Results 81 to 90 of about 13,781 (198)
A Late-Diagnosed Case of Common Variable Immunodeficiency
Common Variable Immunodeficiency (CVID) is the most common form of primary immunodeficiency (PID). CVID is characterized by decreased serum immunoglobulin levels, decreased or absent antibody production, and normal or low B-lymphocyte counts.
Coşkun Doğan +2 more
doaj +1 more source
Integrated Engineering of CAR‐T Cells for Solid Tumours
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang +5 more
wiley +1 more source
BAFF and APRIL Receptors in B Cell Immunity and Autoimmunity
ABSTRACT BAFF and APRIL are TNF superfamily proteins that bind to BAFFR, TACI and BCMA, members of the TNF receptor superfamily. These proteins have both unique and overlapping roles in B cell development and survival and are major therapeutic targets for antibody‐ and B‐cell‐driven pathologies.
Daisy H. Luff +2 more
wiley +1 more source
Multiple Sclerosis anti-CD20 (Ocrelizumab) therapy inducing hypogammaglobulinemia
Nora Abdul-Aziz +3 more
doaj +1 more source
Tubulointerstitial Nephritis With Uveitis (TINU) Syndrome: A Case Series and Review of Literature
ABSTRACT Tubulointerstitial nephritis with uveitis (TINU) syndrome is a rare disorder characterised by the simultaneous or sequential occurrence of acute tubulointerstitial nephritis and uveitis, in the absence of systemic disease. Its true prevalence is likely underestimated, as renal and ocular manifestations may not appear concurrently. We conducted
Weaam Ali +5 more
wiley +1 more source
Multisystem disorder associated with a pathogenic variant in CLCN7 in the absence of osteopetrosis
Background We clinically and genetically evaluated a Taiwanese boy presenting with developmental delay, organomegaly, hypogammaglobulinemia and hypopigmentation without osteopetrosis.
Chung‐Lin Lee +8 more
doaj +1 more source
ABSTRACT The 2019 International Pediatric Transplant Association (IPTA) consensus conference assessed available evidence and developed recommendations for various aspects of care relating to post‐transplant lymphoproliferative disorders (PTLD) after solid organ transplantation in children.
Michael Green +7 more
wiley +1 more source
Citation: 'hypogammaglobulinemia' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13246 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire +1 more source
A Review of Primary Immune Deficiency Disorders
This scenario-based review of primary immunodeficiency diseases (PIDD) discusses the differential diagnosis, usual presentations, work-up, and treatment of children with the most commonly encountered immune disorders.
Talin Darian +4 more
doaj
Rethinking secondary immunodeficiency: a cross-domain pathway framework for risk stratification
BackgroundSecondary immunodeficiency (SID) arises from malignancy, immunomodulatory therapies, organ dysfunction, chronic infection, malnutrition, and aging.
Iqra Mumtaz
doaj +1 more source

