Results 11 to 20 of about 4,202 (211)

Hepatic Vascular Involvement in Adenosine Deaminase 2 Deficiency (DADA2): Case Reports and Literature Review [PDF]

Diagnostics
Background and Clinical Significance: Deficiency of Adenosine Deaminase 2 (DADA2) is a rare monogenic vasculopathy characterised by systemic inflammatory and immunodeficiency features.
Mihaela Sparchez, Laura Damian, Mihai Adrian Socaciu, Otilia Fufezan, Zeno Sparchez   +4 more
doaj   +2 more sources

Nodular lymphoid hyperplasia with hypogammaglobulinaemia [PDF]

Gut, 1972
A patient with nodular lymphoid hyperplasia, who manifested defects in cellular immunity, is presented. The clinical course is discussed and a review included of the 23 patients thus far reported with nodular lymphoid hyperplasia and hypogammaglobulinaemia.
A B, Ajdukiewicz, G R, Youngs, I A, Bouchier   +2 more
exaly   +3 more sources

Obinutuzumab versus Rituximab to maintain remission in children with steroid-dependent and frequently relapsing nephrotic syndrome: the OBIRINS study protocol, a double-blind randomised controlled trial [PDF]

BMJ Open
Introduction There is an unmet clinical need for the development of novel treatment strategies to improve the outcome of children with frequent relapsing or steroid-dependent nephrotic syndrome.
Florentia Kaguelidou, Julien Hogan, Anne-Laure Sellier-Leclerc, Isabelle Vrillon, Olivia Boyer, Sophie Guilmin-Crepon, Claire Dossier, Thomas Simon, Marc Fila, Cyrielle Parmentier, Charlotte Samaille, Gwenaelle Roussey-Kesler, Marie Magnavacca, Yannis Chartier, Ferielle Louillet, Ariane Zaloszyc, Djamel Elaribi, Sabrina Bouatia   +17 more
doaj   +2 more sources

Gamma gap and albumin-globulin ratio show poor sensitivity for monoclonal gammopathy screening in South Africa [PDF]

African Journal of Laboratory Medicine
Background: Monoclonal gammopathies, including multiple myeloma, present significant challenges in sub-Saharan Africa. Diagnosis is often missed because of limited screening tools.
Njabulo Khumalo, Cameron A. Francis, Siphiwe M. Baloyi, Jody A. Rusch   +3 more
doaj   +2 more sources

Demographic, clinical, and immunological features in combined immunodeficiency patients: a comparative analysis of those with and without pulmonary manifestations – a multicenter study from Iran [PDF]

BMC Pulmonary Medicine
Background Combined immunodeficiency (CID) involves profound defects in B and T lymphocyte development and function. This study examined clinical and immunological phenotypes of CID patients with and without pulmonary manifestations.
Ghamartaj Khanbabaee, Matin Pourghasem, Mahnaz Jamee, Seyed Ahmad Tabatabaii, Mitra Khalili, Samin Sharafian, Mehrnaz Mesdaghi, Mahnaz Sadeghi-Shabestari, Armin Shirvani, Saeid Sadr, Arefeh Zahmatkesh, Samaneh Delavari, Narges Eslami, Nazanin Farahbakhsh, Mahboubeh Mansouri, Ebrahim Tabiei, Seyedeh Zalfa Modarresi, Abdolhamid Taghizadeh Behbahani, Golnaz Eslamian, Mazdak Fallahi, Javad Enayat, Shahrzad Fallah, Mahsa Pourghasem, Asghar Aghamohammadi, Zahra Chavoshzadeh   +24 more
doaj   +2 more sources

Long-term safety and efficacy of the combination of belimumab and rituximab in the treatment of severe and refractory SLE: a preliminary report [PDF]

Lupus Science and Medicine
Objective Combination therapy with rituximab and belimumab is a novel treatment strategy for severe SLE and lupus nephritis. Phase II studies have shown promising results, although long-term data are currently lacking.
Tineke Kraaij, Cees van Kooten, Y K Onno Teng, Tom Huizinga, Eline J Arends, Robbert J Goekoop, Ton Rabelink, Mieke van Schaik, Marjolein J A L Wetzels, Stéphanie H Verbruggen, Sandra W van der Kooij, Sylvia W A Kamerling   +11 more
doaj   +2 more sources

Hypogammaglobulinaemia [PDF]

The Journal of Laryngology & Otology, 1963
This article reviews the primary immunodeficiencies that result in hypogammaglobulinemia or predominantly antibody deficiency disorders. This group makes up the largest proportion of patients with primary immunodeficiency. Significant advances have been made in understanding the molecular basis and clinical characteristics of patients with the more ...
Patrick F K, Yong, Ronnie, Chee, Bodo, Grimbacher   +2 more
  +6 more sources

Serum immunoglobulin G as a discriminator of infection in follicular lymphoma patients undergoing chemotherapy with bendamustine in combination with rituximab

Hematology, 2022
Objectives: Chemotherapy, including bendamustine, usually causes lymphocytopaenia and hypogammaglobulinaemia as side effects in patients with haematological malignancies.
Akie Hirata, Kaname Miyashita, Takafumi Tanaka, Kiyoko Hirata, Taisuke Narazaki, Hayato Utsunomiya, Hirofumi Ohno, Eriko Nakashima, Yoshimichi Tachikawa, Ilseung Choi, Kenichi Taguchi, Youko Suehiro   +11 more
doaj   +1 more source

Chronic Giardiasis in a Case of Common Variable Immunodeficiency (CVID): A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Common Variable Immunodeficiency (CVID) is a primary immunodeficiency characterized by low antibody levels and recurrent infections. This makes an individual more prone to recurrent respiratory and gastrointestinal tract infections. In cases where there
Supriya M. Paranjpe, Avani Koticha, Preeti R Mehta   +2 more
doaj   +1 more source

Good's syndrome presenting with CMV pneumonitis and oesophageal candidiasis: A case report

Respirology Case Reports, 2022
Good's syndrome is an acquired combined T‐ and B‐cell immunodeficiencies and patients are prone to opportunistic infections. The diagnosis is based on a characteristic immunoglobulin and lymphocyte subset profile, with clinical features of thymoma ...
Chin Tong Kwok, Yiu Cheong Yeung
doaj   +1 more source