Rituximab and hypogammaglobulinemia [PDF]
El rituximab (RTX), un anticuerpo quimérico anti-CD20 que induce la depleción de linfocitos B, es utilizado para el tratamiento de enfermedades linfoproliferativas y autoinmunes.
Fernández Romero, Diego S. +5 more
core
TACI mutations and impaired B-cell function in subjects with CVID and healthy heterozygotes [PDF]
Mutations in the gene coding for the transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) are found in 8% to 10% of subjects with common variable immunodeficiency (CVID).
Bonhomme +33 more
core +2 more sources
Objective: Vancomycin-resistant enterococci (VRE) are common pathogens of hospital-acquired infection. Long hospitalization periods, use of broadspectrum antibiotics, and immunosuppression are major risks for VRE colonization.
Elif Gülsüm Ümit +2 more
doaj +1 more source
Cytomegalovirus infection does not impact on survival or time to first treatment in patients with chronic lymphocytic leukemia [PDF]
Human cytomegalovirus (HCMV) is a widely prevalent herpes virus which establishes a state of chronic infection. The establishment of CMV‐specific immunity controls viral reactivation and leads to the accumulation of very large numbers of virus‐specific T
Adami +38 more
core +4 more sources
Noninvasive Urinary Monitoring of Progression in IgA Nephropathy. [PDF]
Standard methods for detecting and monitoring of IgA nephropathy (IgAN) have conventionally required kidney biopsies or suffer from poor sensitivity and specificity.
Fervenza, Fernando C +4 more
core +1 more source
When Autoimmunity Meets Malignancy: A Rare Case of Concomitant Systemic Lupus and Multiple Myeloma
The association between systemic lupus erythematosus (SLE) and multiple myeloma (MM) is rare, with fewer than 20 cases reported in the literature, raising questions about the link between chronic immune dysregulation and oncogenesis.
Solohery Jean Noël Ratsimbazafy +7 more
doaj +1 more source
The lung in primary immunodeficiencies: new concepts in infection and inflammation [PDF]
Immunoglobulin replacement therapy (IGRT) has contributed critically to the management of primary antibody deficiencies (PAD) and the decrease in pneumonia rate.
Baumann, Ulrich +4 more
core +4 more sources
A Late-Diagnosed Case of Common Variable Immunodeficiency
Common Variable Immunodeficiency (CVID) is the most common form of primary immunodeficiency (PID). CVID is characterized by decreased serum immunoglobulin levels, decreased or absent antibody production, and normal or low B-lymphocyte counts.
Coşkun Doğan +2 more
doaj +1 more source
Multisystem disorder associated with a pathogenic variant in CLCN7 in the absence of osteopetrosis
Background We clinically and genetically evaluated a Taiwanese boy presenting with developmental delay, organomegaly, hypogammaglobulinemia and hypopigmentation without osteopetrosis.
Chung‐Lin Lee +8 more
doaj +1 more source
Effect of monomeric immunoglobulin G (IgG) on the clearance of soluble aggregates of IgG in man [PDF]
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Breedveld, F.C. +8 more
core +1 more source

