Results 21 to 30 of about 4,202 (211)

Immunoglobulinopathies in patients with angioimmunoblastic T-cell lymphoma [PDF]

Терапевтический архив, 2018
Contex. Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of non-Hodgkins lymphoma, characterized by generalized lymphadenopathy, hepatosplenomegaly and dysproteinemia. Hypergammaglobulinaemia is revealed in 50-83% pts with AITL.
N G CHERNOVA, N P SOBOLEVA, S A MARIINA, Y V SIDOROVA, M N SINITSYNA, V N DVIRNYK, D S BADMAZHAPOVA, Y E VINOGRADOVA, E E ZVONKOV, V G SAVCHENKO   +9 more
doaj   +1 more source

A Retrospective Analysis of Rituximab Treatment for B Cell Depletion in Different Pediatric Indications

Frontiers in Pediatrics, 2021
Background: Rituximab (RTX) is used in cancer therapy as well as in the treatment of autoimmune diseases and alloimmune responses after transplantation. It depletes the disease-causing B cells by binding to the CD (cluster of differentiation) 20 antigen.
Merlin Wennmann, Simone Kathemann, Kristina Kampmann, Sinja Ohlsson, Anja Büscher, Dirk Holzinger, Adela Della Marina, Elke Lainka   +7 more
doaj   +1 more source

Human Cytomegalovirus Infection in Haematopoietic Stem Cell Transplant Recipients and CAR T Cell Recipients - PART 1: Risk Factors, Clinical Impact and Immune Response. [PDF]

Rev Med Virol
ABSTRACT Human cytomegalovirus (HCMV) is one of the most important opportunistic pathogens in immunocompromised individuals, including allogeneic haematopoietic stem cell transplant (allo‐HSCT) recipients. In allo‐HSCT, HCMV seropositivity of the recipient and donor is associated with inferior survival outcomes, and post‐transplant HCMV reactivation is
Kaplan D, Blyth E, Sutrave G, Yong MK, Gottlieb DJ, Abendroth A, Slobedman B, Stern L.   +7 more
europepmc   +2 more sources

Recurrent COVID‐19 infection in a case of rituximab‐induced hypogammaglobulinaemia

Respirology Case Reports, 2022
Patients with immunodeficiency are at an increased risk of recurrent COVID‐19 infection. They may lack the natural immune response that usually confers long‐lasting immunity.
Jefferson Daniel, Balamugesh Thangakunam, Barney Thomas Jesudason Isaac, Mahesh Moorthy, Devasahayam Jesudas Christopher   +4 more
doaj   +1 more source

Targeted next-generation sequencing revealed a novel homozygous mutation in the LRBA gene causes severe haemolysis associated with Inborn Errors of Immunity in an Indian family.

Hematology, 2022
Objectives LPS-responsive beige-like anchor protein (LRBA) deficiency abolishes LRBA protein expression due to biallelic mutations in the LRBA gene that lead to autoimmune manifestations, inflammatory bowel disease, hypogammaglobulinemia in early stages,
Prabhakar Kedar, Rashmi Dongerdiye, Shanmukhaiah Chandrakala, Umair Ahmed Bargir, Manisha Madkaikar   +4 more
doaj   +1 more source

Hypogammaglobulinaemia with Whipple's disease [PDF]

Postgraduate Medical Journal, 1973
Summary The patient, a 54-year-old housewife, was well until the age of 40 years when she developed repeated infections. During the next 10 years recurrent attacks of diarrhoea also appeared and were associated with weight loss, increased skin pigmentation, and later the occurrence of arthralgia and polyserositis.
M, Cochran, M G, Cook, J C, Gallagher, M, Peacock   +3 more
openaire   +2 more sources

Iatrogenic antibody deficiency from B-cell targeted therapies in autoimmune rheumatic diseases

Lupus Science and Medicine, 2019
B-cell targeted therapies (BCTT) are now widely used in autoimmune rheumatic diseases, including SLE, antineutrophil cytoplasmic antibody-associated vasculitis and rheumatoid arthritis.
Chetan Mukhtyar, Sonali Wijetilleka, Mohammed Yousuf Karim   +2 more
doaj   +1 more source

Case report of Ureaplasma urealyticum meningitis in a patient with thymoma and hypogammaglobulinaemia

BMC Infectious Diseases, 2021
Background Ureaplasma urealyticum (UU) is found among the normal vaginal flora in a considerable proportion of asymptomatic women; however, adult central nervous system (CNS) infection of UU is extremely rare.
Ting Zhang, Haiyan Li, Shuping Hou, Huanxin Yu, Wei Yue   +4 more
doaj   +1 more source

Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]

, 2014
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
AA Bousfiha, B Gathmann, B Gathmann, B Piqueras, B Seymour, C Casulo, C Wehr, DF Florescu, E Becerra, E Castigli, ES Resnick, FA Bonilla, G Gunther, H Chapel, H Chapel, H Griffiths, Hilary J. Longhurst, HM Chapel, I De La Torre, I Quinti, J Blore, J Shortt, JA Freeman, JD Edgar, John Dempster, JS Orange, JS Orange, K Warnatz, K Warnatz, L Mouthon, Lorena Lorenzo, M Lucas, M Makatsori, M Yomota, Matthaios Speletas, Matthew Buckland, ME Conley, ME Rose, MJ Boumans, N Ozaras, N Venhoff, NH Yip, P Bright, P McLaughlin, P Wood, R Herriot, S Baris, S Bernatsky, S Molica, Sai S. Duraisingham, Sofia Grigoriadou, SS Duraisingham, T Kawano, U Salzer, W Al-Herz, W Strober   +55 more
core   +3 more sources

Encephalomyelitis in primary hypogammaglobulinaemia [PDF]

Brain, 1996
The neurological features of 13 patients with primary hypogammaglobulinaemia are described. Seven patients had X-linked agammaglobulinaemia (XLA) and six had common variable immunodeficiency (CVID). Three clinical pictures emerged: (i) a progressive myelopathy (one case); (ii) a myelopathy progressing to an encephalopathy (four cases); (iii) a pure ...
P, Rudge, A D, Webster, T, Revesz, T, Warner, T, Espanol, C, Cunningham-Rundles, N, Hyman   +6 more
openaire   +2 more sources