention rate and safety of rituximab when treating rheumatic diseases: a single-centre Swiss retrospective cohort study

Arthritis Research & Therapy, 2023
Background In Switzerland, rituximab (RTX) is licenced for the treatment of rheumatoid arthritis (RA) and ANCA-associated vasculitis (AAV) but is frequently used off-label to treat other auto-immune diseases (AID), especially connective tissue diseases ...
Alexandre Dumusc, Fahad Alromaih, Matthieu Perreau, Thomas Hügle, Pascal Zufferey, Diana Dan   +5 more
doaj   +1 more source